Rhythm Pharmaceuticals(RYTM)

BOSTON, MA

Pharmaceutical1 H-1B visas (FY2023)

Website LinkedIn Careers Page

Focus: Peptide Therapeutics

Rhythm Pharmaceuticals is a life sciences company focused on Peptide Therapeutics.

Neurology

Funding Stage

PUBLIC

Employees

201-500

Open Jobs

Products & Portfolio (1)

IMCIVREE

setmelanotide

Peak

PeptideSUBCUTANEOUS · SOLUTION

Melanocortin 4 Receptor Agonists

2020

Pipeline & Clinical Trials

Single Chamber Implantable Cardioverter Defibrillator

Ventricular Tachycardia

N/A

Clinical Trials (1)

NCT00157820DATAS: The Dual Chamber & Atrial Tachyarrhythmias Adverse Events Study

N/A

Silverlon®

Infections

N/A

Chronicle Implantable Hemodynamic Monitor

Heart Failure

N/A

Clinical Trials (1)

NCT00991120Extension Phase of the Chronicle® Offers Management to Patients With Advanced Signs & Symptoms of Heart Failure Study

N/A

Observational

Bradycardia Sinus

N/A

Clinical Trials (1)

NCT06910059The CT-verified Data Collection Study to Investigate the Correlation Between the Leadless Pacemaker Tip Location and Echo, ECG

N/A

Endeavor Resolute Zotarolimus-Eluting Coronary Stent System

Coronary Artery Disease

N/A

Clinical Trials (1)

NCT00752128RESOLUTE International Registry: Evaluation of the Resolute Zotarolimus-Eluting Stent System in a 'Real-World' Patient Population

N/A

Evera MRI ICD System

Arrhythmias, Cardiac

N/A

Clinical Trials (1)

NCT03261063China Evera MRI® Study

N/A

InSync Model 8040

Heart Failure

N/A

Clinical Trials (1)

NCT00273182InSync Model 8040 (InSync) and InSync III Model 8042 (InSync III) Registry

N/A

Personalized cardiac pacing

Heart Failure With Preserved Ejection Fraction (HFpEF)

N/A

Clinical Trials (1)

NCT06678841ELEVATE-HFpEF Clinical Study

N/A

Attain Success Lead

Heart Failure

N/A

Clinical Trials (1)

NCT00990964Attain Success Clinical Trial

N/A

Endeavor Resolute Stent

Coronary Artery Disease

N/A

Clinical Trials (1)

NCT00850213Assessment of Clinical Performance and Costs of the Endeavor Resolute Stent "in Real Life" in Spain.

N/A

CRT

Heart Failure

N/A

Clinical Trials (1)

NCT00822146Cardiac Resynchronization Therapy (CRT) Efficacy Study

N/A

Cardiac Resynchronization Therapy+Implantable Cardioverter Defibrillator

Congestive Heart Failure, Atrial Arrhythmia, Atrial Tachyarrhythmia, Atrial Fibrillation

N/A

Clinical Trials (1)

NCT00268320Clinical Investigation of the Medtronic Concerto™ Device

N/A

Pacemaker lower rate setting

Sinus Node Dysfunction

N/A

Clinical Trials (1)

NCT05766462Allometric-Pace Study

N/A

Investigational LINQ™ HF RAMware

Heart Failure

N/A

Clinical Trials (1)

NCT03608826Relationship Between LINQ™ Subcutaneous Impedance and Right-sided Hemodynamic Measurements

N/A

Assessment of AAIR Pacing Treatment for Heart Failure Patients With Chronotropic Incompetence

Heart Failure

N/A

Clinical Trials (1)

NCT03071952Assessment of AAIR Pacing Treatment for Heart Failure Patients With Chronotropic Incompetence

N/A

prayer

Coronavirus Infection

N/A

Protecta VR-ICD

Tachyarrhythmias

N/A

Clinical Trials (1)

NCT00982397Safety and Clinical Performance of the Protecta ICD and CRT-D

N/A

Reveal® DX or Reveal® XT Insertable Cardiac Monitor

Arrhythmias, Cardiac

N/A

Clinical Trials (1)

NCT01168427Reveal In-Office Implants

N/A

Magnetic Resonance Imaging

Atrial Fibrillation

N/A

Clinical Trials (1)

NCT01520532Evaluation of the Incidence of Cerebral Lesions Post Pulmonary Vein Ablation Catheter (PVAC)

N/A

ICD or CRT-D Device

Sudden Cardiac Arrest

N/A

Clinical Trials (1)

NCT02099721Improve Sudden Cardiac Arrest Study

N/A

Intervention Pacing Features

Atrial Fibrillation

N/A

Clinical Trials (1)

NCT00289289Reducing Episodes by Septal Pacing Efficacy Confirmation Trial (RESPECT)

N/A

Pacing Lead

Heart Failure

N/A

Clinical Trials (1)

NCT00269230Attain StarFix™ Model 4195 Left Ventricular Lead

N/A

Implantable Cardiac Defibrillator, Cardiac Resynchronization Therapy Defibrillator/Pacemaker

Heart Failure

N/A

Clinical Trials (1)

NCT03009175PRoMOTE Follow-up Observational Study

N/A

Pacing Lead

Heart Failure

N/A

Clinical Trials (1)

NCT00927251Model 4296 Left Ventricular (LV) Lead Study

N/A

Catheter Ablation

Atrial Fibrillation

N/A

Clinical Trials (1)

NCT00703157Surgical or Catheter Ablation of Lone Atrial Fibrillation (AF) Patients

N/A

Treatment for intracranial aneurysms

Intracranial Aneurysm

N/A

Clinical Trials (1)

NCT02988128Neurovascular Product Surveillance Registry

N/A

Left Atrial Appendage Occlusion

Atrial Fibrillation

N/A

the coronary sinus balloon pump

STEMI

N/A

Clinical Trials (1)

NCT07082153The First-In-Man Use of Coronary Sinus Balloon Pump in STEMI Patients Treated by Primary PCI

N/A

Melody valve implantation

Right Ventricular Congenital Cardiopathies

N/A

Clinical Trials (1)

NCT02023775Non Interventional Study on Pulmonary Valve Replacement by Thranscatheter Pulmonary Valve Melody™

N/A

Study-required procedures include: tissue collection from device capsule, questionnaire collection, and photo collection

Cardiac Disease

N/A

Clinical Trials (1)

NCT05356546TYRX™ Pocket Health Study

N/A

Reveal LINQ™ Insertable Cardiac Monitor

Stroke, Acute

N/A

Clinical Trials (1)

NCT02700945Rate of Atrial Fibrillation Through 12 Months in Patients With Recent Ischemic Stroke of Presumed Known Origin

N/A

Chronotropic Incompetence Diagnostic Algorithm

Heart Failure

N/A

Clinical Trials (1)

NCT02358603Chronotropic Incompetence (CI) Diagnostic Algorithm in Heart Failure Patients

N/A

Unipolar Polarity Switch Left

Atrial Fibrillation

N/A

Intracardiac electrode catheter

Cardiac Arrhythmias

N/A

Clinical Trials (1)

NCT02326519Electrical Signal Collection From a 20 Pole Catheter During Routine Cardiac Procedures

N/A

Cryoballoon

Persistent Atrial Fibrillation

N/A

Clinical Trials (1)

NCT03706677FIRE AND ICE II Trial Pilot

N/A

LV Lead Extraction

Heart Failure

N/A

Clinical Trials (1)

NCT00893386Attain StarFix® 4195 Lead Extraction Study

N/A

Intravenous caffeine

Atrial Fibrillation

N/A

Cardiac Resynchronization Therapy-Defibrillator

Heart Failure

N/A

Clinical Trials (1)

NCT01045291Pacing for Heart Failure With Preserved Ejection Fraction

N/A

Medtronic Reveal LINQ implantable cardiac monitor

Myocardial Infarction

N/A

Clinical Trials (1)

NCT02594488Implantable Cardiac Monitors in High-Risk Post-Infarction Patients With Cardiac Autonomic Dysfunction

N/A

Left atrial appendage occlusion with the dual mechanism closure Amulet device using a novel steerable sheath.

Atrial Fibrillation

N/A

Bi-plane fluoroscopy

Heart Diseases

N/A

Clinical Trials (1)

NCT03941275SelectSecure 3830 Lead Imaging

N/A

Medtronic Dual-Chamber Pacemaker

Cardiac Pacing, Artificial

N/A

Clinical Trials (1)

NCT00422669Optimize RV Selective Site Pacing Clinical Trial

N/A

Venous Closure

Atrial Fibrillation

N/A

Reveal LINQ™ Insertable Cardiac Monitor with investigational ALLEVIATE-HF RAMware download

Heart Failure NYHA Class II

N/A

Clinical Trials (1)

NCT04452149Algorithm Using LINQ Sensors for Evaluation And Treatment of Heart Failure

N/A

Cardiac Resynchronization Therapy Device

Heart Failure

N/A

Clinical Trials (1)

NCT00291564Ensure Cardiac Resynchronization Therapy Study

N/A

Pacing Lead

Heart Failure

N/A

Clinical Trials (1)

NCT00853593Model 4396 Left Ventricular (LV) Lead Study

N/A

T Wave Alternans Test

Myocardial Infarction

N/A

Clinical Trials (1)

NCT00305214MASTER II - Microvolt T Wave Alternans Testing for Risk Stratification of Post MI Patients

N/A

Defibrillation

Tachyarrhythmia

N/A

Clinical Trials (1)

NCT04863664Lead EvaluAtion for Defibrillation and Reliability (LEADR) / Lead Evaluation for Defibrillation and Reliability in Left Bundle Branch Area Pacing (LEADR LBBAP)

N/A

HeartWare Ventricular Assist Device

Chronic Heart Failure

N/A

Clinical Trials (1)

NCT03697980Apogee, A HeartWare HVAD Destination Product Surveillance Registry (PSR) Platform

N/A

LINQ/LINQ II

Atrial Arrhythmia

N/A

Clinical Trials (1)

NCT05488470QT Changes as Detected From LINQ ECG During Antiarrhythmic Loading (LINQ QT)

N/A

Open Jobs (32)

Interview Prep Quick Facts

Founded: 2024

Portfolio: 1 approved product, 140 clinical trials

Top TAs: Cardiovascular, Metabolic Diseases, Neurology

H-1B (2023): 1 approval

SEC Filings: 2 available

Open Roles: 32 active jobs

Portfolio Health

Peak1 (100%)

1 total products

Therapeutic Area Focus

Cardiovascular

214 pipeline

Metabolic Diseases

1 marketed21 pipeline

8 pipeline

3 pipeline

2 pipeline

1 pipeline

1 pipeline

Marketed

Pipeline

Financials (FY2025)

Revenue

$77M228%

R&D Spend

$135M(174%)24%

Net Income

-$185M

Cash

$89M

Source: SEC 10-K Filing

Hiring Trend

Stable

Open Roles

Added

-0

Filled/Removed

Based on last 4 crawl cycles

Visa Sponsorship

Sponsors Work Visas

H-1B Petitions (FY2023)

Approved

Denied

100%

Rate

Source: USCIS H-1B Employer Data Hub

Rhythm Pharmaceuticals(RYTM)

Products & Portfolio (1)

Pipeline & Clinical Trials

Open Jobs (32)

Manager, Device Quality Assurance

Manager, Supply Chain

Senior Medical Communications Writer - Publications

Payroll Manager

Global Accounts Payable Manager

Regulatory Submission and Project Management Specialist

Global Regulatory Lead

Associate Director, Regulatory Operations

Manager, Operations, Patient Services and Distribution

Territory Manager (Atlanta, GA)

Area Development Manager (West)

Area Development Manager (Southeast)

Area Development Manager (South)

Area Development Manager (Northwest)

Senior National Account Director

Senior Cybersecurity Specialist

Director, IT Business Partner AI &amp; Analytics

Senior Manager, International Market Access

Scientific Affairs Manager, Switzerland

Scientific Affairs Manager, Austria

Scientific Affairs Manager - Germany (Southwest)

Office &amp; Operations Manager, The Netherlands

Medical Director, UK and Ireland

International Brand Manager

Hospital Affairs Lead, Switzerland

Financials (FY2025)

Hiring Trend

Visa Sponsorship

Director, IT Business Partner AI & Analytics

Office & Operations Manager, The Netherlands