Rhythm Pharmaceuticals(RYTM)

BOSTON, MAPharmaceutical1 H-1B visas (FY2023)

Focus: Rhythm Pharmaceuticals is a public biotech focused on peptide therapeutics for neurology, with a peak-stage product (IMCIVREE/setmelanotide) and emerging pipeline in hypothalamic obesity. The company operates at 201–500 employees and generated $77M revenue in FY2025.

Neurology

Profile data last refreshed 8h ago · AI intelligence enriched 1w ago

Funding Stage

PUBLIC

Employees

201-500

Open Jobs

51+7 this month

Growing — net +7 jobs in 30d

27 jobs added vs 20 removed. Steady team buildout.

Should You Work at Rhythm Pharmaceuticals?

AI assessment

Rhythm offers growth-stage opportunity in a focused peptide franchise, but financial model is pre-profitability and pipeline-thin; best for candidates seeking high R&D intensity with IPO-stage upside and tolerance for restructuring risk.

Why Work Here

Public company status with established revenue ($77M FY2025) provides career stability relative to pre-revenue biotech.

Data completeness

7/9 — Strong

Company HealthStrong

Pipeline

Early-stage

50 total

LOE Risk

Protected

No near-term cliffs

Hiring

Stable

Revenue

$77M

Key Products

IMCIVREE

Rare metabolic disorders (MC4R pathway-driven obesity)

Peak7.8yr

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Data Sources

Drug label: DailyMed / FDA
Clinical trials: ClinicalTrials.gov
Patent data: FDA Orange Book
Spending data: CMS Medicare

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.

Pipeline & Clinical Trials

Silverlon®

Infections

N/A

Clinical Trials (1)

NCT02781779Comparison of Outcomes Between the Use of Silverlon® Dressing and AQUACEL® AG Dressing Post Cardiac Device Implant

N/A

Observational

Bradycardia Sinus

N/A

Evera MRI ICD System

Arrhythmias, Cardiac

N/A

Pacemaker lower rate setting

Sinus Node Dysfunction

N/A

prayer

Coronavirus Infection

N/A

Clinical Trials (1)

NCT04361838The COVID-19 ICU PRAYER Study

N/A

Protecta VR-ICD

Tachyarrhythmias

N/A

Reveal® DX or Reveal® XT Insertable Cardiac Monitor

Arrhythmias, Cardiac

N/A

ICD or CRT-D Device

Sudden Cardiac Arrest

N/A

Treatment for intracranial aneurysms

Intracranial Aneurysm

N/A

the coronary sinus balloon pump

STEMI

N/A

Clinical Trials (1)

NCT07082153The First-In-Man Use of Coronary Sinus Balloon Pump in STEMI Patients Treated by Primary PCI

N/A

Melody valve implantation

Right Ventricular Congenital Cardiopathies

N/A

Study-required procedures include: tissue collection from device capsule, questionnaire collection, and photo collection

Cardiac Disease

N/A

Intracardiac electrode catheter

Cardiac Arrhythmias

N/A

Bi-plane fluoroscopy

Heart Diseases

N/A

Medtronic Dual-Chamber Pacemaker

Cardiac Pacing, Artificial

N/A

Defibrillation

Tachyarrhythmia

N/A

LINQ/LINQ II

Atrial Arrhythmia

N/A

Medtronic CoreValve System

Aortic Valve Stenosis

N/A

Medtronic CoreValve System

Severe Aortic Stenosis

N/A

Implantable Cardioverter Defibrillator

Heart Diseases

N/A

MARVEL 2 Algorithm Monitor Mode then Adaptive Mode

Atrioventricular Conduction Block

N/A

Medina Embolization Device In Neurovascular Aneurysm Study

Intracranial Aneurysm

N/A

Transvenous hypoglossal nerve stimulation

Sleep Apnea, Obstructive

N/A

RV lead placement site

Left Ventricular Dysfunction

N/A

Advisa IPG

Bradycardia

N/A

P3: Pacemaker Patient Profiling Study

Bradycardia

N/A

Implanted Device

Tachycardia, Ventricular

N/A

Kansas City Cardiac Dysautonomia Questionnaire

Cardiac Dysautonomia

N/A

Clinical Trials (1)

NCT06672861Development and Validation of the Kansas City Cardiac Dysautonomia Questionnaire (KCDysQ)

N/A

Ventricular Electrical Synchronization by Stimulating Left and Right Bundle Branches Area in Pacing-

Cardiac Pacing

N/A

Evidence based guidelines and tools

Sinus Node Dysfunction

N/A

Out of cathlab insertion

Arrhythmia

N/A

Acute Subcutaneous Defibrillation

Ventricular Arrhythmias

N/A

Full Automaticity and Remote Follow-up

Tachyarrhythmia

N/A

Micra Pacemaker Implant

Class I or II Indication for Implantation of a Single Chamber Ventricular Pacemaker According to ACC/AHA/HRS 2001 Guidelines and Any National Guidelines

N/A

Image Location and Performance of Left Bundle Branch Pacing

Cardiac Pacing

N/A

The coronary sinus balloon pump

STEMI

N/A

Clinical Trials (1)

NCT07354035The Coronary Sinus Balloon Pump in STEMI

N/A

Carelink System

Arrhythmia

N/A

Development of AD/OI after BS

Autonomic Dysfunction

N/A

Clinical Trials (1)

NCT06289413Autonomic Dysfunction in Patients Following Bariatric Surgery: The ADiPOSE Study

N/A

ICD

Ventricular Tachycardia

N/A

High School Students Survey

Sudden Cardiac Arrest

N/A

Clinical Trials (1)

NCT04493970HS Students Mandatory Universal Student Instruction in CPR Appraised Learning- Is the Mandate Working?

N/A

PURE EP

Cardiac Arrhythmias

N/A

Clinical Trials (1)

NCT05450302Assessing the Predictive Value of High Frequency Algorithm of PURE EP for Low Amplitude Signal Detection

N/A

EASE MITRAL Expertise-based Assessment Study on Clinical Efficacy of Profile 3D in MITRAL Valve Annu

Mitral Valve Insufficiency

N/A

Medtronic Engager Transcatheter Aortic Valve Implantation System

Aortic Valve Stenosis

N/A

Defibrillation using the Extravascular ICD

Tachycardia

N/A

INDIcators for Clarifying the bAckground of exTreme Obesity in childRen

Gene Abnormality

N/A

Clinical Trials (1)

NCT06420622INDIcators for Clarifying the bAckground of exTreme Obesity in childRen

N/A

Implantable Pulse Generators

Sick Sinus Syndrome

N/A

Melody Transcatheter Pulmonary Valve

Heart Valve Diseases

N/A

Non-slip Balloon Catheter of Shanghai MicroPort Rhythm

Coronary Artery Stenosis

N/A

Clinical Trials (1)

NCT05606367Coronary Non-slip Balloon Catheter in Patients With Coronary Artery Stenosis(CREST)

N/A

CoreValve Advance-II Study: Prospective International Post-market Study

Aortic Valve Stenosis

N/A

Single Chamber Implantable Cardioverter Defibrillator

Ventricular Tachycardia

N/A

Interview Prep Quick Facts

Founded: 2024

Portfolio: 1 approved product, 98 clinical trials

Top TAs: Cardiovascular, Metabolic Diseases, Neurology

H-1B (2023): 1 approval

Publications: 26 in PubMed

SEC Filings: 2 available

Open Roles: 51 active jobs

Portfolio Health

Peak1 (100%)

1 total products

Therapeutic Area Focus

Cardiovascular

40 pipeline

Metabolic Diseases

1 marketed24 pipeline

Neurology

6 pipeline

Endocrinology

1 pipeline

Nephrology

1 pipeline

Financials (FY2025)

Revenue

$77M228%

R&D Spend

$135M(174%)24%

Net Income

-$185M

Hiring Trend

Stable

Open Roles

Added

-2

Filled/Removed

Based on last 4 crawl cycles

Visa Sponsorship

Sponsors Work Visas

H-1B Petitions (FY2023)

Approved

Denied

100%

Rate

Source: USCIS H-1B Employer Data Hub

Research Publications(10)

Recent peer-reviewed publications with author affiliations at this company

Setmelanotide for the Treatment of Acquired Hypothalamic Obesity.

The New England journal of medicine

2026

PMID:42418774

Setmelanotide in Bardet-Biedl Syndrome: A 52-Week Comparison of Phase 3 Trial Participants With a Matched Registry Cohort.

Rhythm Pharmaceuticals(RYTM)

Should You Work at Rhythm Pharmaceuticals?

Why Work Here

Key Products

Watch Out For

Products & Portfolio (1)

Pipeline & Clinical Trials

Recent News · Rhythm Pharmaceuticals(10)

Open Jobs (51)

Senior Manager, Quality Assurance/Qualified Person

Associate Director, Safety Science

Hospital Affairs Lead, Austria

Director, HR Business Partner, International

(Senior) Brand Manager, Iberia

Medical Science Liaison Director, West Region (Dallas)

Medical Science Liaison Director, East Region (Atlanta)

Territory Manager, aHO (Minneapolis)

Scientific Affairs Manager - Germany (North East)

Senior Publications Manager

Senior Payroll Specialist, International

Medical Science Liaison (Senior Manager, Field Medical) - South Central

Medical Science Liaison (Senior Manager, Field Medical) - South

Medical Science Liaison (Senior Manager, Field Medical) - PA/Upstate NY

Medical Science Liaison (Senior Manager, Field Medical) - Northwest

Medical Science Liaison (Senior Manager, Field Medical) - New York Metro

Senior Statistical Programmer

Senior Manager, Drug Substance

Territory Manager, BBS (Florida)

Territory Manager (Eastern Canada)

Hospital Affairs Director, Germany

Associate Director, Biostatistics

Senior Director, Biostatistics

Senior Manager, Analytical Chemistry

Senior Manager, Compensation

Financials (FY2025)

Hiring Trend

Visa Sponsorship

Research Publications(10)