Severe Aortic Stenosis

Cardiovascular
0
Pipeline Programs
3
Companies
4
Clinical Trials
2 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

3 companies ranked by most advanced pipeline stage

Colibri Heart Valve
Colibri Heart ValveCO - Louisville
1 program
Colibri TAVI SystemN/A1 trial
Active Trials
NCT04029844RecruitingEst. Jul 2028
Rhythm Pharmaceuticals
1 program
Medtronic CoreValve SystemN/A1 trial
Active Trials
NCT01074658Completed1,015Est. May 2017
Abbott
AbbottABBOTT PARK, IL
1 program
Navitor Transcatheter Aortic Valve ImplantationN/A2 trials
Active Trials
NCT07193888Recruiting100Est. Mar 2027
NCT05932615Enrolling By Invitation1,500Est. Apr 2036

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
2030
2031
AbbottNavitor Transcatheter Aortic Valve Implantation
AbbottNavitor Transcatheter Aortic Valve Implantation
Colibri Heart ValveColibri TAVI System
Rhythm PharmaceuticalsMedtronic CoreValve System

Clinical Trials (4)

Total enrollment: 2,615 patients across 4 trials

NCT07193888AbbottNavitor Transcatheter Aortic Valve Implantation

Navitor Japan Study

Start: Oct 2025Est. completion: Mar 2027100 patients
N/ARecruiting
NCT05932615AbbottNavitor Transcatheter Aortic Valve Implantation

ENVISION IDE Trial: Safety and Effectiveness of NAVITOR in Transcatheter Aortic Valve Implantation

Start: Mar 2024Est. completion: Apr 20361,500 patients
N/AEnrolling By Invitation
NCT04029844Colibri Heart ValveColibri TAVI System

Colibri Transcatheter Aortic Heart Valve System Study

Start: Sep 2021Est. completion: Jul 2028
N/ARecruiting
NCT01074658Rhythm PharmaceuticalsMedtronic CoreValve System

CoreValve Advance International Post Market Study

Start: Mar 2010Est. completion: May 20171,015 patients
N/ACompleted

Related Jobs in Cardiovascular

Embedded Software and System Test Engineer (H/F)

Cardiawave
Levallois-Perret, France (Hybrid)
Just now

Territory Sales Manager - Iowa / Nebraska

HeartFlow
Cedar Rapids, IA; Des Moines, IA; Omaha, NE; Lincoln, NE
Yesterday
From $150K/yr

Associate Regulatory Affairs Specialist

Medtronic
Mounds View, Minnesota, United States of America
Yesterday
$60K - $90K/yr

Business Development Manager, Post Transplant, Cardio Thoracic

Thermo Fisher Scientific
Remote
Yesterday

Director, Medical Affairs

Abbott
Germany - Hesse - Eschborn
Yesterday

Therapy Development Manager

Abbott
Australia > Doncaster : 666 Doncaster Road
Yesterday

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

2 actively recruiting trials targeting 2,615 patients
3 companies competing in this space

Related Indications

Heart Failure(334)Hypertension(333)Coronary Artery Disease(295)Atrial Fibrillation(288)Pulmonary Arterial Hypertension(103)Acute Coronary Syndrome(62)Pulmonary Hypertension(55)Essential Hypertension(32)Coronary Heart Disease(28)Aortic Valve Stenosis(27)