Intracranial Aneurysm

0
Pipeline Programs
5
Companies
11
Clinical Trials
3 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

5 companies ranked by most advanced pipeline stage

BALT
BALTCA - Irvine
5 programs
BALT medical devicesN/A1 trial
Intracranial aneurysm treated with Silk vista and silk vista babyN/A1 trial
LEO +N/A1 trial
OPTIMA and OPTIMAX Coils manufactured by Balt USAN/A1 trial
intracranial aneurysm coilingN/A1 trial
Active Trials
NCT04927156Recruiting10,000Est. Oct 2041
NCT04034810Active Not Recruiting234Est. Nov 2027
NCT03504436Completed176Est. Jan 2019
+2 more trials
Rhythm Pharmaceuticals
3 programs
Medina Embolization Device In Neurovascular Aneurysm StudyN/A1 trial
Pipeline™ Flex Embolization Device with Shield Technology™N/A1 trial
Treatment for intracranial aneurysmsN/A1 trial
Active Trials
NCT02982200TerminatedEst. Oct 2018
NCT02719522Completed205Est. Aug 2019
NCT02988128RecruitingEst. Aug 2032
Spryte Medical
Spryte MedicalMA - Bedford
1 program
Endovascular Intracranial aneurysm treatmentN/A1 trial
Active Trials
NCT07214220Not Yet RecruitingEst. Feb 2029
City Therapeutics
City TherapeuticsMA - Cambridge
1 program
NCVC-CS1N/A1 trial
Active Trials
NCT02907229CompletedEst. Mar 2019
Penumbra
PenumbraALAMEDA, CA
1 program
Penumbra Smart CoilN/A1 trial
Active Trials
NCT02729740Completed995Est. Dec 2019

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
2030
2031
Spryte MedicalEndovascular Intracranial aneurysm treatment
BALTOPTIMA and OPTIMAX Coils manufactured by Balt USA
BALTBALT medical devices
BALTIntracranial aneurysm treated with Silk vista and silk vista baby
BALTintracranial aneurysm coiling
Rhythm PharmaceuticalsMedina Embolization Device In Neurovascular Aneurysm Study
Rhythm PharmaceuticalsTreatment for intracranial aneurysms
PenumbraPenumbra Smart Coil
City TherapeuticsNCVC-CS1
Rhythm PharmaceuticalsPipeline™ Flex Embolization Device with Shield Technology™
BALTLEO +

Clinical Trials (11)

Total enrollment: 11,910 patients across 11 trials

NCT07214220Spryte MedicalEndovascular Intracranial aneurysm treatment

Intravascular Neuro OCT Imaging System for Aneurysm Treatment Evaluation

Start: Feb 2026Est. completion: Feb 2029
N/ANot Yet Recruiting
NCT06282939BALTOPTIMA and OPTIMAX Coils manufactured by Balt USA

Optima Coil Performance in The Interventional Management of Intracranial Aneurysms Registry

Start: Nov 2023Est. completion: Dec 2027
N/ARecruiting
NCT04927156BALTBALT medical devices

Safety, Performance and Usability of BALT Medical Devices: The EVIDENCE Post Marketing Clinical Follow-up Platform

Start: Jul 2021Est. completion: Oct 204110,000 patients
N/ARecruiting
NCT04034810BALTIntracranial aneurysm treated with Silk vista and silk vista baby

Safety and Efficacy of Silk Vista and Silk Vista Baby Flow Diverter for Intracranial Aneurysm Treatment

Start: Nov 2019Est. completion: Nov 2027234 patients
N/AActive Not Recruiting
NCT03642821BALTintracranial aneurysm coiling

Intracranial Aneurysms Treatment With the OPTIMA Coil System

Start: Mar 2019Est. completion: Feb 2023300 patients
N/ACompleted
NCT02982200Rhythm PharmaceuticalsMedina Embolization Device In Neurovascular Aneurysm Study

Medina Embolization Device In Neurovascular Aneurysm Study

Start: Dec 2016Est. completion: Oct 2018
N/ATerminated
NCT02988128Rhythm PharmaceuticalsTreatment for intracranial aneurysms

Neurovascular Product Surveillance Registry

Start: Dec 2016Est. completion: Aug 2032
N/ARecruiting
NCT02729740PenumbraPenumbra Smart Coil

Assessment of the Embolization of Neurovascular Lesions Using the Penumbra Smart Coil

Start: Jun 2016Est. completion: Dec 2019995 patients
N/ACompleted
NCT02907229City TherapeuticsNCVC-CS1

Safety and Efficacy of Honeycomb Microporous Covered Stents (NCVC-CS1) for the Treatment of Intracranial Aneurysms

Start: May 2016Est. completion: Mar 2019
N/ACompleted
NCT02719522Rhythm PharmaceuticalsPipeline™ Flex Embolization Device with Shield Technology™

Pipeline Flex With SHield Technology Embolization - An International MulticEnter ObservationaL Post Market StuDy

Start: Mar 2016Est. completion: Aug 2019205 patients
N/ACompleted
NCT03504436BALTLEO +

Endovascular Treatment of Wide Neck Intracranial Aneurysms With the LEO + Stent : The LEO + II Cohort Study

Start: Mar 2015Est. completion: Jan 2019176 patients
N/ACompleted

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

3 actively recruiting trials targeting 11,910 patients
5 companies competing in this space