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Cardiac Disease

3
Pipeline Programs
18
Companies
18
Clinical Trials
3 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
1
0
0
2
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

13 companies ranked by most advanced pipeline stage

Syneos Health
Syneos HealthNC - Morrisville
2 programs
2
DEFINITYPhase 31 trial
DEFINITY®Phase 31 trial
Active Trials
NCT03571672Completed153Est. Aug 2019
NCT03719612Completed160Est. Jan 2020
Biocorp
BiocorpFrance - Issoire
3 programs
1
NH002Phase 1/21 trial
PARASTERNAL BLOCKN/A1 trial
Parasternal Block+ Infiltration with local anesthetic of access to thoracic drainageN/A1 trial
Active Trials
NCT05764616Completed58Est. Nov 2023
NCT04319588Completed126Est. May 2020
NCT04185246Completed36Est. Jul 2020
Sensydia
SensydiaCA - Los Angeles
3 programs
Cardiac Performance SystemN/A1 trial
Cardiac Performance SystemN/A1 trial
Cardiac Performance SystemN/A1 trial
Active Trials
NCT04131725Completed275Est. Apr 2023
NCT06149143Unknown50Est. Jun 2024
NCT05866666Unknown115Est. May 2024
Elutia
ElutiaSILVER SPRING, MD
2 programs
CIED envelopeN/A1 trial
CanGaroo EnvelopeN/A1 trial
Active Trials
NCT04645173Completed46Est. Dec 2023
NCT04351269Completed597Est. Jun 2021
Biotronik
BiotronikGermany - Berlin
2 programs
Lumax DX / Linox DX EvaluationN/A1 trial
Setrox JS Master StudyN/A1 trial
Active Trials
NCT01486836Completed38Est. Sep 2012
NCT01487941Completed66Est. Oct 2014
Lantheus Medical Imaging
2 programs
DEFINITYPHASE_3
DEFINITY®PHASE_3
Medtronic
MedtronicNJ - Phillipsburg
1 program
CT Data Collection StudyN/A1 trial
Active Trials
NCT03589664Completed100Est. Dec 2019
Rhythm Pharmaceuticals
1 program
CT Data Collection StudyN/A
Unimed Pharma
Unimed PharmaSlovakia - Bratislava
1 program
Coronary artery bypass graftN/A1 trial
Active Trials
NCT06179329Recruiting150Est. Dec 2027
Dexcom
DexcomCA - San Diego
1 program
Dexcom G6N/A1 trial
Active Trials
NCT06275971Unknown68Est. Aug 2024
Colorado Therapeutics
Colorado TherapeuticsCO - Louisville
1 program
Fresh Autologous whole BloodN/A1 trial
Active Trials
NCT03204357Recruiting70Est. Sep 2026
Boston Scientific
Boston ScientificCA - Valencia
1 program
ImplantN/A1 trial
Active Trials
NCT04823663Recruiting12,500Est. Dec 2030
Abbott
AbbottABBOTT PARK, IL
1 program
cardiovascular implantable electronic devicesN/A1 trial
Active Trials
NCT06595615Enrolling By Invitation80Est. Dec 2027

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
2030
Syneos HealthDEFINITY®
Syneos HealthDEFINITY
BiocorpNH002
Abbottcardiovascular implantable electronic devices
Unimed PharmaCoronary artery bypass graft
SensydiaCardiac Performance System
SensydiaCardiac Performance System
BiocorpPARASTERNAL BLOCK
DexcomDexcom G6
Colorado TherapeuticsFresh Autologous whole Blood
Boston ScientificImplant
ElutiaCIED envelope
SensydiaCardiac Performance System
ElutiaCanGaroo Envelope
BiocorpParasternal Block+ Infiltration with local anesthetic of access to thoracic drainage

Showing 15 of 18 trials with date data

Clinical Trials (18)

Total enrollment: 14,688 patients across 18 trials

NCT03719612Syneos HealthDEFINITY®

DEF-315 Better Accuracy in Ejection Fraction (EF) Assessment With DEFINITY

Start: Dec 2018Est. completion: Jan 2020160 patients
Phase 3Completed
NCT03571672Syneos HealthDEFINITY

DEF-314 Better Accuracy in Ejection Fraction (EF) Assessment With DEFINITY

Start: Oct 2018Est. completion: Aug 2019153 patients
Phase 3Completed
NCT04185246BiocorpNH002

A Dose Ascending Study to Evaluate the Safety of NH002 as a Contrast Agent in Cardiac Echocardiography

Start: Nov 2019Est. completion: Jul 202036 patients
Phase 1/2Completed
NCT06595615Abbottcardiovascular implantable electronic devices

Health App Data Collection Study

Start: Apr 2025Est. completion: Dec 202780 patients
N/AEnrolling By Invitation
NCT06179329Unimed PharmaCoronary artery bypass graft

One-year Patency Comparison Between Radial Artery and No-touch Saphenous Vein Grafts in Women Undergoing Isolated CABG

Start: Jan 2024Est. completion: Dec 2027150 patients
N/ARecruiting
NCT06149143SensydiaCardiac Performance System

Cardiac Performance System Data Collection Study - Minnesota

Start: Oct 2023Est. completion: Jun 202450 patients
N/AUnknown
NCT05866666SensydiaCardiac Performance System

Cardiac Performance System Data Collection Study

Start: May 2023Est. completion: May 2024115 patients
N/AUnknown
NCT05764616BiocorpPARASTERNAL BLOCK

Parasternal Block Combined With Rectus Sheath Block for Cardiac Surgery Under Sternotomy

Start: Mar 2023Est. completion: Nov 202358 patients
N/ACompleted
NCT06275971DexcomDexcom G6

Effectiveness of Continuous Glucose Monitoring System Among Cardiac Surgery Patients

Start: Nov 2022Est. completion: Aug 202468 patients
N/AUnknown
NCT03204357Colorado TherapeuticsFresh Autologous whole Blood

Fresh Autologous Whole Blood Transfusion After Cardiopulmonary Bypass

Start: Jan 2022Est. completion: Sep 202670 patients
N/ARecruiting
NCT04823663Boston ScientificImplant

BoStOn SCientific Rhythm MAnagemenT REgiStry (SOCRATES)

Start: Mar 2021Est. completion: Dec 203012,500 patients
N/ARecruiting
NCT04645173ElutiaCIED envelope

Comparison of Participants Who Received a CanGaroo® Envelope, TYRX™ Envelope, or no Envelope During CIED Implantation

Start: Feb 2021Est. completion: Dec 202346 patients
N/ACompleted
NCT04131725SensydiaCardiac Performance System

Cardiac Function Non-Invasive Monitoring System Evaluation Trial

Start: Nov 2020Est. completion: Apr 2023275 patients
N/ACompleted
NCT04351269ElutiaCanGaroo Envelope

Retrospective Experience Of CIED Implantation

Start: Apr 2020Est. completion: Jun 2021597 patients
N/ACompleted
NCT04319588BiocorpParasternal Block+ Infiltration with local anesthetic of access to thoracic drainage

Parasternal Block for Cardiac Surgery

Start: Mar 2020Est. completion: May 2020126 patients
N/ACompleted
NCT03589664MedtronicCT Data Collection Study

CT Data Collection Study

Start: Jul 2018Est. completion: Dec 2019100 patients
N/ACompleted
NCT01487941BiotronikSetrox JS Master Study

Setrox JS Master Study

Start: Dec 2011Est. completion: Oct 201466 patients
N/ACompleted
NCT01486836BiotronikLumax DX / Linox DX Evaluation

Lumax DX / Linox DX Evaluation

Start: Nov 2011Est. completion: Sep 201238 patients
N/ACompleted

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

2 late-stage (Phase 3) programs, potential near-term approvals
3 actively recruiting trials targeting 14,688 patients
18 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.