Cardiac Disease

2
Pipeline Programs
6
Companies
11
Clinical Trials
1 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
2
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

6 companies ranked by most advanced pipeline stage

Lantheus Medical Imaging
2 programs
2
DEFINITYPhase 31 trial
DEFINITY®Phase 31 trial
Active Trials
NCT03571672CompletedEst. Aug 2019
NCT03719612CompletedEst. Jan 2020
Sensydia
SensydiaCA - Los Angeles
3 programs
Cardiac Performance SystemN/A1 trial
Cardiac Performance SystemN/A1 trial
Cardiac Performance SystemN/A1 trial
Active Trials
NCT06149143Recruiting50Est. Jun 2024
NCT05866666Unknown115Est. May 2024
NCT04131725Completed275Est. Apr 2023
Elutia
ElutiaSILVER SPRING, MD
2 programs
CIED envelopeN/A1 trial
CanGaroo EnvelopeN/A1 trial
Active Trials
NCT04645173CompletedEst. Dec 2023
NCT04351269CompletedEst. Jun 2021
Biotronik
BiotronikGermany - Berlin
2 programs
Lumax DX / Linox DX EvaluationN/A1 trial
Setrox JS Master StudyN/A1 trial
Active Trials
NCT01486836Completed38Est. Sep 2012
NCT01487941Completed66Est. Oct 2014
Rhythm Pharmaceuticals
1 program
CT Data Collection StudyN/A1 trial
Active Trials
NCT03589664Completed100Est. Dec 2019
Abbott
AbbottABBOTT PARK, IL
1 program
cardiovascular implantable electronic devicesN/A1 trial
Active Trials
NCT06595615Not Yet Recruiting80Est. Dec 2027

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
Lantheus Medical ImagingDEFINITY®
Lantheus Medical ImagingDEFINITY
Abbottcardiovascular implantable electronic devices
SensydiaCardiac Performance System
SensydiaCardiac Performance System
ElutiaCIED envelope
SensydiaCardiac Performance System
ElutiaCanGaroo Envelope
Rhythm PharmaceuticalsCT Data Collection Study
BiotronikSetrox JS Master Study
BiotronikLumax DX / Linox DX Evaluation

Clinical Trials (11)

Total enrollment: 724 patients across 11 trials

NCT03719612Lantheus Medical ImagingDEFINITY®

DEF-315 Better Accuracy in Ejection Fraction (EF) Assessment With DEFINITY

Start: Dec 2018Est. completion: Jan 2020
Phase 3Completed
NCT03571672Lantheus Medical ImagingDEFINITY

DEF-314 Better Accuracy in Ejection Fraction (EF) Assessment With DEFINITY

Start: Oct 2018Est. completion: Aug 2019
Phase 3Completed
NCT06595615Abbottcardiovascular implantable electronic devices

Health App Data Collection Study

Start: Mar 2025Est. completion: Dec 202780 patients
N/ANot Yet Recruiting
NCT06149143SensydiaCardiac Performance System

Cardiac Performance System Data Collection Study - Minnesota

Start: Oct 2023Est. completion: Jun 202450 patients
N/ARecruiting
NCT05866666SensydiaCardiac Performance System

Cardiac Performance System Data Collection Study

Start: May 2023Est. completion: May 2024115 patients
N/AUnknown
NCT04645173ElutiaCIED envelope

Comparison of Participants Who Received a CanGaroo® Envelope, TYRX™ Envelope, or no Envelope During CIED Implantation

Start: Feb 2021Est. completion: Dec 2023
N/ACompleted
NCT04131725SensydiaCardiac Performance System

Cardiac Function Non-Invasive Monitoring System Evaluation Trial

Start: Nov 2020Est. completion: Apr 2023275 patients
N/ACompleted
NCT04351269ElutiaCanGaroo Envelope

Retrospective Experience Of CIED Implantation

Start: Apr 2020Est. completion: Jun 2021
N/ACompleted
NCT03589664Rhythm PharmaceuticalsCT Data Collection Study

CT Data Collection Study

Start: Jul 2018Est. completion: Dec 2019100 patients
N/ACompleted
NCT01487941BiotronikSetrox JS Master Study

Setrox JS Master Study

Start: Dec 2011Est. completion: Oct 201466 patients
N/ACompleted
NCT01486836BiotronikLumax DX / Linox DX Evaluation

Lumax DX / Linox DX Evaluation

Start: Nov 2011Est. completion: Sep 201238 patients
N/ACompleted

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

2 late-stage (Phase 3) programs — potential near-term approvals
1 actively recruiting trials targeting 724 patients
6 companies competing in this space