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Left Ventricular Dysfunction

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Pipeline Programs
7
Companies
8
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
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Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

5 companies ranked by most advanced pipeline stage

Eko Devices
Eko DevicesCA - Emeryville
4 programs
Use of Eko DUO Electronic StethoscopeN/A1 trial
Use of Eko DUO electronic StethoscopeN/A1 trial
Use of Eko DUO electronic stethoscopeN/A1 trial
Use of Eko DUO electronic stethoscopeN/A1 trial
Active Trials
NCT05010655Completed1,935Est. May 2022
NCT05010642Completed307Est. Apr 2022
NCT04933890Completed68Est. Dec 2021
+1 more trials
Medtronic
MedtronicNJ - Phillipsburg
2 programs
Left ventricular septum pacing leadN/A
RV lead placement siteN/A
Rhythm Pharmaceuticals
2 programs
Left ventricular septum pacing leadN/A1 trial
RV lead placement siteN/A1 trial
Active Trials
NCT01609738Completed12Est. Feb 2015
NCT00461734Completed248Est. Sep 2015
Boston Scientific
Boston ScientificCA - Valencia
1 program
CRT-DN/A1 trial
Active Trials
NCT03257436Completed586Est. Nov 2020
Cordis
CordisFL - Miami Lakes
1 program
PCIPHASE_31 trial
Active Trials
NCT00938847Completed20Est. Oct 2008

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
CordisPCI
Eko DevicesUse of Eko DUO electronic Stethoscope
Eko DevicesUse of Eko DUO electronic stethoscope
Eko DevicesUse of Eko DUO Electronic Stethoscope
Eko DevicesUse of Eko DUO electronic stethoscope
Boston ScientificCRT-D
Rhythm PharmaceuticalsLeft ventricular septum pacing lead
Rhythm PharmaceuticalsRV lead placement site

Clinical Trials (8)

Total enrollment: 4,434 patients across 8 trials

NCT00938847CordisPCI

Bone Marrow Derived Mononuclear Cells For Myocardial Regeneration

Start: Feb 2006Est. completion: Oct 200820 patients
Phase 3Completed
NCT05010642Eko DevicesUse of Eko DUO electronic Stethoscope

Low Ejection Fraction in Single Lead ECG- Ochsner

Start: Aug 2021Est. completion: Apr 2022307 patients
N/ACompleted
NCT04933890Eko DevicesUse of Eko DUO electronic stethoscope

Detection of Heart Conditions Using Artificial Intelligence

Start: Jun 2021Est. completion: Dec 202168 patients
N/ACompleted
NCT05010655Eko DevicesUse of Eko DUO Electronic Stethoscope

Low Ejection Fraction in Single Lead ECG

Start: Jun 2021Est. completion: May 20221,935 patients
N/ACompleted
NCT04400435Eko DevicesUse of Eko DUO electronic stethoscope

Detection of Heart Conditions With Single Lead ECG Using Artificial Intelligence

Start: Jul 2020Est. completion: Apr 20221,258 patients
N/ACompleted
NCT03257436Boston ScientificCRT-D

Strategic Management to Improve CRT Using Multi-Site Pacing Post Approval Study (Reference # C1918)

Start: Jan 2018Est. completion: Nov 2020586 patients
N/ACompleted
NCT01609738Rhythm PharmaceuticalsLeft ventricular septum pacing lead

Left Ventricular Septum Pacing in Patients by Transvenous Approach Through the Inter-ventricular Septum

Start: Nov 2012Est. completion: Feb 201512 patients
N/ACompleted
NCT00461734Rhythm PharmaceuticalsRV lead placement site

PROTECT-PACE STUDY - The Protection of Left Ventricular Function During Right Ventricular Pacing

Start: Aug 2007Est. completion: Sep 2015248 patients
N/ACompleted

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

7 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.