Left Ventricular Dysfunction

1
Pipeline Programs
3
Companies
7
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
1
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

3 companies ranked by most advanced pipeline stage

C
CordisFL - Miami Lakes
1 program
1
PCIPhase 31 trial
Active Trials
NCT00938847Completed20Est. Oct 2008
Eko Devices
Eko DevicesCA - Emeryville
4 programs
Use of Eko DUO Electronic StethoscopeN/A1 trial
Use of Eko DUO electronic StethoscopeN/A1 trial
Use of Eko DUO electronic stethoscopeN/A1 trial
Use of Eko DUO electronic stethoscopeN/A1 trial
Active Trials
NCT05010655Completed1,935Est. May 2022
NCT05010642Completed307Est. Apr 2022
NCT04400435Completed1,258Est. Apr 2022
+1 more trials
Rhythm Pharmaceuticals
2 programs
Left ventricular septum pacing leadN/A1 trial
RV lead placement siteN/A1 trial
Active Trials
NCT01609738CompletedEst. Feb 2015
NCT00461734Completed248Est. Sep 2015

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
CordisPCI
Eko DevicesUse of Eko DUO electronic Stethoscope
Eko DevicesUse of Eko DUO electronic stethoscope
Eko DevicesUse of Eko DUO Electronic Stethoscope
Eko DevicesUse of Eko DUO electronic stethoscope
Rhythm PharmaceuticalsLeft ventricular septum pacing lead
Rhythm PharmaceuticalsRV lead placement site

Clinical Trials (7)

Total enrollment: 3,836 patients across 7 trials

NCT00938847CordisPCI

Bone Marrow Derived Mononuclear Cells For Myocardial Regeneration

Start: Feb 2006Est. completion: Oct 200820 patients
Phase 3Completed
NCT05010642Eko DevicesUse of Eko DUO electronic Stethoscope

Low Ejection Fraction in Single Lead ECG- Ochsner

Start: Aug 2021Est. completion: Apr 2022307 patients
N/ACompleted
NCT04933890Eko DevicesUse of Eko DUO electronic stethoscope

Detection of Heart Conditions Using Artificial Intelligence

Start: Jun 2021Est. completion: Dec 202168 patients
N/ACompleted
NCT05010655Eko DevicesUse of Eko DUO Electronic Stethoscope

Low Ejection Fraction in Single Lead ECG

Start: Jun 2021Est. completion: May 20221,935 patients
N/ACompleted
NCT04400435Eko DevicesUse of Eko DUO electronic stethoscope

Detection of Heart Conditions With Single Lead ECG Using Artificial Intelligence

Start: Jul 2020Est. completion: Apr 20221,258 patients
N/ACompleted
NCT01609738Rhythm PharmaceuticalsLeft ventricular septum pacing lead

Left Ventricular Septum Pacing in Patients by Transvenous Approach Through the Inter-ventricular Septum

Start: Nov 2012Est. completion: Feb 2015
N/ACompleted
NCT00461734Rhythm PharmaceuticalsRV lead placement site

PROTECT-PACE STUDY - The Protection of Left Ventricular Function During Right Ventricular Pacing

Start: Aug 2007Est. completion: Sep 2015248 patients
N/ACompleted

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

1 late-stage (Phase 3) programs — potential near-term approvals
3 companies competing in this space