Patent Cliff Hiring Radar
Drugs losing exclusivity in the next 24 months, ranked by hiring velocity at the affected companies. The thesis: pharma companies hire ahead of patent cliffs to launch lifecycle-extension follow-ons, defend share, and transition reps to other portfolio drugs. A “Hot” company about to lose exclusivity is the most actionable career signal we surface.
100 branded drugs with LOE dates within 24 months · sorted by hiring velocity then by months-to-cliff
Cliff within 12 months
Most-time-sensitive — companies under active hiring pressure tend to be here.
PNAC
Seasonal Allergic Rhinitis
Inguinal Hernia
these symptoms associated with hay fever, other upper respiratory allergies, the common cold: runny nose itchy +3
Diabetic Peripheral Neuropathic Pain, Postherpetic Neuralgia, Epilepsy +1
Influenza
Phenylketonuria
Epilepsy, Partial-Onset Seizures, Generalized Tonic-Clonic Seizures +1
Epilepsy, Partial-Onset Seizures, Generalized Tonic-Clonic Seizures +1
Migraine, Migraine Without Aura
Pulmonary Hypertension
Post-Operative Pain, Ankle Sprain
Pain, Low Back Pain, Osteoarthritis
Pain, Low Back Pain, Osteoarthritis
Nitroimidazole Antimicrobial [EPC]
pseudobulbar affect (PBA)
Basal Cell Carcinoma
Hypogonadism
Acne Vulgaris, Bacterial Vaginosis
Ulcerative Colitis, Inflammatory Bowel Disease
Acute Ischemic Stroke, Rosacea, Peripheral Neuropathy +3
Epilepsy
including term, preterm neonates, a source of calories +4
bacteria
bacteria
bacteria
Pneumonia, Otitis Media, Sinusitis +9
Male Hypogonadism
12 to 24 months out
Earlier signal — lifecycle-extension hiring usually kicks in here.
Ulcerative Colitis, Crohn's Disease, Proctitis
Ulcerative Colitis, Crohn's Disease
Gastroesophageal Reflux Disease, Gastric Ulcer, Duodenal Ulcer
Substance P/Neurokinin-1 Receptor Antagonist [EPC]
Chemotherapy-Induced Nausea and Vomiting, Postoperative Nausea and Vomiting
Histone Deacetylase Inhibitor [EPC]
Ethylene Glycol Poisoning, Methanol Poisoning
Migraine, Migraine with Aura
Surgical Site Infection, Healthcare-Associated Infection
Allergic Rhinitis, Urticaria
Epilepsy, Seizures
Methodology: LOE (loss of exclusivity) dates come from FDA Orange Book patent + exclusivity records, taking the earlier of the two. Hiring velocity is computed from CrawlRun deltas over the last 30 days (jobs created − jobs removed) at the company level. “Hot” ≥ +20, “Growing” ≥ +5, “Stable” ±5, “Cooling” ≤ −5, “Contracting” ≤ −20. Patent cliffs are not financial advice; companies adjust hiring for many reasons beyond exclusivity loss.