BRIDION

LOE Approaching

sugammadex

NDAINTRAVENOUSSOLUTIONPriority Review
Approved
Dec 2015
Lifecycle
LOE Approaching
Competitive Pressure
15/100
Clinical Trials
20

Mechanism of Action

cyclodextrin. It forms a complex with the neuromuscular blocking agents rocuronium and vecuronium, and it reduces the amount of neuromuscular blocking agent available to bind to nicotinic cholinergic receptors in the neuromuscular junction. This results in the reversal of neuromuscular blockade…

Clinical Trials (5)

NCT06623370Phase 4Completed

The Effect of Methylprednisolone on the Reversal Time of Rocuronium by Sugammadex in the Pediatric Patient Group

Started Oct 2024
NCT06136585Phase 3Recruiting

Sugammadex Vs Neostigmine in Reversing Neuromuscular Blocks in Outpatient ERCP. A Randomized, Double-Blinded Trial

Started Jun 2024
80 enrolled
Neuromuscular Blocks
NCT05887375Phase 4Enrolling By Invitation

Sugammadex vs Neostigmine/Glycopyrrolate on Urinary Retention After Spine Surgery

Started Aug 2023
118 enrolled
Spine SurgeryReversal of Neuromuscular BlockadeUrinary Retention Postoperative
NCT05661409Phase 4Completed

Sugammadex as Rescue Therapy

Started Jul 2023
46 enrolled
Neuromuscular Blockade
NCT04606901Phase 4Completed

Comparison of Time to Extubation Using Sugammadex or Neostigmine

Started Apr 2021
58 enrolled
Neuromuscular BlockadeChronic Obstructive Pulmonary Disease

Loss of Exclusivity

LOE Date
Dec 12, 2027
21 months away
Patent Expiry
Jul 27, 2026
Exclusivity Expiry
Jun 12, 2028

Patent Records (2)

Patent #ExpiryTypeUse Code
RE44733
Jan 27, 2026Expired
SubstanceProduct
U-1794
RE44733*PED
Jul 27, 2026