NDAINTRAVENOUSSOLUTION
Approved
Dec 2014
Lifecycle
LOE Approaching
Competitive Pressure
25/100
Clinical Trials
15
Data completeness
4/8 — Partial
RAPIVAB (peramivir) by BioCryst Pharmaceuticals is neuraminidase inhibitors [moa]. First approved in 2014.
Drug data last refreshed 17h ago · AI intelligence enriched 4d ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
RAPIVAB (peramivir) is an intravenous neuraminidase inhibitor antiviral approved in December 2014 for treatment of acute influenza. It works by inhibiting viral neuraminidase, preventing influenza virus release from infected cells. It is indicated for patients with acute uncomplicated influenza infection.
LOE Approaching7mo to LOE
Product faces imminent loss of exclusivity in mid-2027 with modest competitive pressure (25%), signaling consolidation or transition planning for commercial teams.
Mechanism of Action
Neuraminidase Inhibitors
Pharmacologic Class:
Neuraminidase Inhibitor
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (15)
Safety, PK and Effectiveness of IV Peramivir in Elderly and Higher Risk Subjects With Uncomplicated Influenza
Started Dec 2015
74 enrolled
Influenza
ED Influenza Therapeutic Pilot Study: Oseltamivir vs. Peramivir
Started Nov 2015
180 enrolled
Influenza
Safety, PK and Effectiveness of IV Peramivir Versus Oseltamivir in Pediatric Subjects With Uncomplicated Influenza
Started Mar 2015
137 enrolled
Influenza
Peramivir Treatment Response in Adults Hospitalized for Influenza-associated Lower Respiratory Tract Infections
Started Feb 2011
16 enrolled
Influenza
A Study to Evaluate the Efficacy and Safety of Intravenous Peramivir in Subjects With Uncomplicated Influenza.
Started Oct 2010
0Influenza
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.