EMEND (aprepitant) by Merck & Co. is neurokinin 1 antagonists [moa]. Approved for older for the prevention of: acute, delayed nausea, vomiting associated with initial and 7 more indications. First approved in 2015.
Neurokinin 1 Antagonists
Substance P/Neurokinin-1 Receptor Antagonist
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Efficacy and Safety Study of Aprepitant Injection for Prevention of Post-operative Nausea and Vomiting
Aprepitant Injectable Emulsion in Patients With COVID-19 (GUARDS-1)
Safety of a Three-Day Fosaprepitant Regimen for the Prevention of Chemotherapy-Induced Nausea and Vomiting in Pediatric Participants (MK-0517-045)
Olanzapine With or Without Fosaprepitant Dimeglumine in Preventing Chemotherapy Induced Nausea and Vomiting in Cancer Patients Receiving Highly Emetogenic Chemotherapy
Aprepitant for the Prevention of Chemotherapy-induced Nausea and Vomiting
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Upgrade to Pro — $25/moMerck & Co. is hiring 10 roles related to this product
Patent cliff in ~2 years — expect lifecycle management and generic defense hiring