SIGNIFOR

LOE ApproachingPeptide

pasireotide

NDASUBCUTANEOUSSOLUTION
Approved
Dec 2012
Lifecycle
LOE Approaching
Competitive Pressure
25/100
Clinical Trials
20

Mechanism of Action

Somatostatin Receptor Agonists

Pharmacologic Class:

Somatostatin Analog

Clinical Trials (5)

NCT07312643Phase 1Completed

Study in Healthy Subjects to Investigate the Relative Bioavailability and Safety of Pasireotide After Single Subcutaneous Dose Administration Using a Reusable ServoPen With Cartridge as Compared to Administration Using a Syringe Drawn From an Ampule

Started Dec 2025
40 enrolled
PharmacokineticsSafety
NCT06456359Phase 2Recruiting

Pasireotide as Maintenance Treatment in Synovial Sarcoma and Desmoplastic Small Round Cell Tumor

Started Dec 2024
28 enrolled
Desmoplastic Small Round Cell TumorSynovial Sarcoma
NCT06295952Phase 2Recruiting

A Study of Pasireotide in People With Prolactinoma

Started Feb 2024
10 enrolled
Prolactin-Producing Pituitary Tumor
NCT05928390Phase 2Active Not Recruiting

Pasireotide s.c. in Patients With Post-Bariatric Hypoglycaemia

Started Jan 2024
93 enrolled
Post-Bariatric Hypoglycemia
NCT03053284Phase 2Withdrawn

Pasireotide in Hyperinsulinemic Hypoglycemia

Started Apr 2017
0
Congenital HyperinsulinismInsulinomaHyperinsulinism

Loss of Exclusivity

LOE Date
Dec 14, 2026
9 months away
Patent Expiry
Dec 14, 2026

Patent Records (1)

Patent #ExpiryTypeUse Code
7473761
Dec 14, 2026
SubstanceProduct