NDAORALTABLET
Approved
Oct 2013
Lifecycle
LOE Approaching
Competitive Pressure
25/100
Clinical Trials
3
Data completeness
8/8 — Comprehensive
DUAVEE (conjugated estrogens/bazedoxifene) by Pfizer is estrogen receptor agonists [moa]. Approved for osteoporosis. First approved in 2013.
Drug data last refreshed 18h ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
DUAVEE is an oral tablet combining conjugated estrogens with bazedoxifene, a selective estrogen receptor modulator (SERM), indicated for osteoporosis prevention and treatment in postmenopausal women. It works as an estrogen receptor agonist to maintain bone density while the SERM component provides tissue-selective effects. The combination offers a dual mechanism to address bone loss and menopausal symptoms.
$334KPart D
LOE ApproachingDeclining
10mo to LOEDUAVEE is in a mature, declining phase with minimal Part D uptake ($334K in 2023), signaling a small brand team focused on retention and transition planning.
Mechanism of Action
Estrogen Receptor Agonists
Pharmacologic Class:
Estrogen
Indications (1)
Clinical Trials (3)
The PROMISE Study: Duavee in Women With DCIS
Started Jan 2017
142 enrolled
Ductal Breast Carcinoma In SituPostmenopausal
Pilot Study of the Effect of Duavee® on Benign Breast Tissue Proliferation
Started May 2016
28 enrolled
Breast Cancer
Study Evaluating Effects of Multiple-Dose Administration of Itraconazole on the Single Dose Pharmacokinetics of Conjugated Estrogens/Bazedoxifene in Non-Obese and Obese Postmenopausal Women
Started Apr 2014
24 enrolled
Healthy
Worked on DUAVEE at Pfizer? Share your interview experience or compensation data (+7 days Pro)
Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.