NDATOPICALCLOTH
Approved
Apr 2005
Lifecycle
LOE Approaching
Competitive Pressure
15/100
Data completeness
4/8 — Partial
CHLORHEXIDINE GLUCONATE (chlorhexidine gluconate) by Becton Dickinson is clinical pharmacology periogard® (chlorhexidine gluconate oral rinse usp, 0. First approved in 2005.
Drug data last refreshed 15h ago · AI intelligence enriched 1mo ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
Chlorhexidine gluconate 0.12% oral rinse is a topical antimicrobial agent used for oral cavity disinfection and plaque reduction. It works by providing broad-spectrum antimicrobial activity against both aerobic and anaerobic oral bacteria, with approximately 30% retention in the oral cavity after rinsing. The drug is indicated for patients requiring antimicrobial oral rinse therapy, particularly in dental and perioperative settings.
LOE Approaching1.1 years to LOE
Product is approaching loss of exclusivity with moderate competitive pressure (15 competitors), signaling potential team restructuring and transition planning within the next 1-2 years.
Mechanism of Action
CLINICAL PHARMACOLOGY PerioGard® (Chlorhexidine Gluconate Oral Rinse USP, 0.12%) provides antimicrobial activity during oral rinsing. The clinical significance of chlorhexidine gluconate oral rinse's antimicrobial activities is not clear. Microbiological sampling of plaque has shown a general…
Indications
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.