NDATOPICALCLOTH
Approved
Apr 2005
Lifecycle
LOE Approaching
Competitive Pressure
15/100
Data completeness
4/8 — Partial
CHLORHEXIDINE GLUCONATE (chlorhexidine gluconate) by Becton Dickinson is clinical pharmacology periogard® (chlorhexidine gluconate oral rinse usp, 0. First approved in 2005.
Drug data last refreshed 23h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
Chlorhexidine Gluconate is a broad-spectrum antimicrobial oral rinse (0.12%) used primarily for plaque and gingivitis prevention in oral care settings. It works by reducing bacterial counts in the oral cavity by 54-97% through direct antimicrobial activity, with approximately 30% of the active ingredient retained in the oral cavity for sustained release. The drug is supplied as a topical cloth formulation and is indicated for patients requiring antimicrobial oral hygiene management.
LOE Approaching1.0 years to LOE
Product is approaching loss of exclusivity in October 2027 with limited competitive pressure (15 competitors identified), signaling potential contraction of commercial team resources.
Mechanism of Action
CLINICAL PHARMACOLOGY PerioGard® (Chlorhexidine Gluconate Oral Rinse USP, 0.12%) provides antimicrobial activity during oral rinsing. The clinical significance of chlorhexidine gluconate oral rinse's antimicrobial activities is not clear. Microbiological sampling of plaque has shown a general…
Indications
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.