Plus Therapeutics(PSTV)

Focus: Plus Therapeutics is a public-stage radiotherapy-focused biotechnology company headquartered in Austin, TX, with a highly experimental pipeline spanning oncology, infectious diseases, and other therapeutic areas.

Infectious Diseases Oncology Respiratory Ophthalmology

Profile data last refreshed 21h ago · AI intelligence enriched 2w ago

Funding Stage

PUBLIC

Open Jobs

About Plus Therapeutics

AI assessmentNot Hiring

No open roles listed right now. Follow Plus Therapeutics to get notified when they start hiring — the background below is worth knowing for when they do.

Why Work Here

Data completeness

4/9 — Basic

Company HealthSolid

Pipeline

Early-stage

50 total

LOE Risk

Protected

No near-term cliffs

Hiring

0 open

Revenue

$6M

FY2025

Pipeline & Clinical Trials

PENS

Patellofemoral Pain Syndrome

N/A

Clinical Trials (1)

NCT02441712Rehabilitation With Patterned Electrical Neuromuscular Stimulation for Patients With Patellofemoral Pain

N/A

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Data Sources

Drug label: DailyMed / FDA
Clinical trials: ClinicalTrials.gov
Patent data: FDA Orange Book
Spending data: CMS Medicare

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.

Focused radiotherapy expertise in underexplored modalities like Rhenium-186 nanoliposomes targeting difficult-to-treat CNS cancers (glioma, leptomeningeal metastasis, ependymoma)
Public company status with ticker PSTV provides equity upside potential and regulatory transparency
R&D-intensive stage (182% R&D-to-revenue ratio) means meaningful scientific contribution for researchers and technical professionals

Watch Out For

Severe financial distress: $76K cash position in FY2025 with $13M net loss, burning $5M+ annually with only $6M revenue—imminent dilution or restructuring likely
Minimal hiring momentum: only 2 open roles across entire company suggests freeze or contraction; pipeline largely Phase 1 with no clinical validation
Data integrity concerns: pipeline includes unrelated trials (aromatherapy, collagen drinks, chess therapy), suggesting poor trial management or data aggregation errors that undermine credibility

Generated by Claude from Plus Therapeutics's SEC filings, pipeline programs, hiring velocity, FDA actions, and WARN data. Inference, not editorial — verify before quoting.

Automated analysis based on publicly available data (FDA, SEC, ClinicalTrials.gov). May be incomplete or delayed. This score does not reflect insider knowledge and should not be used as the sole basis for investment or employment decisions.

Defocus-enhanced spectacles

Myopia

N/A

TRI-MOM intervention

Hiv

N/A

Juice PLUS+® OMEGA

Cognitive Change

N/A

Clinical Trials (1)

NCT05581108Enhancement of Learning and Memory Following Supplementation With Juice PLUS+® OMEGA in an Adolescent Population

N/A

yogurt intervention

Defecation Irregularity

N/A

Clinical Trials (1)

NCT06862310Effects of Fermented Dairy Products on Defecation Changes Through Gut Microbiota

N/A

Kagocel

Influenza

N/A

Clinical Trials (1)

NCT02983019Treatment of Influenza in Routine Clinical Practice

N/A

no interventional study

COVID-19

N/A

Clinical Trials (1)

NCT05524792Incidence of Diabetes After a COVID-19 Infection

N/A

cellulose

Crohn Disease

N/A

Clinical Trials (1)

NCT04370535PMA-Zeolite-Clinoptilolite Effects in Crohn Disease

N/A

Kagocel

Influenza

N/A

Clinical Trials (1)

NCT04651491Treatment of Influenza and ARVI in Children by Kagocel ®

N/A

Kagocel+Valacyclovir

Herpes

N/A

Clinical Trials (1)

NCT04664127Study of the Efficacy and Safety of Combined Treatment of Patients With Severe Herpes Simplex (HSV) Infection by Valacyclovir and Interferon Inducer Kagocel

N/A

Coordination through the online platform "JamesAKTIV"

Parkinson Disease

N/A

Clinical Trials (1)

NCT05251298"Parkinson AKTIV - Non-pharmacological Treatments in an Innovative Parkinson's Network"

N/A

Collateral Circulation in Acute Ischemic Stroke With Large Vessel Occlusion

Stroke, Ischemic

N/A

Clinical Trials (1)

NCT04882657Collateral Circulation in Acute Ischemic Stroke With Large Vessel Occlusion

N/A

Vitamin D supplement

Mental Wellbeing

N/A

Clinical Trials (1)

NCT05724316Effects of Vitamin D on the Behaviours, Mental, and Physical Health of Prisoners

N/A

Self-tonometry by means of ICareHOME

Glaucoma

N/A

Clinical Trials (1)

NCT04698876Self Tonometry and Transfer of Glaucoma Patients' Data for Improving the Supply Situation

N/A

Yes We Can Children's Asthma Program

Childhood Asthma

N/A

Clinical Trials (1)

NCT03514485West Philadelphia Controls Asthma

N/A

Collagen Drinks

Skin Aging

N/A

Clinical Trials (1)

NCT06900660Evaluation of the Skin-Beautifying Effects of Collagen Drinks

N/A

Intermittent Theta Burst Stimulation to Right DLPFC

ADHD - Attention Deficit Disorder With Hyperactivity

N/A

Clinical Trials (1)

NCT07182344Brain Stimulation and Attention Control in Children With ADHD

N/A

EpiCor and Vitamin C

Signs and Symptoms, Respiratory

N/A

Clinical Trials (1)

NCT04093206Compare Effects of EpiCor and Vitamin C to Vitamin C Alone on the Common Cold or Influenza in Healthy Children

N/A

Collagen for injections 7%

Skin Aging

N/A

Clinical Trials (1)

NCT03677258Effectiveness and Safety of Collagen Complex COLLOST in Anti-age Therapy

N/A

MolecuLight

Non-Healing Ulcer of Skin

N/A

Clinical Trials (1)

NCT06068972Retrospective Database Review at LTC and SNFs

N/A

Abuja Heart Study: Prospective Epidemiological Investigation of Cardiovascular Diseases

Cardiovascular Diseases

N/A

Clinical Trials (1)

NCT00629954Abuja Heart Study: Prospective Epidemiological Investigation of Cardiovascular Diseases

N/A

Kagocel

Acute Upper Respiratory Tract Infection

N/A

Clinical Trials (1)

NCT04611061Kagocel® for the Prevention of ARVI and Influenza in Adults Health Care Workers

N/A

CONTINUUM+ CONNECT remote monitoring

Prostatic Neoplasms

N/A

Clinical Trials (1)

NCT06379880Impact on Quality of Life and Health of the CONTINUUM+ CONNECT Remote Monitoring Solution

N/A

Continuous Theta Burst Stimulation to Bilateral DLPFC

Autism Spectrum Disorder (ASD)

N/A

Clinical Trials (1)

NCT07182331Brain Stimulation and Sensory Integration in Children With ASD

N/A

Experimental arm

Dementia

N/A

Clinical Trials (1)

NCT07251088Dyadic, App-supported Collaborative Care Intervention Trial for Family Caregivers of People Living With Dementia

N/A

400mg /day during 6 months

Androgenic Alopecia

N/A

Clinical Trials (1)

NCT01852487Effect of Pumpkin Seed Oil on Hair Growth in Men With Androgenetic Alopecia

N/A

Gundo So

HIV Seropositivity

N/A

Clinical Trials (1)

NCT03795415ANRS12373 GUNDO SO - Evaluation of an Empowerment Program for WLHIV in Mali

N/A

Novel Microbicidal Liquid Polymer

Infection

N/A

Clinical Trials (1)

NCT03756506The Use of a Novel Microbicidal Liquid Polymer for the Reduction of Pin Track Infection

N/A

Intradialytic exercise intervention

Chronic Kidney Diseases

N/A

Local community-based HIV care

HIV Infections

N/A

Clinical Trials (1)

NCT04482010ANRS 12392 Sanu Gundo

N/A

Wavelight Plus Alcon system

Myopia

N/A

Oral swab DNA analyzed for myopia-related gene variants

Myopia

N/A

dual expert guidance structure

Rare Diseases

N/A

Aromatherapy blend

Post-operative Nausea

N/A

Clinical Trials (1)

NCT02189980Aromatherapy Using a Nasal Clip After Surgery

N/A

Exposed to a SARS-CoV-2 infection

Virus Diseases

N/A

Clinical Trials (1)

NCT05606198Post-COVID-19 Monitoring in Routine Health Insurance Data With Focus on Autoimmune Diseases (POINTED-AD)

N/A

Stability Plus - Outcomes From Extended Continuum of Care

Arthroplasty

N/A

Clinical Trials (1)

NCT00756483Stability Plus - Outcomes From Extended Continuum of Care

N/A

Firefighter Cardiorespiratory Fitness (CRF) Pilot Study

Cardiorespiratory Fitness

N/A

EHSSA- An Efficient and Holistic/Heuristic Semi-structured Suicide Assessment Tool

Suicide Risk

N/A

Clinical Trials (1)

NCT04888533Efficient, Holistic, Heuristic and Semi-structured Suicide Assessment Tool (EHSSA) - Very Accurate Prediction of Risk.

N/A

Exposed to a SARS-CoV-2 infection

Virus Diseases

N/A

Clinical Trials (1)

NCT05074953Post-COVID-19 Monitoring in Routine Health Insurance Data

N/A

Kagocel

Acute Upper Respiratory Tract Infection

N/A

Clinical Trials (1)

NCT04626622Kagocel® for the Prevention of ARVI and Influenza in Young People

N/A

Chest compressions

Resuscitation

N/A

Clinical Trials (1)

NCT06070077CPR Quality in Via Ferrata Rescues

N/A

PBTZ169 640 mg OD

Healthy Subjects

PHASE_1

Clinical Trials (1)

NCT04150224Safety, Tolerability, Pharmacokinetics and Food Effects Study of PBTZ169

Phase 1

Retreatment Rhenium Liposome

Glioma

PHASE_1

Clinical Trials (1)

NCT05460507Safety & Efficacy/Tolerability of Rhenium-186 NanoLiposomes (186RNL) for Patients Who Received a Prior 186RNL Treatment

Phase 1

PBTZ169 - 40 mg

Tuberculosis

PHASE_1

Clinical Trials (1)

NCT03036163Phase 1 Study of PBTZ169

Phase 1

186RNL

Leptomeningeal Metastasis

PHASE_1

Clinical Trials (1)

NCT07098806Multiple Dose Intraventricular Administration of Rhenium-186 NanoLiposome for Leptomeningeal Metastases

Phase 1

186RNL

Leptomeningeal Metastasis

PHASE_1

Clinical Trials (1)

NCT05034497Intraventricular Administration of Rhenium-186 NanoLiposome for Leptomeningeal Metastases

Phase 1

Rhenium-186 Nanoliposome

Ependymoma

PHASE_1

Clinical Trials (1)

NCT07061626Determine Maximum Tolerated Dose, Safety, and Tolerability of Rhenium (186Re) in Pediatric Recurrent, Refractory or Progressive Ependymoma and High-Grade Glioma

Phase 1

Rhenium Liposome Treatment

Glioma

PHASE_1_2

Clinical Trials (1)

NCT01906385Maximum Tolerated Dose, Safety, and Efficacy of Rhenium Nanoliposomes in Recurrent Glioma (ReSPECT)

Phase 1/2

Bio-K+ CL1285

MRSA Colonization

PHASE_2

Open Jobs (0)

No open positions listed yet. Check their careers page directly.

Interview Prep Quick Facts

Portfolio: 41 clinical trials

Top TAs: Oncology

Publications: 3 in PubMed

SEC Filings: 2 available

Therapeutic Area Focus

Oncology

5 pipeline

Marketed

Pipeline

Financials (FY2025)

Revenue

$6M19%

R&D Spend

$11M(182%)9%

Net Income

-$13M

Research Publications(3)

Recent peer-reviewed publications with author affiliations at this company

Multimodal evaluation of cerebrospinal fluid from breast cancer leptomeningeal metastases using circulating tumor cell detection, single-cell sequencing, and proteomics.

Journal of translational medicine

2025

PMID:40640833

Convection enhanced delivery of Rhenium ((186)Re) Obisbemeda ((186)RNL) in recurrent glioma: a multicenter, single arm, phase 1 clinical trial.