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Skin Aging

4
Pipeline Programs
12
Companies
11
Clinical Trials
1 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
2
2
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

11 companies ranked by most advanced pipeline stage

Bausch Health
Bausch HealthQUEBEC, Quebec, Canada
1 program
1
Poly-L-Lactic AcidPhase 41 trial
Active Trials
NCT00447551Completed76Est. Apr 2008
AbbVie
AbbVieNORTH CHICAGO, IL
1 program
1
botulinum toxin Type APhase 41 trial
Active Trials
NCT00856414Completed45Est. Apr 2009
Biolab Pharma
Biolab PharmaBrazil - São Paulo
1 program
1
Botulinum Toxin APhase 31 trial
Active Trials
NCT00986570Completed121Est. Nov 2010
Galderma
GaldermaTX - Dallas
1 program
1
MoisturizerPhase 31 trial
Active Trials
NCT00629317Completed49Est. Mar 2009
Plus Therapeutics
2 programs
Collagen DrinksN/A1 trial
Collagen for injections 7%N/A1 trial
Active Trials
NCT06900660Active Not RecruitingEst. Aug 2025
NCT03677258CompletedEst. Jul 2018
Plasma Surgical
Plasma SurgicalFrance - Villebon-Sur-Yvette
1 program
Exposure to plasma energyN/A1 trial
Active Trials
NCT00761878Completed35Est. Jun 2009
Kimia Therapeutics
Kimia TherapeuticsCA - Berkeley
1 program
Fractional CO₂ LaserN/A1 trial
Active Trials
NCT05508191Completed30Est. Dec 2022
Bioiberica
BioibericaSpain - Barcelona
1 program
HA matrix ingredientN/A1 trial
Active Trials
NCT05813054Completed60Est. Sep 2023
IBSA Institut Biochimique
IBSA Institut BiochimiqueSwitzerland - Lugano-Pazzallo
1 program
Profhilo StructuraN/A1 trial
Active Trials
NCT06719154Recruiting164Est. Dec 2025
GSK
GSKLONDON, United Kingdom
1 program
Test productN/A1 trial
Active Trials
NCT03180645Completed72Est. Apr 2017
ViiV Healthcare
ViiV HealthcareNC - Durham
1 program
Test productN/A

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
AbbViebotulinum toxin Type A
Bausch HealthPoly-L-Lactic Acid
Biolab PharmaBotulinum Toxin A
GaldermaMoisturizer
Plus TherapeuticsCollagen Drinks
IBSA Institut BiochimiqueProfhilo Structura
BioibericaHA matrix ingredient
Kimia TherapeuticsFractional CO₂ Laser
Plus TherapeuticsCollagen for injections 7%
GSKTest product
Plasma SurgicalExposure to plasma energy

Clinical Trials (11)

Total enrollment: 652 patients across 11 trials

NCT00856414AbbViebotulinum toxin Type A

Patient Satisfaction With Treatment of BOTOX® Cosmetic for the Temporary Correction of Moderate to Severe Glabellar Lines

Start: Mar 2009Est. completion: Apr 200945 patients
Phase 4Completed
NCT00447551Bausch HealthPoly-L-Lactic Acid

Canadian Aesthetic Experience With Sculptra Therapy

Start: Jan 2007Est. completion: Apr 200876 patients
Phase 4Completed
NCT00986570Biolab PharmaBotulinum Toxin A

Clinical Trial to Assess Efficacy, Safety and Tolerability of Botulinum Toxin A (Xeomin®) in Treatment of Expression Wrinkles in the Upper Third of the Face

Start: Sep 2009Est. completion: Nov 2010121 patients
Phase 3Completed
NCT00629317GaldermaMoisturizer

Trial of Methyl Aminolevulinate Plus Aktilite in Facial Photodamage

Start: Feb 2008Est. completion: Mar 200949 patients
Phase 3Completed
NCT06900660Plus TherapeuticsCollagen Drinks

Evaluation of the Skin-Beautifying Effects of Collagen Drinks

Start: Jan 2025Est. completion: Aug 2025
N/AActive Not Recruiting
NCT06719154IBSA Institut BiochimiqueProfhilo Structura

Evaluation of the Safety and Efficacy of Profhilo® Structura

Start: Sep 2024Est. completion: Dec 2025164 patients
N/ARecruiting
NCT05813054BioibericaHA matrix ingredient

Clinical Study to Evaluate the Anti-aging Efficacy of Dermial®

Start: Oct 2022Est. completion: Sep 202360 patients
N/ACompleted
NCT05508191Kimia TherapeuticsFractional CO₂ Laser

Microneedle Versus Fractional CO₂ Laser for Skin Aging Treatment With Stem Cell Secretome in Indonesian Adult Women

Start: Aug 2022Est. completion: Dec 202230 patients
N/ACompleted
NCT03677258Plus TherapeuticsCollagen for injections 7%

Effectiveness and Safety of Collagen Complex COLLOST in Anti-age Therapy

Start: Oct 2017Est. completion: Jul 2018
N/ACompleted
NCT03180645GSKTest product

Proof of Concept Anti-ageing Clinical Study in Healthy Subjects

Start: Mar 2017Est. completion: Apr 201772 patients
N/ACompleted
NCT00761878Plasma SurgicalExposure to plasma energy

Evaluation of the PlasmaJet Neutral Argon Plasma System to Treat Skin Ageing

Start: Dec 2007Est. completion: Jun 200935 patients
N/ACompleted

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

2 late-stage (Phase 3) programs, potential near-term approvals
1 actively recruiting trials targeting 652 patients
12 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.