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Ependymoma

1
Pipeline Programs
3
Companies
2
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
1
0
0
0
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Monoclonal Antibody
150%
Small Molecule
150%
+ 1 programs with unclassified modality

Competitive Landscape

3 companies ranked by most advanced pipeline stage

Astellas
AstellasChina - Shenyang
1 program
1
ErlotinibPhase 2Small Molecule1 trial
Active Trials
NCT01247922Terminated4Est. Sep 2012
Plus Therapeutics
1 program
Rhenium-186 NanoliposomePHASE_11 trial
Active Trials
NCT07061626Not Yet Recruiting56Est. Mar 2027
Nektar Therapeutics
Nektar TherapeuticsSAN FRANCISCO, CA
1 program
NivolumabPHASE_1_2Monoclonal Antibody

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
AstellasErlotinib
Plus TherapeuticsRhenium-186 Nanoliposome

Clinical Trials (2)

Total enrollment: 60 patients across 2 trials

Single-agent Erlotinib in Patients Previously Treated With Oral Etoposide in Protocol OSI-774-205

Start: May 2011Est. completion: Sep 20124 patients
Phase 2Terminated
NCT07061626Plus TherapeuticsRhenium-186 Nanoliposome

Determine Maximum Tolerated Dose, Safety, and Tolerability of Rhenium (186Re) in Pediatric Recurrent, Refractory or Progressive Ependymoma and High-Grade Glioma

Start: Sep 2025Est. completion: Mar 202756 patients
Phase 1Not Yet Recruiting

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

3 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.