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Virus Diseases

14
Pipeline Programs
6
Companies
16
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
3
0
6
0
1
4
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Small Molecule
250%
Vaccine
250%
+ 21 programs with unclassified modality

Competitive Landscape

6 companies ranked by most advanced pipeline stage

ViiV Healthcare
ViiV HealthcareNC - Durham
11 programs
2
4
1
4
Blood drawPhase 41 trial
Encepur AdultsPhase 41 trial
RabipurPhase 41 trial
Valaciclovir HydrochloridePhase 41 trial
RabipurPhase 31 trial
+6 more programs
Active Trials
NCT04758962Completed40Est. Apr 2022
NCT04062669Completed160Est. Jul 2022
NCT02927431Terminated10Est. May 2017
+8 more trials
Syneos Health
Syneos HealthNC - Morrisville
3 programs
1
2
20 micrograms dose H5 VLPPhase 21 trial
Low dose of H5 VLP vaccine + AlhydrogelPhase 2Vaccine1 trial
Low dose of H7 VLP vaccine + AlhydrogelPhase 1Vaccine1 trial
Active Trials
NCT02022163Completed100Est. Dec 2014
NCT01244867Completed255Est. Sep 2011
NCT01991561Completed390Est. Nov 2014
GSK
GSKLONDON, United Kingdom
7 programs
1 µg CoV2 SAMPHASE_1
GlaxoSmithKlinePHASE_2
RabipurPHASE_3
Blood drawPHASE_4
Encepur AdultsPHASE_4
+2 more programs
Plus Therapeutics
2 programs
Exposed to a SARS-CoV-2 infectionN/A1 trial
Exposed to a SARS-CoV-2 infectionN/A1 trial
Active Trials
NCT05074953CompletedEst. Dec 2023
NCT05606198CompletedEst. Jun 2023
Sharp Therapeutics
Sharp TherapeuticsPA - Pittsburgh
1 program
Switch NRTIs as a Backbone to RaltegravirN/ASmall Molecule
MSD
MSDIreland - Ballydine
1 program
Switch NRTIs as a Backbone to RaltegravirN/ASmall Molecule

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
ViiV HealthcareRabipur
ViiV HealthcareEncepur Adults
ViiV HealthcareBlood draw
ViiV HealthcareValaciclovir Hydrochloride
ViiV HealthcareRabipur
ViiV HealthcareDanirixin 15 mg FBE
ViiV HealthcareGlaxoSmithKline
ViiV HealthcareGlaxoSmithKline
ViiV HealthcareGSK1325756
Syneos HealthLow dose of H5 VLP vaccine + Alhydrogel
Syneos Health20 micrograms dose H5 VLP
ViiV Healthcare1 µg CoV2 SAM
ViiV HealthcareLow dose formulation of RG SAM
Syneos HealthLow dose of H7 VLP vaccine + Alhydrogel
Plus TherapeuticsExposed to a SARS-CoV-2 infection

Showing 15 of 16 trials with date data

Clinical Trials (16)

Total enrollment: 5,445 patients across 16 trials

A Study to Evaluate the One Year Long-term Persistence of Immune Responses Following Two Different Rabies Vaccine Post-exposure Regimens in Chinese Children

Start: Feb 2018Est. completion: May 20190
Phase 4Withdrawn

The Aim of This Study is to Investigate the Persistence of Antibody Response in Adults up to 15 Years After One Booster Dose of GlaxoSmithKline (GSK) Biologicals' Encepur Adults Vaccine

Start: Oct 2017Est. completion: Oct 2021194 patients
Phase 4Completed

A Study to Evaluate Persistence of Immune Responses After Post-exposure Prophylaxis of Rabipur® (Purified Chicken-embryo Cell Rabies Vaccine) in Chinese Children

Start: Dec 2016Est. completion: Mar 2017150 patients
Phase 4Completed
NCT00343278ViiV HealthcareValaciclovir Hydrochloride

Pharmacokinetic Study Of Valaciclovir Hydrochloride Tablets

Start: Jul 2005Est. completion: Aug 200518 patients
Phase 4Completed

A Phase 3 Clinical Trial to Evaluate Long-term Immunogenicity and Boostability of Purified Chick-Embryo Cell Rabies Vaccine in Adults Following Primary Series of Pre/Exposure Prophylaxis.

Start: Oct 2015Est. completion: Dec 2022459 patients
Phase 3Completed
NCT02927431ViiV HealthcareDanirixin 15 mg FBE

Study to Evaluate the Efficacy and Safety of Danirixin Co-administered With Oseltamivir in the Treatment of Adults Hospitalized With Influenza

Start: Jan 2017Est. completion: May 201710 patients
Phase 2Terminated

A Study to Evaluate the Safety and Immunogenicity of a Candidate Ebola Vaccine in Children

Start: Nov 2015Est. completion: May 2017600 patients
Phase 2Completed

A Study to Evaluate the Safety and Immunogenicity of a Candidate Ebola Vaccine in Adults

Start: Jul 2015Est. completion: Dec 20163,024 patients
Phase 2Completed

Safety, Tolerability and Clinical Effect of Danirixin in Adults With Influenza

Start: Jun 2015Est. completion: Apr 201645 patients
Phase 2Completed
NCT01991561Syneos HealthLow dose of H5 VLP vaccine + Alhydrogel

Immunogenicity, Safety, Tolerability of a Plant-made H5 Virus-like-particle (VLP) Influenza Vaccine.

Start: Jun 2013Est. completion: Nov 2014390 patients
Phase 2Completed
NCT01244867Syneos Health20 micrograms dose H5 VLP

Immunogenicity, Safety, Tolerability of a Plant-Made H5 VLP Influenza Vaccine

Start: Nov 2010Est. completion: Sep 2011255 patients
Phase 2Completed

A Study of the Safety of and Immune Response to Varying Doses of a Vaccine Against COVID-19 in Healthy Adults

Start: Feb 2021Est. completion: Apr 202240 patients
Phase 1Completed
NCT04062669ViiV HealthcareLow dose formulation of RG SAM

A Study to Evaluate the Safety and Immunogenicity of GlaxoSmithKline (GSK) Biologicals' Experimental Rabies Vaccine in Healthy Adults

Start: Aug 2019Est. completion: Jul 2022160 patients
Phase 1Completed
NCT02022163Syneos HealthLow dose of H7 VLP vaccine + Alhydrogel

Safety, Tolerability and Immunogenicity of a Plant-made H7 Virus-like Particle (VLP) Influenza Vaccine in Adults.

Start: Dec 2013Est. completion: Dec 2014100 patients
Phase 1Completed
NCT05606198Plus TherapeuticsExposed to a SARS-CoV-2 infection

Post-COVID-19 Monitoring in Routine Health Insurance Data With Focus on Autoimmune Diseases (POINTED-AD)

Start: May 2022Est. completion: Jun 2023
N/ACompleted
NCT05074953Plus TherapeuticsExposed to a SARS-CoV-2 infection

Post-COVID-19 Monitoring in Routine Health Insurance Data

Start: Aug 2021Est. completion: Dec 2023
N/ACompleted

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

1 late-stage (Phase 3) programs, potential near-term approvals
6 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.