Stroke, Ischemic

Neurology
2
Pipeline Programs
8
Companies
7
Clinical Trials
1 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
1
0
1
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

6 companies ranked by most advanced pipeline stage

Boehringer Ingelheim
Boehringer IngelheimINGELHEIM, Germany
1 program
1
TenecteplasePhase 31 trial
Active Trials
NCT05199194Recruiting398Est. Jul 2027
Revalesio
RevalesioWA - Tacoma
1 program
1
RNS60Phase 21 trial
Active Trials
NCT04693715CompletedEst. Nov 2023
Penumbra
PenumbraALAMEDA, CA
2 programs
Penumbra SystemN/A1 trial
Penumbra SystemN/A1 trial
Active Trials
NCT04157270Terminated23Est. May 2021
NCT03464565Completed650Est. Jan 2020
Verona Pharma
Verona PharmaUK - London
1 program
Anodal transcranial direct current stimulationN/A1 trial
Active Trials
NCT04166968UnknownEst. Dec 2020
Plus Therapeutics
1 program
Collateral Circulation in Acute Ischemic Stroke With Large Vessel OcclusionN/A1 trial
Active Trials
NCT04882657UnknownEst. Dec 2022
Viz.ai
Viz.aiCA - San Francisco
1 program
Viz LVON/A1 trial
Active Trials
NCT04608617Completed600Est. Apr 2023

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
Boehringer IngelheimTenecteplase
RevalesioRNS60
Plus TherapeuticsCollateral Circulation in Acute Ischemic Stroke With Large Vessel Occlusion
Viz.aiViz LVO
PenumbraPenumbra System
Verona PharmaAnodal transcranial direct current stimulation
PenumbraPenumbra System

Clinical Trials (7)

Total enrollment: 1,671 patients across 7 trials

NCT05199194Boehringer IngelheimTenecteplase

Randomization to Endovascular Treatment Alone or Preceded by Systemic Thrombolysis With Tenecteplase in Ischemic Stroke

Start: May 2022Est. completion: Jul 2027398 patients
Phase 3Recruiting
NCT04693715RevalesioRNS60

Safety of RNS60 in Large Vessel Occlusion Stroke Patients Undergoing Endovascular Thrombectomy

Start: Jul 2021Est. completion: Nov 2023
Phase 2Completed
NCT04882657Plus TherapeuticsCollateral Circulation in Acute Ischemic Stroke With Large Vessel Occlusion

Collateral Circulation in Acute Ischemic Stroke With Large Vessel Occlusion

Start: Jun 2021Est. completion: Dec 2022
N/AUnknown
NCT04608617Viz.aiViz LVO

SYNCHRONISE: LVO Triage Timing and Outcome Study

Start: Mar 2021Est. completion: Apr 2023600 patients
N/ACompleted
NCT04157270PenumbraPenumbra System

LOTUS: Global Acute Stroke Study Utilizing Penumbra System

Start: Jan 2020Est. completion: May 202123 patients
N/ATerminated
NCT04166968Verona PharmaAnodal transcranial direct current stimulation

Multicenter Study on the Efficacy of Transcranial Direct Current Stimulation (tDCS) in Post-stroke Motor Recovery

Start: Oct 2019Est. completion: Dec 2020
N/AUnknown
NCT03464565PenumbraPenumbra System

COMPLETE: International Acute Ischemic Stroke Registry With the Penumbra System Aspiration Including the 3D Revascularization Device

Start: Jul 2018Est. completion: Jan 2020650 patients
N/ACompleted

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Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

1 late-stage (Phase 3) programs — potential near-term approvals
1 actively recruiting trials targeting 1,671 patients
8 companies competing in this space

Related Indications

Multiple Sclerosis(274)Schizophrenia(255)Epilepsy(242)Parkinson Disease(171)Alzheimer's Disease(165)Parkinson's Disease(160)Alzheimer Disease(117)Stroke(102)Relapsing-Remitting Multiple Sclerosis(83)Depression(82)