PTC Therapeutics

PTC Therapeutics(PTCT)

WARREN, NJ
Biotechnology4 H-1B visas (FY2023)

Focus: Small Molecules, Gene Therapy

PTC Therapeutics is a life sciences company focused on Small Molecules, Gene Therapy.

Gene Therapy
Funding Stage
PUBLIC
Open Jobs
19

Products & Portfolio (3)

Pipeline & Clinical Trials

A Study to Collect Blood Samples From Patients With Spinal Muscular Atrophy for Biomarker Analysis
Muscular Atrophy, Spinal
N/A
Clinical Trials (1)
NCT01910168A Study to Collect Blood Samples From Patients With Spinal Muscular Atrophy for Biomarker Analysis
N/A
N/A
Clinical Trials (1)
NCT07159139Vatiquinone Expanded Access Protocol
N/A
Clinical Trials (1)
NCT01370447EPI-743 for Mitochondrial Respiratory Chain Diseases
N/A
Clinical Trials (1)
NCT02592941Deflazacort Expanded Access Program for Children, Adolescents and Adults With Duchenne Muscular Dystrophy
N/A
Registry of Translarna (Ataluren) in Nonsense Mutation Duchenne Muscular Dystrophy (nmDMD)
Muscular Dystrophy, Duchenne
N/A
Clinical Trials (1)
NCT02369731Registry of Translarna (Ataluren) in Nonsense Mutation Duchenne Muscular Dystrophy (nmDMD)
N/A
Phase 1
Clinical Trials (1)
NCT02295748An Open-Label, Long-Term Extension Study to Evaluate the Safety and Tolerability Deflazacort
Phase 1
Phase 1
Clinical Trials (1)
NCT03206645Unesbulin in Women With Ovarian Cancer Receiving Neoadjuvant Chemotherapy
Phase 1
Phase 1
Clinical Trials (1)
NCT02286609A Single Dose Evaluation of the Effects of Moderate Hepatic Impairment on Deflazacort Pharmacokinetics
Phase 1
Deflazacort and rifampin
Healthy Volunteers
Phase 1
Clinical Trials (1)
NCT02286635Evaluate Effects of Multiple Doses of Rifampin and Clarithromycin on the Single Dose Pharmacokinetics of Deflazacort
Phase 1
Phase 1
Clinical Trials (1)
NCT01158300PTC299 in Treating Young Patients With Refractory or Recurrent Primary Central Nervous System Tumors
Phase 1
Phase 1
Clinical Trials (1)
NCT02251600A Pharmacokinetic Study of Oral Deflazacort in Children and Adolescent Subjects With Duchenne Muscular Dystrophy
Phase 1
Clinical Trials (1)
NCT03761069Study of PTC299 (Emvododstat) in Relapsed/Refractory Acute Leukemias
Phase 1
PTC596
Cancer
Phase 1
Clinical Trials (1)
NCT02404480PTC596 in Patients With Advanced Solid Tumors
Phase 1
Deflazacort
Renal Impairment
Phase 1
Clinical Trials (1)
NCT02286622A Single Dose Evaluation of the Effects of Renal Impairment on Deflazacort Pharmacokinetics
Phase 1
Phase 1
Clinical Trials (1)
NCT03761095A Study of Unesbulin (PTC596) in Combination With Dacarbazine in Participants With Advanced Leiomyosarcoma (LMS)
Phase 1
Phase 1
Clinical Trials (1)
NCT02485431Food Effect and Bioavailability of Deflazacort Formulations in Healthy Volunteers
Phase 1
Phase 1
Clinical Trials (1)
NCT03605550A Phase 1b Study of PTC596 in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma and High Grade Glioma
Phase 1
Clinical Trials (1)
NCT00508586PTC299 and Hormonal Agent for Treatment of Metastatic Breast Cancer
Phase 1
Phase 1
Clinical Trials (1)
NCT00704821PTC299 for Treatment of Advanced Cancer
Phase 1
Ataluren
Healthy
Phase 1
Clinical Trials (1)
NCT02409004Effects of Rifampin on the Pharmacokinetics of Ataluren
Phase 1
VEGF inhibitor PTC299
Kaposi's Sarcoma
Phase 1/2
Clinical Trials (1)
NCT00686842PTC299 in Treating Patients With HIV-Related Kaposi Sarcoma
Phase 1/2
Clinical Trials (1)
NCT01395641A Phase I/II Clinical Trial for Treatment of Aromatic L-amino Acid Decarboxylase (AADC) Deficiency Using AAV2-hAADC
Phase 1/2
Ataluren + Pembrolizumab
Colorectal Cancer
Phase 1/2
Clinical Trials (1)
NCT04014530Pembrolizumab With Ataluren in Patients With Metastatic pMMR and dMMR Colorectal Carcinoma or Metastatic dMMR Endometrial Carcinoma: the ATAPEMBRO Study
Phase 1/2
Phase 1/2
Clinical Trials (1)
NCT03519711A Study of PTC923 (CNSA-001) in Primary Tetrahydrobiopterin (BH4) Deficient Participants With Hyperphenylalaninemia
Phase 1/2
Eladocagene Exuparvovec
AADC Deficiency
Phase 2
Clinical Trials (1)
NCT04903288A Study of SmartFlow Magnetic Resonance (MR) Compatible Ventricular Cannula for Administering Eladocagene Exuparvovec to Pediatric Participants
Phase 2
Clinical Trials (1)
NCT02819557Study of Ataluren in ≥2 to <5 Year-Old Male Participants With Duchenne Muscular Dystrophy
Phase 2
Phase 2
Clinical Trials (1)
NCT03712124A Study of CNSA-001 in Women With Diabetic Gastroparesis
Phase 2
Clinical Trials (1)
NCT04336826A Study to Evaluate the Safety and Pharmacokinetics of Ataluren in Participants From ≥6 Months to <2 Years of Age With Nonsense Mutation Duchenne Muscular Dystrophy (nmDMD)
Phase 2
Clinical Trials (1)
NCT05349721Study to Assess the Effects of PTC857 Treatment in Participants With Amyotrophic Lateral Sclerosis ALS
Phase 2
Ataluren
Hemophilia A
Phase 2
Clinical Trials (1)
NCT00947193Study of Ataluren (PTC124) in Hemophilia A and B
Phase 2
Clinical Trials (1)
NCT00592553Phase 2B Study of PTC124 (Ataluren) in Duchenne/Becker Muscular Dystrophy (DMD/BMD)
Phase 2
Clinical Trials (1)
NCT00264888Safety and Efficacy Study of PTC124 in Duchenne Muscular Dystrophy
Phase 2
Clinical Trials (1)
NCT00847379Phase 2B Extension Study of Ataluren (PTC124) in Duchenne/Becker Muscular Dystrophy (DMD/BMD)
Phase 2
Clinical Trials (1)
NCT02460679Safety and Biomarker Study of EPI-589 in Participants With Amyotrophic Lateral Sclerosis (ALS)
Phase 2
Ataluren
Aniridia
Phase 2
Clinical Trials (1)
NCT04117880A Phase 2 Open Label Extension Study in Participants With Nonsense Mutation Aniridia
Phase 2
Phase 2
Clinical Trials (1)
NCT00237380Safety and Efficacy of Ataluren (PTC124) for Cystic Fibrosis
Phase 2
Phase 2
Clinical Trials (1)
NCT00911248PTC299 for Treatment of Neurofibromatosis Type 2
Phase 2
Ataluren
Aniridia
Phase 2
Clinical Trials (1)
NCT02647359Study of Ataluren in Participants With Nonsense Mutation Aniridia
Phase 2
Clinical Trials (1)
NCT01141075Ataluren for Nonsense Mutation Methylmalonic Acidemia
Phase 2
Phase 2
Clinical Trials (1)
NCT01728064Safety and Efficacy of EPI-743 in Patients With Friedreich's Ataxia
Phase 2
Phase 2
Clinical Trials (1)
NCT05358717A Study to Evaluate the Safety and Efficacy of PTC518 in Participants With Huntington's Disease (HD)
Phase 2
Phase 2
Clinical Trials (1)
NCT05485987A Study of Vatiquinone for the Treatment of Participants With Friedreich Ataxia
Phase 2
Phase 2
Clinical Trials (1)
NCT00234663PTC124 for Cystic Fibrosis
Phase 2
Clinical Trials (1)
NCT03796637A Study to Assess Dystrophin Levels in Participants With Nonsense Mutation Duchenne Muscular Dystrophy (nmDMD) Who Have Been Treated With Ataluren
Phase 2
Clinical Trials (1)
NCT02926066A Clinical Trial for Treatment of Aromatic L-amino Acid Decarboxylase (AADC) Deficiency Using AAV2-hAADC - An Expansion
Phase 2
Phase 2
Clinical Trials (1)
NCT02352896Long-Term Safety and Efficacy Evaluation of EPI-743 in Children With Leigh Syndrome
Phase 2
Phase 2
Clinical Trials (1)
NCT00351078PTC124 for the Treatment of Cystic Fibrosis
Phase 2
Phase 2
Clinical Trials (1)
NCT01721733Safety and Efficacy Study of EPI-743 in Children With Leigh Syndrome
Phase 2
ataluren
Epilepsy
Phase 2
Clinical Trials (1)
NCT02758626Ataluren for Nonsense Mutation in CDKL5 and Dravet Syndrome
Phase 2
Clinical Trials (1)
NCT03648827A Study to Assess Dystrophin Levels in Participants With Nonsense Mutation Duchenne Muscular Dystrophy (nmDMD)
Phase 2

Open Jobs (19)

Senior Manager, Clinical Pharmacology

USA - New Jersey - Warren
23h ago
$128K - $161K/yr

Scientific Engagement Specialist

Remote
Yesterday
$85K - $107K/yr

Contract, Analytical Development

USA - New Jersey - Bridgewater
Yesterday
$60 - $85/hr

Contract, Clinical Trial Associate

USA - New Jersey - Warren
5d ago
$35 - $47/hr

Senior Director, Biostatistics

USA - New Jersey - Warren
5d ago
$239K - $281K/yr

Associate Vice President, Global Medical Affairs Therapy Area Lead - PKU

USA - New Jersey - Warren
1w ago
$331K - $390K/yr

Manager, Corporate Paralegal R&D/Tech Ops (Hybrid)

USA - New Jersey - Warren
Research & Development
1w ago
$120K - $125K/yr

Assoc. Mgr., Corporate Paralegal R&D/Tech Ops (Hybrid)

USA - New Jersey - Warren
Research & Development
1w ago
$100K - $115K/yr

Associate Director, Biostatistics

USA - New Jersey - Warren
Data Science & AI
2w ago
$164K - $206K/yr

Scientist I, Chemoproteomics

USA - California - Mountain View
Research & Development
2w ago
$119K - $142K/yr

Research Associate II, Mass Spectrometry

USA - California - Mountain View
Research & Development
2w ago
$83K - $98K/yr

Sr. Medical Science Liaison

Remote
Medical Affairs
2w ago

Associate Director, Clinical Data Management

USA - New Jersey - Warren
Clinical Operations
3w ago
$164K - $206K/yr

Senior Vice President, Clinical Development (MD)

USA - New Jersey - Warren
Clinical Operations
3w ago
$425K - $485K/yr

Contract, Drug Metabolism and Pharmacokinetics (DMPK)

USA - New Jersey - Bridgewater
Commercial
1mo ago
$45 - $70/hr

Senior Specialist, Artworks

Remote
Commercial
1mo ago

Case Manager, Patient Services (Rare Disease)

Remote
Commercial
2mo ago
$75K - $96K/yr

Case Manager, Patient Services -Rare Disease (West Coast Candidates)

Remote
Commercial
2mo ago
$75K - $96K/yr

Medical Science Liaison - Italy

Remote
Medical Affairs
3mo ago
Interview Prep Quick Facts
Portfolio: 3 approved products, 74 clinical trials
Top TAs: Rare Diseases, Neurology, Oncology
H-1B (2023): 4 approvals
SEC Filings: 2 available
Open Roles: 19 active jobs
Portfolio Health
Launch1 (33%)
Peak2 (67%)
3 total products
Therapeutic Area Focus
Rare Diseases
32 pipeline
Neurology
8 pipeline
Oncology
7 pipeline
Immunology
2 marketed
Nephrology
1 pipeline
Marketed
Pipeline

Financials (FY2025)

Revenue
$938M34%
R&D Spend
$667M(71%)2%
Net Income
-$627M
Cash
$780M

Hiring Trend

Actively Hiring
19
Open Roles
+6
Added
-3
Filled/Removed

Based on last 4 crawl cycles

Visa Sponsorship

Sponsors Work Visas
H-1B Petitions (FY2023)
4
Approved
0
Denied
100%
Rate

Source: USCIS H-1B Employer Data Hub