High Grade Glioma
Oncology
4
Pipeline Programs
4
Companies
4
Clinical Trials
2 recruiting
0
Approved Products
Pipeline by Development Stage
Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
3
0
1
0
0
0
Early DiscoveryClinical DevelopmentMarket
Competitive Landscape
4 companies ranked by most advanced pipeline stage
Trial Timeline
Clinical trial activity over time
2021
2022
2023
2024
2025
2026
2027
2028
2029
2030
2031
Rigel PharmaceuticalsOlutasidenib + TMZ
SonALAsenseSONALA-001
PTC TherapeuticsPTC596
Ipsennanoliposomal irinotecan
Clinical Trials (4)
Total enrollment: 82 patients across 4 trials
Study of Olutasidenib and Temozolomide in HGG
Start: Mar 2025Est. completion: Jun 2035
Phase 2Recruiting
Study of Sonodynamic Therapy in Participants with Recurrent High-Grade Glioma
Start: Mar 2021Est. completion: Mar 2028
Phase 1Recruiting
A Phase 1b Study of PTC596 in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma and High Grade Glioma
Start: Aug 2018Est. completion: Mar 202964 patients
Phase 1Active Not Recruiting
Study of Convection-Enhanced, Image-Assisted Delivery of Liposomal-Irinotecan In Recurrent High Grade Glioma
Start: Oct 2014Est. completion: May 202318 patients
Phase 1Completed
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Phase Legend
Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available
Key Insights
2 actively recruiting trials targeting 82 patients
4 companies competing in this space