Leigh Syndrome

1
Pipeline Programs
2
Companies
2
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
1
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

2 companies ranked by most advanced pipeline stage

PTC Therapeutics
1 program
1
EPI-743Phase 21 trial
Active Trials
NCT02352896Completed30Est. Oct 2023
Taysha Gene Therapies
1 program
NoneN/A1 trial
Active Trials
NCT05277363WithdrawnEst. May 2022

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
PTC TherapeuticsEPI-743
Taysha Gene TherapiesNone

Clinical Trials (2)

Total enrollment: 30 patients across 2 trials

Long-Term Safety and Efficacy Evaluation of EPI-743 in Children With Leigh Syndrome

Start: Jan 2014Est. completion: Oct 202330 patients
Phase 2Completed

A Study of the Natural Course of SURF1 Deficiency

Start: May 2022Est. completion: May 2022
N/AWithdrawn

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

2 companies competing in this space