Synovial Sarcoma
Oncology
3
Pipeline Programs
2
Companies
3
Clinical Trials
1 recruiting
0
Approved Products
Pipeline by Development Stage
Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
1
1
0
1
0
Early DiscoveryClinical DevelopmentMarket
Drug Modality Breakdown
Cell Therapy
3100%
+ 1 programs with unclassified modality
Competitive Landscape
2 companies ranked by most advanced pipeline stage
US WorldMedsKY - Louisville
3 programs1
1
afamitresgene autoleucelPhase 2Cell Therapy1 trial
Afamitresgene autoleucelPhase 1/2Cell Therapy1 trial
Non-conforming afamitresgene autoleucelN/ACell Therapy1 trial
Active Trials
Trial Timeline
Clinical trial activity over time
2021
2022
2023
2024
2025
2026
2027
2028
2029
2030
2031
US WorldMedsafamitresgene autoleucel
US WorldMedsAfamitresgene autoleucel
Clinical Trials (3)
Spearhead 1 Study in Subjects With Advanced Synovial Sarcoma or Myxoid/Round Cell Liposarcoma
Start: Aug 2019Est. completion: Apr 2038
Phase 2Active Not Recruiting
SPEARHEAD-3 Pediatric Study
Start: Sep 2023Est. completion: Jul 2038
Phase 1/2Recruiting
Expanded Access Protocol (EAP) for Nonconforming (NC) Afami-cel
N/AAvailable
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Phase Legend
Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available
Key Insights
1 late-stage (Phase 3) programs — potential near-term approvals
1 actively recruiting trials
Cell Therapy is the dominant modality (100% of programs)
2 companies competing in this space