Multiple Myeloma

Oncology
227
Pipeline Programs
30
Companies
45
Clinical Trials
12 recruiting
12
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
75
40
61
1
34
16
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Monoclonal Antibody
2856%
Cell Therapy
1326%
Small Molecule
714%
Peptide
12%
ADC
12%
+ 182 programs with unclassified modality

On Market (12)

Approved therapies currently available

U
BORTEZOMIBApproved
bortezomib
Unknown Company
Proteasome Inhibitor [EPC]intravenous, subcutaneous2022
Pfizer
ELREXFIOApproved
elranatamab-bcmm
Pfizer
injection2023
Bristol Myers Squibb
EMPLICITIApproved
elotuzumab
Bristol Myers Squibb
SLAMF7-directed Immunostimulatory Antibody [EPC]injection2015
U
LENALIDOMIDEApproved
lenalidomide
Unknown Company
Thalidomide Analog [EPC]oral2022
Takeda
NINLAROApproved
ixazomib
Takeda
oral2015
Bristol Myers Squibb
OPDIVOApproved
nivolumab
Bristol Myers Squibb
injection2015
Novartis
RECLASTApproved
zoledronic acid
Novartis
injection2007
Bristol Myers Squibb
REVLIMIDApproved
lenalidomide
Bristol Myers Squibb
Thalidomide Analog [EPC]oral2005
Sanofi
SARCLISAApproved
isatuximab
Sanofi
CD38-directed Cytolytic Antibody [EPC]injection2020
U
THALIDOMIDEApproved
thalidomide
Unknown Company
oral2023
Takeda
VELCADEApproved
bortezomib
Takeda
Proteasome Inhibitor [EPC]intravenous, subcutaneous2003
Novartis
ZOMETAApproved
zoledronic acid
Novartis
iv (infusion)2002

Competitive Landscape

67 companies ranked by most advanced pipeline stage

Bristol Myers Squibb
20 programs
5
1
6
4
1
IberdomidePhase 31 trial
IberdomidePhase 3
IsatuximabPhase 3Monoclonal Antibody
NivolumabPhase 3Monoclonal Antibody
Arlocabtagene AutoleucelPhase 2Cell Therapy1 trial
+15 more programs
Active Trials
NCT06160167Completed4,204Est. Aug 2024
NCT06698887Recruiting15Est. Mar 2031
NCT06154902Active Not Recruiting350Est. Dec 2027
+25 more trials
Takeda
13 programs
1
1
5
3
1
IGI, 10%Phase 31 trial
IxazomibPhase 31 trial
Ixazomib, thalidomide, & dexamethasonePhase 31 trial
CyclophosphamidePhase 21 trial
Daratumumab, Ixazomib, DexamethasonePhase 2
+8 more programs
Active Trials
NCT03984097Active Not Recruiting50Est. Mar 2026
NCT02976272Unknown60Est. Jan 2021
NCT02026505Completed11Est. Mar 2019
+16 more trials
Pfizer
11 programs
8
1
1
ElranatamabPhase 4Monoclonal Antibody1 trial
ELREXFIO(Elranatamab)Phase 2Monoclonal Antibody5 trials
ACTR087Phase 1
Investigational drugPhase 11 trial
SEA-BCMAPhase 11 trial
+6 more programs
Active Trials
NCT05238311No Longer Available
NCT00036140Completed
NCT03582033Terminated83Est. Nov 2023
+11 more trials
Novartis
NovartisBASEL, Switzerland
11 programs
6
4
1
zoledronic acidPhase 41 trial
LDE225Phase 21 trial
PTK787/ZK222584Phase 23 trials
PanobinostatPhase 2Small Molecule1 trial
panobinostatPhase 2Small Molecule1 trial
+6 more programs
Active Trials
NCT03549442Active Not Recruiting40Est. Mar 2036
NCT01680796Withdrawn0Est. Feb 2013
NCT00231166Completed33Est. May 2009
+9 more trials
Sanofi
8 programs
2
4
1
1
Carfilzomib Lenalidomide DexamethasonePhase 3
CellProtectPhase 21 trial
IsatuximabPhase 2Monoclonal Antibody1 trial
IsatuximabPhase 2Monoclonal Antibody1 trial
plerixaforPhase 21 trial
+3 more programs
Active Trials
NCT01233895Completed26Est. Sep 2008
NCT04558931Recruiting62Est. Dec 2032
NCT06517017Recruiting40Est. Nov 2027
+2 more trials
CASI Pharmaceuticals
CASI PharmaceuticalsBEIJING, China
4 programs
3
1
Melphalan Hydrochloride for InjectionPhase 41 trial
CID-103Phase 11 trial
ENMD-2076Phase 11 trial
melphalan hydrochloride for injectionPhase 11 trial
Active Trials
NCT04758767CompletedEst. Jan 2023
NCT00806065CompletedEst. Jan 2012
NCT05438394UnknownEst. Dec 2023
+1 more trials
Merit Medical
Merit MedicalSOUTH JORDAN, UT
1 program
1
Kyphoplasty/Vertebral AugmentationPhase 41 trial
Active Trials
NCT01410929Withdrawn
Amgen
16 programs
3
3
8
1
InductionPhase 32 trials
Belantamab mafodotinPhase 2ADC1 trial
BendamustinePhase 21 trial
CarfilzomibPhase 21 trial
CarfilzomibPhase 21 trial
+11 more programs
Active Trials
NCT04128475Terminated1,137Est. Apr 2021
NCT04151342Recruiting5,500Est. Dec 2029
NCT04220164Unknown500Est. Dec 2025
+23 more trials
Karyopharm Therapeutics
2
4
6
2
SelinexorPhase 31 trial
SelinexorPhase 31 trial
SelinexorPhase 21 trial
SelinexorPhase 21 trial
SelinexorPhase 21 trial
+10 more programs
Active Trials
NCT07215832Available
NCT02831686CompletedEst. Nov 2020
NCT07200102Not Yet RecruitingEst. Mar 2031
+11 more trials
AbbVie
11 programs
2
1
4
1
3
EtentamigPhase 31 trial
LenalidomidePhase 31 trial
NivolumabPhase 3Monoclonal Antibody4 trials
EtentamigPhase 2/31 trial
DexamethasonePhase 25 trials
+6 more programs
Active Trials
NCT07409246Not Yet Recruiting127Est. Nov 2031
NCT06896916Recruiting135Est. Mar 2036
NCT06223516Recruiting55Est. Dec 2027
+17 more trials
Heidelberg Pharma
1
1
5
EmendPhase 31 trial
IberdomidePhase 31 trial
IsatuximabPhase 3Monoclonal Antibody1 trial
LenalidomidePhase 31 trial
elotuzumabPhase 3Monoclonal Antibody1 trial
+3 more programs
Active Trials
NCT07044427Recruiting60Est. Dec 2026
NCT04879043Recruiting78Est. May 2026
NCT02237261Completed46Est. Oct 2018
+5 more trials
Regeneron
RegeneronTARRYTOWN, NY
5 programs
2
1
1
LinvoseltamabPhase 3Monoclonal Antibody1 trial
LinvoseltamabPhase 2Monoclonal Antibody1 trial
LinvoseltamabPhase 1/2Monoclonal Antibody1 trial
LinvoseltamabPhase 1/2Monoclonal Antibody1 trial
REGN5458N/A1 trial
Active Trials
NCT05164250Approved For Marketing
NCT05828511Recruiting149Est. Nov 2035
NCT03761108Recruiting387Est. Jun 2033
+2 more trials
J&
1
2
2
BortezomibPhase 31 trial
VelcadePhase 31 trial
VELCADEPhase 1/21 trial
VelcadePhase 1/21 trial
bortezomibPhase 15 trials
Active Trials
NCT06142396Recruiting30Est. Nov 2027
NCT06577025Active Not Recruiting43Est. Sep 2030
NCT06353022Active Not Recruiting103Est. Jun 2030
+6 more trials
Qilu Pharmaceutical
Qilu PharmaceuticalChina - Jinan
3 programs
1
2
PomalidomidePhase 31 trial
QL2109Phase 31 trial
QL2109Phase 11 trial
Active Trials
NCT07400744Not Yet RecruitingEst. Oct 2026
NCT05236621UnknownEst. Dec 2023
NCT06742138Not Yet RecruitingEst. Dec 2028
Oncopeptides
OncopeptidesSweden - Stockholm
3 programs
1
1
1
MelflufenPhase 31 trial
Melphalan flufenamidePhase 2
Melphalan flufenamidePhase 1/21 trial
Active Trials
NCT03481556TerminatedEst. Feb 2022
NCT03151811TerminatedEst. Feb 2023
OD
3 programs
1
2
ThalidomidePhase 3
Vincristine, DOXILPhase 3
bortezomib; pegylated liposomal doxorubicinPhase 2
M&
Merck & Co.RAHWAY, NJ
2 programs
1
1
InductionPhase 35 trials
M3258Phase 11 trial
Active Trials
NCT04075721Terminated10Est. Apr 2021
NCT07135453Not Yet Recruiting70Est. Aug 2027
NCT06686381Not Yet RecruitingEst. Aug 2028
+3 more trials
BioLineRx
BioLineRxIsrael - Modi’in
2 programs
1
1
BL-8040 1.25 mg/kg + G-CSFPhase 31 trial
MotixafortidePhase 1Peptide1 trial
Active Trials
NCT06547112CompletedEst. Aug 2025
NCT03246529Active Not RecruitingEst. Sep 2029
Arcellx
2 programs
1
1
Anitocabtagene AutoleucelPhase 3Cell Therapy
anitocabtagene-autoleucelPhase 2Cell Therapy
AS
2 programs
1
1
MasitinibPhase 3Small Molecule1 trial
masitinibPhase 2Small Molecule1 trial
Active Trials
NCT00866138CompletedEst. Jan 2011
NCT01470131TerminatedEst. Feb 2017
Knight Therapeutics
1
LenalidomidePhase 31 trial
Active Trials
NCT01208662Active Not Recruiting729Est. Dec 2026
Swedish Orphan Biovitrum
1
Palifermin before onlyPhase 31 trial
Active Trials
NCT00434161CompletedEst. May 2012
Pierre Fabre
Pierre FabreFrance - Aignan
1 program
1
bortezomibPhase 3
Teva
8 programs
1
5
2
BeEAMPhase 21 trial
SDX-101Phase 21 trial
CEP-18770Phase 1/21 trial
CEP-18770Phase 1/21 trial
Modakafusp AlfaPhase 1/22 trials
+3 more programs
Active Trials
NCT03524235Completed20Est. Nov 2024
NCT01023880Terminated62Est. Jan 2013
NCT01348919Completed11Est. Mar 2013
+6 more trials
Genentech
7 programs
4
2
BevacizumabPhase 2Monoclonal Antibody1 trial
BortezomibPhase 21 trial
CevostamabPhase 1Monoclonal Antibody1 trial
DFRF4539APhase 11 trial
SGN-40Phase 1
+2 more programs
Active Trials
NCT01410981Completed73Est. Jun 2014
NCT04910568Active Not Recruiting126Est. Dec 2029
NCT01432353Completed39Est. Apr 2014
+2 more trials
Cartesian Therapeutics
4 programs
3
1
Descartes 11Phase 21 trial
Descartes-08Phase 11 trial
Descartes-11Phase 11 trial
Descartes-25Phase 11 trial
Active Trials
NCT03448978TerminatedEst. Jun 2021
NCT03994705TerminatedEst. Jun 2021
NCT05113342TerminatedEst. Nov 2024
+1 more trials
GS
4 programs
1
2
1
anitocabtagene-autoleucelPhase 2Cell Therapy1 trial
milatuzumabPhase 1/2Monoclonal Antibody1 trial
milatuzumabPhase 1/2Monoclonal Antibody
NY-ESO-1 redirected autologous T cells with CRISPR edited endogenous TCR and PD-1Phase 11 trial
Active Trials
NCT03399448Terminated3Est. Oct 2020
NCT00421525Completed25Est. Jun 2009
NCT05396885Active Not Recruiting136Est. Dec 2026
Precision BioSciences
4 programs
3
1
Melphalan flufenamidePhase 21 trial
BCMA CAR-T cellsPhase 1/2Cell Therapy1 trial
BCMA CAR-T cellsPhase 1/2Cell Therapy1 trial
BCMA targeted prime CAR-T cellsPhase 1/2Cell Therapy1 trial
Active Trials
NCT04271644Recruiting80Est. Jul 2027
NCT04272151Unknown40Est. Jul 2024
NCT04776330Recruiting80Est. Jul 2027
+1 more trials
Roche
RocheSTAVANGER NORWAY, Norway
3 programs
2
1
BevacizumabPhase 2Monoclonal Antibody1 trial
ForimtamigPhase 11 trial
RO6870810Phase 13 trials
Active Trials
NCT04557150Active Not Recruiting225Est. Feb 2026
NCT03068351Completed24Est. Aug 2019
NCT02308761Completed26Est. Aug 2017
+2 more trials
E
2 programs
1
1
PalonosetronPhase 21 trial
Denileukin DiftitoxPhase 11 trial
Active Trials
NCT01251952Terminated2Est. May 2013
NCT00306735Completed75Est. Dec 2007

+37 more companies

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
2030
2031
Merck & Co.Induction
PfizerElranatamab
AbbVieDexamethasone
BayerRadium-223 dichloride
CASI PharmaceuticalsMelphalan Hydrochloride for Injection
BayerRadium-223 dichloride
Johnson & Johnsonbortezomib
Merck & Co.Induction
Merit MedicalKyphoplasty/Vertebral Augmentation
Merck & Co.Induction
Novartiszoledronic acid
TakedaIGI, 10%
RegeneronLinvoseltamab
PfizerElranatamab
Qilu PharmaceuticalQL2109

Showing 15 of 44 trials with date data

Clinical Trials (45)

Total enrollment: 16,550 patients across 45 trials

Induction of Cross-protective Antibodies for Serogroup 33 by Pneumococcal Conjugate Vaccines

Start: Mar 2026Est. completion: Aug 202770 patients
Phase 4Not Yet Recruiting

Elranatamab Post Trial Access Study for Participants With Multiple Myeloma (MM)

Start: Oct 2023Est. completion: Feb 203280 patients
Phase 4Recruiting
NCT05990829AbbVieDexamethasone

Compare the Efficacy of VItrectomy Combined With DExamethasone Implant Versus With Aflibercept in DME Patients Diagnosed by Intraoperative OCT (the VIDEO Study): Study Protocol for a Randomized Controlled Trial

Start: Oct 2023Est. completion: Apr 202564 patients
Phase 4Unknown
NCT04597125BayerRadium-223 dichloride

RADIANT: A Study of Radium-223 Dichloride (Xofigo) vs Enzalutamide or Abiraterone (ARPIs, Androgen Receptor Pathway Inhibitors) in Patients With Prostate Cancer That Has Spread to the Bones (mCRPC, Metastatic Castration-Resistant Prostate Cancer)

Start: Nov 2020Est. completion: Oct 2026654 patients
Phase 4Active Not Recruiting
NCT06425276CASI PharmaceuticalsMelphalan Hydrochloride for Injection

Evaluate Safety and Efficacy of High-dose Melphalan HCL for Injection in MM Patients With Auto-HSC Transplantation

Start: Jul 2020Est. completion: Sep 2021
Phase 4Completed
NCT02312960BayerRadium-223 dichloride

Radium-223 Dichloride Long-term Follow-up Program

Start: Dec 2014Est. completion: Jan 2024255 patients
Phase 4Completed

A Pharmacokinetic Study of Bortezomib in Taiwanese Participants With Multiple Myeloma

Start: Dec 2014Est. completion: Jul 201518 patients
Phase 4Completed

Low-dose Gonal-f® in Ovulation Induction

Start: Jul 2013Est. completion: Nov 2014
Phase 4Terminated
NCT01410929Merit MedicalKyphoplasty/Vertebral Augmentation

Evaluation of Vertebral Compression Fracture Fixation With RF Kyphoplasty in Patients With Multiple Myeloma

Start: May 2011
Phase 4Withdrawn

A Randomized Acceptability and Safety Study of Suboxone Induction in Heroin Users (P05042)(COMPLETED)

Start: Feb 2008Est. completion: Dec 2009188 patients
Phase 4Completed
NCT00622505Novartiszoledronic acid

Zoledronic Acid Treatment (Every 4 or 12 Weeks) to Prevent Skeletal Complications in Advanced Multiple Myeloma Participants

Start: Nov 2007Est. completion: Apr 2012121 patients
Phase 4Completed

UFT/LV Maintenance Vs Observation in Metastatic Breast Cancer Responsive to Chemotherapy

Phase 3Unknown

A Study of Gammagard Liquid (Immune Globulin Infusion, 10%) to Prevent Infections in Adults With Multiple Myeloma

Start: Jan 2026Est. completion: Sep 2028183 patients
Phase 3Recruiting

A Study to Learn How Safe and How Well Linvoseltamab Works Compared to Standard Treatment in Adult Patients With Multiple Myeloma Who Are Not Eligible for Transplant

Start: Dec 2025Est. completion: Dec 20361,000 patients
Phase 3Recruiting

Elranatamab/Lenalidomide Consolidation and/or Elranatamab Maintenance Versus Standard of Care After D-VRd Induction in Transplant-eligible NDMM Patients

Start: Jul 2025Est. completion: May 2036824 patients
Phase 3Recruiting

To Evaluate the Efficacy and Safety of QL2109 and DARZALEX FASPRO® in Multiple Myeloma

Start: Jan 2025Est. completion: Dec 2028
Phase 3Not Yet Recruiting

Study Assessing Activity of Intravenous (IV) Etentamig Monotherapy Versus Standard Available Therapies in Adult Participants With Relapsed or Refractory Multiple Myeloma

Start: May 2024Est. completion: Dec 2027380 patients
Phase 3Recruiting

Iberdomide vs. Iberdomide Plus Isatuximab Maintenance Therapy Post ASCT in Newly Diagnosed Multiple Myeloma

Start: Apr 2024Est. completion: Jun 2029411 patients
Phase 3Recruiting

MagnetisMM-32: A Study to Learn About the Study Medicine Called Elranatamab in People With Multiple Myeloma (MM) That Has Come Back After Taking Other Treatments (Including Prior Treatment With an Anti-CD38 Antibody and Lenalidomide)

Start: Feb 2024Est. completion: Dec 2027492 patients
Phase 3Recruiting

A Study Comparing Talquetamab Plus Pomalidomide, Talquetamab Plus Teclistamab, and Elotuzumab, Pomalidomide, and Dexamethasone or Pomalidomide, Bortezomib, and Dexamethasone in Participants With Relapsed or Refractory Myeloma Who Have Received an Anti-CD38 Antibody and Lenalidomide

Start: Jan 2024Est. completion: Mar 2028795 patients
Phase 3Recruiting

A Study of Daratumumab, Bortezomib, Lenalidomide and Dexamethasone (DVRd) Followed by Ciltacabtagene Autoleucel Versus Daratumumab, Bortezomib, Lenalidomide and Dexamethasone (DVRd) Followed by Autologous Stem Cell Transplant (ASCT) in Participants With Newly Diagnosed Multiple Myeloma

Start: Oct 2023Est. completion: Aug 2040759 patients
Phase 3Active Not Recruiting

A Study to Compare Iberdomide Maintenance Versus Lenalidomide Maintenance Therapy Following Autologous Stem Cell Transplant in Participants With Newly Diagnosed Multiple Myeloma

Start: Jun 2023Est. completion: Jan 20361,216 patients
Phase 3Recruiting

Lenalidomide, Bortezomib and Dexamethasone Induction Therapy With Either Intravenous or Subcutaneous Isatuximab in Patients With Newly Diagnosed Multiple Myeloma

Start: Apr 2023Est. completion: Jan 2026514 patients
Phase 3Completed

A Study Comparing Teclistamab Monotherapy Versus Pomalidomide, Bortezomib, Dexamethasone (PVd) or Carfilzomib, Dexamethasone (Kd) in Participants With Relapsed or Refractory Multiple Myeloma

Start: Mar 2023Est. completion: Aug 2031614 patients
Phase 3Active Not Recruiting

A Study to Learn About Effects of the Combination of Elranatamab, Daratumumab and Lenalidomide Compared With Daratumumab, Lenalidomide, and Dexamethasone in Patients With Newly Diagnosed Multiple Myeloma Who Are Not Candidates for Transplant or Who Will Not Receive a Transplant as Initial Therapy

Start: Nov 2022Est. completion: Oct 20331,116 patients
Phase 3Recruiting

A Study of Combination of Selinexor, Pomalidomide, and Dexamethasone (SPd) Versus Elotuzumab, Pomalidomide, and Dexamethasone (EloPd) in Subject With Previously Treated Multiple Myeloma

Start: Apr 2022Est. completion: Mar 2029
Phase 3Active Not Recruiting

Study With Elranatamab Versus Lenalidomide in Patients With Newly Diagnosed Multiple Myeloma After Transplant

Start: Mar 2022Est. completion: Oct 2029811 patients
Phase 3Active Not Recruiting

MInimal Residual Disease Adapted Strategy

Start: Dec 2021Est. completion: Sep 2028791 patients
Phase 3Active Not Recruiting

A Study of Teclistamab in Combination With Daratumumab Subcutaneously (SC) (Tec-Dara) Versus Daratumumab SC, Pomalidomide, and Dexamethasone (DPd) or Daratumumab SC, Bortezomib, and Dexamethasone (DVd) in Participants With Relapsed or Refractory Multiple Myeloma

Start: Oct 2021Est. completion: Dec 2028587 patients
Phase 3Active Not Recruiting
NCT04976777AbbVieDexamethasone

A Study to Evaluate an Updated Dexamethasone Intravitreal (Into the Eye) Applicator in Adult Participants With Macular Edema Due to Diseases of the Retina

Start: Oct 2021Est. completion: Feb 202254 patients
Phase 3Completed

A Study to Learn About the Study Medicine Elranatamab Alone and With Daratumumab in People With Multiple Myeloma Who Have Received Other Treatments

Start: Oct 2021Est. completion: May 2027944 patients
Phase 3Recruiting

A Study of Bortezomib, Lenalidomide and Dexamethasone (VRd) Followed by Cilta-cel, a CAR-T Therapy Directed Against BCMA Versus VRd Followed by Lenalidomide and Dexamethasone (Rd) Therapy in Participants With Newly Diagnosed Multiple Myeloma for Whom ASCT is Not Planned as Initial Therapy

Start: Aug 2021Est. completion: Sep 2036743 patients
Phase 3Active Not Recruiting

A Study of the Efficacy and Safety of Pomalidomide Capsules Combined With Low-Dose Dexamethasone in Subjects With Relapsed and Refractory Multiple Myeloma

Start: Jan 2021Est. completion: Dec 2023
Phase 3Unknown
NCT04483739AmgenCarfilzomib

Isa-KRd vs KRd in Newly Diagnosed Multiple Myeloma Patients Eligible for Autologous Stem Cell Transplantation (IsKia TRIAL)

Start: Sep 2020Est. completion: Dec 2032302 patients
Phase 3Active Not Recruiting

A Study Comparing JNJ-68284528, a CAR-T Therapy Directed Against B-cell Maturation Antigen (BCMA), Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) or Daratumumab, Pomalidomide and Dexamethasone (DPd) in Participants With Relapsed and Lenalidomide-Refractory Multiple Myeloma

Start: Jun 2020Est. completion: Apr 2029419 patients
Phase 3Active Not Recruiting
NCT03859427AmgenCarfilzomib

A Study Comparing Once-weekly vs Twice-weekly Carfilzomib in Combination With Lenalidomide and Dexamethasone in Subjects With Relapsed or Refractory Multiple Myeloma

Start: May 2019Est. completion: Mar 2023454 patients
Phase 3Completed

Study of Oral Ixazomib Maintenance Therapy After Initial Therapy in Participants With Newly Diagnosed Multiple Myeloma Not Treated With Stem Cell Transplantation (SCT)

Start: Jan 2019Est. completion: Dec 202337 patients
Phase 3Completed

Trial on the Effect of Isatuximab to Lenalidomide/Bortezomib/Dexamethasone (RVd) Induction and Lenalidomide Maintenance in Patients With Newly Diagnosed Myeloma (GMMG HD7)

Start: Oct 2018Est. completion: Jun 2028662 patients
Phase 3Active Not Recruiting
NCT03246529BioLineRxBL-8040 1.25 mg/kg + G-CSF

A Phase III, Safety, Tolerability and Efficacy of Combination Treatment of BL-8040 and Granulocyte Colony Stimulating Factor (G-CSF) as Compared to Placebo and G-CSF for the Mobilization of Hematopoietic Stem Cells for Autologous Transplantation in Subjects With Multiple Myeloma (MM)

Start: Mar 2018Est. completion: Sep 2029
Phase 3Active Not Recruiting
NCT03334487AbbVieDexamethasone

Study Evaluating the Safety of Rovalpituzumab Tesirine for Third-Line and Later Treatment of Subjects With Relapsed or Refractory Small Cell Lung Cancer

Start: Mar 2018Est. completion: Dec 20180
Phase 3Withdrawn

A Study to Evaluate the Efficacy and Safety of Daratumumab in Combination With Cyclophosphamide, Bortezomib and Dexamethasone (CyBorD) Compared to CyBorD Alone in Newly Diagnosed Systemic Amyloid Light-chain (AL) Amyloidosis

Start: Oct 2017Est. completion: Nov 2024416 patients
Phase 3Completed

A Study of Melphalan Flufenamide (Melflufen)-Dex or Pomalidomide-dex for RRMM Patients Refractory to Lenalidomide

Start: Jun 2017Est. completion: Feb 2023
Phase 3Terminated

Bortezomib, Selinexor, and Dexamethasone in Patients With Multiple Myeloma

Start: May 2017Est. completion: May 2022
Phase 3Completed
NCT03562169TakedaIxazomib, thalidomide, & dexamethasone

The Role of Ixazomib in Autologous Stem Cell Transplant in Relapsed Myeloma - Myeloma XII (ACCoRd)

Start: Mar 2017Est. completion: Mar 2027406 patients
Phase 3Recruiting

An Investigational Immuno-therapy Study of Nivolumab, Pomalidomide and Dexamethasone Combinations in Patients With Multiple Myeloma

Start: Aug 2016Est. completion: Mar 2022170 patients
Phase 3Completed

Related Jobs in Oncology

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

34 late-stage (Phase 3) programs — potential near-term approvals
12 actively recruiting trials targeting 16,550 patients
30 companies competing in this space