Acute Respiratory Failure

Respiratory
1
Pipeline Programs
3
Companies
6
Clinical Trials
2 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
0
0
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

3 companies ranked by most advanced pipeline stage

Design Therapeutics
2 programs
1
Novel restraintPhase 11 trial
ExersidesN/A1 trial
Active Trials
NCT04067622CompletedEst. Dec 2021
NCT03621475CompletedEst. Apr 2019
Hamilton medical
Hamilton medicalSwitzerland - Bonaduz
3 programs
INTELLiVENT-ASVN/A1 trial
OptimizedN/A1 trial
close-loop synchronization controller with SPONT modeN/A1 trial
Active Trials
NCT04400643TerminatedEst. Jul 2022
NCT03787173CompletedEst. Apr 2024
NCT05731024RecruitingEst. Dec 2025
Eko Devices
Eko DevicesCA - Emeryville
1 program
AuscultationN/A1 trial
Active Trials
NCT05144633Recruiting100Est. Apr 2025

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Design TherapeuticsNovel restraint
Hamilton medicalclose-loop synchronization controller with SPONT mode
Eko DevicesAuscultation
Hamilton medicalINTELLiVENT-ASV
Design TherapeuticsExersides
Hamilton medicalOptimized

Clinical Trials (6)

Total enrollment: 100 patients across 6 trials

NCT03621475Design TherapeuticsNovel restraint

Novel Arm Restraint in the Intensive Care Unit

Start: Oct 2018Est. completion: Apr 2019
Phase 1Completed
NCT05731024Hamilton medicalclose-loop synchronization controller with SPONT mode

Closed-loop Synchronization Versus Conventional Synchronization

Start: Feb 2023Est. completion: Dec 2025
N/ARecruiting
NCT05144633Eko DevicesAuscultation

Blue Protocol and Eko Artificial Intelligence Are Best (BEA-BEST)

Start: Sep 2021Est. completion: Apr 2025100 patients
N/ARecruiting
NCT04400643Hamilton medicalINTELLiVENT-ASV

EASiVENT Study Comparing INTELLiVENT-ASV vs Non Automated Ventilation in Adult ICU Patients

Start: Mar 2020Est. completion: Jul 2022
N/ATerminated
NCT04067622Design TherapeuticsExersides

Novel Arm Restraint For Critically Ill Patients To Reduce Immobility, Sedation, Agitation and Cognitive Impairment

Start: Sep 2019Est. completion: Dec 2021
N/ACompleted
NCT03787173Hamilton medicalOptimized

Patient-ventilator Synchronisation Study for Intensive Care Unit Patients

Start: Apr 2019Est. completion: Apr 2024
N/ACompleted

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Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

2 actively recruiting trials targeting 100 patients
3 companies competing in this space

Related Indications

Asthma(378)Pulmonary Disease, Chronic Obstructive(263)Chronic Obstructive Pulmonary Disease(123)Idiopathic Pulmonary Fibrosis(90)COPD(74)Chronic Obstructive Pulmonary Disease (COPD)(38)Pulmonary Embolism(27)Respiratory Syncytial Virus Infections(26)Severe Asthma(21)Lung Diseases, Interstitial(19)