Rigel Pharmaceuticals

Rigel Pharmaceuticals(RIGL)

SOUTH SAN FRANCISCO, CA
Pharmaceutical

Focus: Small Molecules

Rigel Pharmaceuticals is a life sciences company focused on Small Molecules.

Neurology
Funding Stage
PUBLIC
Open Jobs
0

Products & Portfolio (3)

Pipeline & Clinical Trials

Fostamatinib disodium 100 mg
Immune Thrombocytopenic Purpura
N/A
Clinical Trials (1)
NCT03363334Expanded Access of Fostamatinib in Patients With Persistent or Chronic Relapsing/Refractory ITP
N/A
Fostamatinib
ITP
N/A
Clinical Trials (1)
NCT04904276Observational Study of Fostamatinib as Second Line Therapy in Adult Patients With Immune Thrombocytopenia (ITP) and Insufficient Response to a Prior Therapy
N/A
R348 Ophthalmic Solution, 0.2%
Keratoconjunctivitis Sicca
Phase 1
Clinical Trials (1)
NCT01733992A Safety, Tolerability and Pharmacokinetics Study of R932348 Eye Drops in Patients With Dry Eye Disease
Phase 1
Clinical Trials (1)
NCT06233110Ruxolitinib Plus Fostamatinib for Steroid Refractory cGvHD
Phase 1
Fostamatinib in combination with chemotherapy
Pancreatic Ductal Adenocarcinoma (PDAC)
Phase 1
Clinical Trials (1)
NCT06639724Perioperative Fostamatinib With Gemcitabine and Nab-paclitaxel in Resectable Pancreatic Cancer
Phase 1
Olutasidenib Investigational Agent Administration
Acute Myeloid Leukemia
Phase 1
Clinical Trials (1)
NCT07130695Olutasidenib Single Plus Combo Therapy in IDH1mut AML After Induction and Consolidation
Phase 1
Fostamatinib 100 mg bid and Paclitaxel
Ovarian Cancer
Phase 1
Clinical Trials (1)
NCT03246074Clinical Trial of Combined Fostamatinib and Paclitaxel in Ovarian Cancer
Phase 1
Phase 1/2
Clinical Trials (1)
NCT05308264Study of R289 in Patients With Lower-risk Myelodysplastic Syndromes (LR MDS)
Phase 1/2
Ruxolitinib
Coronavirus
Phase 1/2
Clinical Trials (1)
NCT06445959Phase 1b/2 Study of Decitabine and Venetoclax in Combination With the Targeted Mutant IDH1 Inhibitor Olutasidenib
Phase 1/2
fostamatinib
Lymphoma
Phase 1/2
Clinical Trials (1)
NCT00446095Efficacy and Safety Study of Fostamatinib Tablets to Treat B-cell Lymphoma
Phase 1/2
Clinical Trials (1)
NCT06564207Fostamatinib for Treating Acute Respiratory Distress Syndrome (ARDS) in Hospitalized Adults
Phase 2
Placebo
Asthma
Phase 2
Clinical Trials (1)
NCT01591044A Safety and Efficacy Study of Inhaled R940343 in Patients With Mild to Moderate Asthma
Phase 2
Fostamatinib disodium
Rheumatoid Arthritis
Phase 2
Clinical Trials (1)
NCT00665626Efficacy and Safety Study of R935788 Tablets to Treat Rheumatoid Arthritis (Taski-3)
Phase 2
R348 Ophthalmic Solution, 0.2%
Keratoconjunctivitis Sicca
Phase 2
Clinical Trials (1)
NCT01900249To Assess the Safety and Efficacy of R932348 Ophthalmic Solutions in Patients With Keratoconjunctivitis Sicca
Phase 2
Phase 2
Clinical Trials (1)
NCT02612558A Safety and Efficacy Study of R935788 in the Treatment of Warm Antibody Autoimmune Hemolytic Anemia (AIHA)
Phase 2
Olutasidenib + TMZ
High Grade Glioma
Phase 2
Clinical Trials (1)
NCT06161974Study of Olutasidenib and Temozolomide in HGG
Phase 2
Olutasidenib
Targeted Therapy
Phase 2
Clinical Trials (1)
NCT07032727Olutasidenib Combined With Co-targeted Therapy in Relapsed or Refractory IDH1-mutated Myeloid Malignancies Harboring Activated Signaling Pathway Mutations
Phase 2
Fostamatinib Disodium tablet 100 mg
IGA Nephropathy
Phase 2
Clinical Trials (1)
NCT02433236Open Label Study of Fostamatinib in the Treatment of IgA Nephropathy
Phase 2
Phase 2
Fostamatinib Disodium
Systemic Lupus Erythematosus
Phase 2
Clinical Trials (1)
NCT00752999Efficacy and Safety Study of R935788 Tablets to Treat Systemic Lupus Erythematosus
Phase 2
Clinical Trials (1)
NCT01597050Safety and Efficacy of Topical R333 in Patients With Discoid Lupus Erythematosus (DLE) and Systemic Lupus Erythematosus (SLE) Lesions
Phase 2
Fostamatinib Disodium / R935788
Purpura, Thrombocytopenic, Idiopathic
Phase 2
Clinical Trials (1)
NCT00706342Pilot Study of Fostamatinib Disodium/R935788 for the Treatment of Adult Refractory Immune Thrombocytopenic Purpura (ITP)
Phase 2
Clinical Trials (1)
NCT00326339Treatment of Arthritis With Syk Kinase Inhibition (TASKI-1)
Phase 2
Phase 2
Clinical Trials (1)
NCT06782542Olutasidenib, Venetoclax, and Azacitidine in IDH1 Mutated Newly Diagnosed Acute Myeloid Leukemia Patients Eligible for Intensive Induction Chemotherapy
Phase 2
Phase 2
Clinical Trials (1)
NCT06566742A Phase 2 Study Evaluating Olutasidenib in Patients With IDH1-mutated Clonal Cytopenia of Undetermined Significance and Lower-risk Myelodysplastic/Syndromes/Chronic Myelomonocytic Leukemia.
Phase 2
Clinical Trials (1)
NCT001150897 Day Study of Mast Cell Inhibitor, R926112, in Patients With Symptomatic Seasonal Allergic Rhinitis
Phase 2
Fostamatinib disodium
Rheumatoid Arthritis
Phase 2
Clinical Trials (1)
NCT00665925Efficacy and Safety Study of R935788 Tablets to Treat Rheumatoid Arthritis
Phase 2
Fostamatinib
Myelofibrosis
Phase 2
Clinical Trials (1)
NCT04543279Fostamatinib as a Single Agent or in Combination With Ruxolitinib for Treatment of Patients With Myelofibrosis With Severe Thrombocytopenia
Phase 2
Fostamatinib Disodium
T Cell Lymphoma
Phase 2
Clinical Trials (1)
NCT00798096Efficacy and Safety Study of Fostamatinib Disodium Tablets to Treat T-Cell Lymphoma
Phase 2
Phase 2
Clinical Trials (1)
NCT05040698Study of the Effect of Fostamatinib Upon Cutaneous Inflammation in the Setting of Hidradenitis Suppurativa
Phase 2
Clinical Trials (1)
NCT06597734A Phase 2 Study Evaluating Olutasidenib in Combination With Hypomethylating Agents in Patients With IDH1-mutated Higher-risk Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia, or Advanced Myeloproliferative Neoplasm
Phase 2
Fostamatinib 150 mg
IGA Nephropathy
Phase 2
Clinical Trials (1)
NCT02112838Safety and Efficacy Study of Fostamatinib to Treat Immunoglobin A (IgA) Nephropathy
Phase 2
R348 Ophthalmic Solution, 0.2%
Chronic Graft-versus-host Disease
Phase 2
Clinical Trials (1)
NCT02040623Safety and Efficacy Study of R932348 Ophthalmic Solution in Chronic Ocular Graft Versus Host Disease Patients(DROPS-2)
Phase 2
Fostamatinib
Covid19
Phase 3
Clinical Trials (1)
NCT04629703Double-Blind, Randomized, Placebo-Controlled, Multi-Center Phase 3 Study to Evaluate the Efficacy and Safety of Fostamatinib in COVID-19 Subjects
Phase 3
Phase 3
Clinical Trials (1)
NCT04138927A Phase 3 Open Label Extension Study of Fostamatinib Disodium in the Treatment of Warm Antibody Autoimmune Hemolytic Anemia
Phase 3
Fostamatinib disodium
Immune Thrombocytopenic Purpura
Phase 3
Clinical Trials (1)
NCT02076399A Efficacy and Safety Study of R935788 in the Treatment of Persistent/Chronic Immune Thrombocytopenic Purpura (ITP)
Phase 3
Fostamatinib Disodium
Immune Thrombocytopenic Purpura
Phase 3
Clinical Trials (1)
NCT02076412A Efficacy and Safety Study of Fostamatinib in the Treatment of Persistent/Chronic Immune Thrombocytopenic Purpura (ITP)
Phase 3
Fostamatinib Disodium
Immune Thrombocytopenic Purpura
Phase 3
Clinical Trials (1)
NCT02077192Open Label Study of R788 in the Treatment of Persistent/Chronic Immune Thrombocytopenic Purpura (ITP)
Phase 3
Phase 3
Clinical Trials (1)
NCT03764618A Phase 3, Multi-Center, Randomized, Double-Blind, Placebo-Controlled, Study of Fostamatinib Disodium in the Treatment of wAIHA
Phase 3
imiquimod 5% cream
Actinic Keratoses
Phase 4
Clinical Trials (1)
NCT00774787Topical Imiquimod Cream in Combination With Cryotherapy for the Treatment of Actinic Keratoses
Phase 4

Open Jobs (0)

No open positions listed yet. Check their careers page directly.

Interview Prep Quick Facts
Portfolio: 3 approved products, 39 clinical trials
Top TAs: Oncology
SEC Filings: 2 available
Portfolio Health
Peak3 (100%)
3 total products
Therapeutic Area Focus
Oncology
1 marketed
Marketed
Pipeline

Financials (FY2025)

Revenue
$117M3%
R&D Spend
$25M(21%)59%
Net Income
-$25M
Cash
$57M