Actinic Keratoses

4
Pipeline Programs
4
Companies
4
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
1
1
0
0
2
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

4 companies ranked by most advanced pipeline stage

Pierre Fabre
Pierre FabreFrance - Aignan
1 program
1
5-fluorouracil 4%Phase 41 trial
Active Trials
NCT04875026Completed146Est. Jan 2022
Rigel Pharmaceuticals
Rigel PharmaceuticalsSOUTH SAN FRANCISCO, CA
1 program
1
imiquimod 5% creamPhase 41 trial
Active Trials
NCT00774787CompletedEst. Mar 2010
AP
Amryt PharmaUK - London
1 program
1
Oleogel-S10 100 mg/gPhase 21 trial
Active Trials
NCT00786994Completed165Est. Nov 2010
ME Therapeutics
ME TherapeuticsNEW YORK, NY
1 program
1
AVX001Phase 1/21 trial
Active Trials
NCT05164393UnknownEst. Mar 2022

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Pierre Fabre5-fluorouracil 4%
Rigel Pharmaceuticalsimiquimod 5% cream
Amryt PharmaOleogel-S10 100 mg/g
ME TherapeuticsAVX001

Clinical Trials (4)

Total enrollment: 311 patients across 4 trials

NCT04875026Pierre Fabre5-fluorouracil 4%

Frequency and Intensity of Local Reactions in Patients Treated With 4% 5-FU vs 4% 5-FU Associated With an Emollient Cream: a Randomised, Controlled Clinical Trial

Start: Feb 2021Est. completion: Jan 2022146 patients
Phase 4Completed

Topical Imiquimod Cream in Combination With Cryotherapy for the Treatment of Actinic Keratoses

Start: Oct 2008Est. completion: Mar 2010
Phase 4Completed
NCT00786994Amryt PharmaOleogel-S10 100 mg/g

The Efficacy and Tolerability of Oleogel-S-10 in Patients With Actinic Keratoses

Start: Oct 2008Est. completion: Nov 2010165 patients
Phase 2Completed

Phase I/IIa Trial to Evaluate AVX001 Gel in Doses of 1% or 3% Compared With Vehicle Over Four Weeks of Field-directed Treatment Period in Adult Subjects With AK

Start: Nov 2021Est. completion: Mar 2022
Phase 1/2Unknown

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

4 companies competing in this space