Acute Myeloid Leukemia

Oncology
191
Pipeline Programs
30
Companies
50
Clinical Trials
11 recruiting
5
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
94
33
41
2
16
5
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Small Molecule
1856%
Monoclonal Antibody
619%
ADC
619%
Cell Therapy
26%
+ 165 programs with unclassified modality

On Market (5)

Approved therapies currently available

Teva
CYTOSAR-UApproved
cytarabine
Teva
injection1998
Pfizer
DAURISMOApproved
glasdegib
Pfizer
Hedgehog Pathway Inhibitor [EPC]oral2018
U
DEPOCYTApproved
cytarabine
Unknown Company
injection1999
Teva
TRISENOXApproved
arsenic trioxide
Teva
injection2000
Astellas
XOSPATAApproved
gilteritinib
Astellas
oral2018

Competitive Landscape

67 companies ranked by most advanced pipeline stage

Pfizer
20 programs
8
4
4
1
1
GlasdegibPhase 35 trials
Gemtuzumab OzogamicinPhase 2ADC1 trial
Gemtuzumab OzogamicinPhase 2ADC1 trial
PF-04449913Phase 21 trial
mitoxantrone + etoposide + gemtuzumab ozogamicinPhase 2ADC1 trial
+15 more programs
Active Trials
NCT01889407Unknown94Est. Jul 2016
NCT05166135Completed589Est. Nov 2022
NCT00161668Completed500
+21 more trials
Astellas
AstellasChina - Shenyang
6 programs
3
1
1
1
gilteritinibPhase 3Small Molecule1 trial
GilteritinibPhase 1/2Small Molecule1 trial
AGS67EPhase 11 trial
ASP1235Phase 11 trial
GilteritinibPhase 1Small Molecule1 trial
+1 more programs
Active Trials
NCT06463639Completed1,213Est. Jun 2024
NCT02610062Terminated23Est. Nov 2017
NCT02864290Terminated43Est. Sep 2020
+3 more trials
Teva
4 programs
1
2
1
1
Arsenic trioxidePhase 31 trial
CEP-701Phase 21 trial
DecitabinePhase 21 trial
CytarabinePhase 1/22 trials
Active Trials
NCT02688140Completed135Est. Jan 2025
NCT02440568Terminated22Est. Nov 2018
NCT00079482Completed224Est. Jan 2010
+2 more trials
Jazz Pharmaceuticals
7
1
6
2
CytarabinePhase 31 trial
DociparstatPhase 3Small Molecule1 trial
Allogeneic Hematopoietic Stem Cell TransplantationPhase 21 trial
CPX-351Phase 21 trial
CPX-351Phase 21 trial
+12 more programs
Active Trials
NCT05169307Completed147Est. Jun 2022
NCT04075747Completed57Est. Sep 2023
NCT04038437Completed35Est. Sep 2022
+13 more trials
DS
10 programs
3
4
2
1
ChemotherapyPhase 31 trial
QuizartinibPhase 2Small Molecule1 trial
Quizartinib High DosePhase 21 trial
DecitabinePhase 1/21 trial
PLX3397Phase 1/21 trial
+5 more programs
Active Trials
NCT03671564Completed14Est. Sep 2019
NCT03647202Completed18Est. Sep 2018
NCT02319369Terminated74Est. Aug 2020
+9 more trials
Astex Pharmaceuticals
Astex PharmaceuticalsUK - Cambridge
9 programs
4
3
1
1
guadecitabinePhase 31 trial
GuadecitabinePhase 21 trial
AT9283Phase 1/21 trial
CDA Inhibitor E7727/Decitabine Combination Agent ASTX727Phase 1/21 trial
SNDX-5613Phase 1/21 trial
+4 more programs
Active Trials
NCT04155580TerminatedEst. Jan 2022
NCT06191978RecruitingEst. Dec 2028
NCT04637009TerminatedEst. Feb 2023
+5 more trials
GS
6 programs
2
1
3
MagrolimabPhase 3Monoclonal Antibody1 trial
MagrolimabPhase 3Monoclonal Antibody
MagrolimabPhase 3Monoclonal Antibody1 trial
EntospletinibPhase 1/2Small Molecule1 trial
CyclophosphamidePhase 13 trials
+1 more programs
Active Trials
NCT06413498Recruiting450Est. Jul 2031
NCT04789408Terminated15Est. May 2024
NCT03139370Terminated16Est. Jun 2023
+4 more trials
E
6 programs
2
3
1
Cytarabine or Supportive CarePhase 31 trial
ClofarabinePhase 21 trial
DecitabinePhase 21 trial
E7820Phase 21 trial
DecitabinePhase 11 trial
+1 more programs
Active Trials
NCT01149408Completed3Est. Sep 2014
NCT00538876Completed30Est. Dec 2009
NCT00778375Completed122Est. Jan 2015
+3 more trials
Sellas Life Sciences Group
1
1
Galinpepimut-SPhase 31 trial
Galinpepimut-SPhase 21 trial
Galinpepimut-SN/A1 trial
Active Trials
NCT05593185Available
NCT01266083CompletedEst. Sep 2016
NCT04229979Active Not RecruitingEst. Dec 2026
H
3 programs
2
1
HMPL-306 RegimenPhase 31 trial
HMPL-306Phase 11 trial
HMPL-523Phase 11 trial
Active Trials
NCT04272957Unknown75Est. Dec 2022
NCT03483948Terminated7Est. Sep 2019
NCT06387069Recruiting316Est. Sep 2029
Heidelberg Pharma
1
1
Gemtuzumab Ozogamicin 147Phase 3ADC1 trial
PalbociclibPhase 1/2Small Molecule1 trial
Active Trials
NCT02310243Unknown50Est. Jul 2019
NCT04093505Terminated28Est. Jun 2022
One Biosciences
1
Vidaza 100 milligramPhase 31 trial
Active Trials
NCT05188326CompletedEst. Sep 2021
CP
1 program
1
gemtuzumab ozogamycinPhase 31 trial
Active Trials
NCT00860639Completed327Est. Sep 2016
AstraZeneca
4 programs
3
1
AZD1152Phase 2/31 trial
AZD1152Phase 11 trial
AZD1208Phase 11 trial
CLL1 and CD38 Dual-Target CAR-T Cell InjectionPhase 1Cell Therapy1 trial
Active Trials
NCT00926731Completed4Est. May 2011
NCT01489722Terminated55Est. May 2014
NCT06880354Recruiting37Est. Mar 2028
+1 more trials
BP
Basilea PharmaceuticaSwitzerland - Allschwil
2 programs
1
1
IsavuconazolePhase 2/3Small Molecule1 trial
APX001 with Standard of Care anti-fungal agentPhase 11 trial
Active Trials
NCT03333005CompletedEst. Oct 2018
NCT00413439CompletedEst. Jun 2007
AbbVie
10 programs
6
3
AzacitidinePhase 21 trial
CytarabinePhase 21 trial
VenetoclaxPhase 21 trial
ABBV-787Phase 11 trial
Biospecimen CollectionPhase 11 trial
+5 more programs
Active Trials
NCT06439966No Longer Available
NCT06068868Terminated36Est. Feb 2025
NCT06034470Recruiting30Est. Dec 2029
+6 more trials
Taiho Oncology
Taiho OncologyNJ - Princeton
6 programs
4
1
1
ASTX727Phase 21 trial
Decitabine and CedazuridinePhase 1/21 trial
ASTX727Phase 11 trial
ASTX727Phase 11 trial
Decitabine and CedazuridinePhase 1
+1 more programs
Active Trials
NCT04953897RecruitingEst. Dec 2026
NCT04953910RecruitingEst. Dec 2026
NCT04282668TerminatedEst. Feb 2024
+2 more trials
Novartis
NovartisBASEL, Switzerland
6 programs
2
1
3
MBG453Phase 21 trial
MidostaurinPhase 21 trial
midostaurinPhase 25 trials
ItraconazolePhase 1/2Small Molecule1 trial
RAD001Phase 15 trials
+1 more programs
Active Trials
NCT01490749Completed17Est. Feb 2019
NCT01283334Completed20Est. Nov 2014
NCT01324492Completed16Est. Jun 2014
+11 more trials
Stemline Therapeutics
5 programs
2
1
2
TagraxofuspPhase 21 trial
TagraxofuspPhase 21 trial
Tagraxofusp-erzsPhase 1/21 trial
AzacitidinePhase 11 trial
AzacitidinePhase 11 trial
Active Trials
NCT03113643Recruiting72Est. May 2027
NCT05720988Withdrawn0Est. Aug 2026
NCT02270463Terminated16Est. Dec 2019
+2 more trials
Knight Therapeutics
3
1
Biospecimen CollectionPhase 21 trial
AzacitidinePhase 11 trial
Biospecimen CollectionPhase 11 trial
Decitabine and CedazuridinePhase 11 trial
Active Trials
NCT06357182Recruiting24Est. May 2026
NCT04659616Recruiting32Est. Dec 2026
NCT05396859Active Not Recruiting13Est. Jun 2026
+1 more trials
Sanofi
4 programs
1
1
2
ClofarabinePhase 21 trial
ClofarabinePhase 21 trial
SAR443579Phase 1/22 trials
clofarabinePhase 15 trials
Active Trials
NCT02425904Active Not Recruiting25Est. Jul 2026
NCT01534702Unknown60Est. Sep 2015
NCT01471444Completed256Est. Dec 2020
+6 more trials
Bristol Myers Squibb
3 programs
1
1
oral azacitidinePhase 21 trial
BMS-986497Phase 11 trial
Oral azacitidineN/A1 trial
Active Trials
NCT06073769Recruiting154Est. Jul 2027
NCT06419634Recruiting105Est. Sep 2030
NCT06180863Withdrawn0Est. Apr 2029
Amgen
3 programs
2
1
azacitidinePhase 24 trials
EmerfetamabPhase 1Monoclonal Antibody1 trial
VenetoclaxPhase 11 trial
Active Trials
NCT03224819Terminated46Est. Dec 2020
NCT03797261Terminated9Est. Dec 2019
NCT05209152Terminated7Est. Dec 2023
+3 more trials
Kura Oncology
3 programs
2
1
Biospecimen CollectionPhase 21 trial
VenetoclaxPhase 11 trial
ZiftomenibPhase 1Small Molecule1 trial
Active Trials
NCT06448013Recruiting22Est. Dec 2030
NCT05735184Recruiting420Est. Apr 2030
NCT06930352Not Yet Recruiting70Est. Dec 2027
BioLineRx
BioLineRxIsrael - Modi’in
3 programs
1
2
Ara-CPhase 21 trial
CytarabinePhase 21 trial
BL-8040Phase 1/2
Active Trials
NCT01838395CompletedEst. Jul 2023
Aptose Biosciences
Aptose BiosciencesCA - San Diego
2 programs
1
1
GTI-2040Phase 21 trial
CG-806Phase 11 trial
Active Trials
NCT04477291TerminatedEst. Apr 2024
NCT00565058CompletedEst. Feb 2010
ImmunityBio
ImmunityBioSAN DIEGO, CA
2 programs
1
1
Graft cell infusionPhase 21 trial
Neukoplast™Phase 11 trial
Active Trials
NCT00900809Completed7Est. Jun 2015
NCT02782546Active Not RecruitingEst. Feb 2028
Rigel Pharmaceuticals
1
1
OlutasidenibPhase 2Small Molecule1 trial
Olutasidenib Investigational Agent AdministrationPhase 11 trial
Active Trials
NCT07130695RecruitingEst. Oct 2030
NCT06782542RecruitingEst. May 2029
Catalyst Pharmaceuticals
1
DecitabinePhase 21 trial
Active Trials
NCT05796570RecruitingEst. Sep 2029
J&
1
ZARNESTRA, tipifarnib, R115777Phase 22 trials
Active Trials
NCT00050154Completed82Est. May 2006
NCT00048503Completed88Est. Nov 2005

+37 more companies

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
2030
2031
NovartisRAD001
Gilead SciencesCyclophosphamide
HutchmedHMPL-306 Regimen
Gilead SciencesMagrolimab
Gilead SciencesMagrolimab
PfizerGlasdegib
Jazz PharmaceuticalsDociparstat
Heidelberg PharmaGemtuzumab Ozogamicin 147
Sellas Life Sciences GroupGalinpepimut-S
Jazz PharmaceuticalsCytarabine
Novartismidostaurin
Astellasgilteritinib
Astex Pharmaceuticalsguadecitabine
Daiichi SankyoChemotherapy
TevaCytarabine

Showing 15 of 50 trials with date data

Clinical Trials (50)

Total enrollment: 7,163 patients across 50 trials

A Trial of Everolimis in Patients With Advanced Renal Cell Carcinoma.

Start: Nov 2009Est. completion: Jul 2017143 patients
Phase 4Completed

A Study Comparing Anitocabtagene Autoleucel to Standard of Care Therapy in Participants With Relapsed/ Refractory Multiple Myeloma

Start: Aug 2024Est. completion: Jul 2031450 patients
Phase 3Recruiting
NCT06387069HutchmedHMPL-306 Regimen

A Study to Evaluate HMPL-306 in Patients With IDH1or IDH2-mutated Acute Myeloid Leukemia

Start: Apr 2024Est. completion: Sep 2029316 patients
Phase 3Recruiting

Study of Magrolimab Versus Placebo in Combination With Venetoclax and Azacitidine in Participants With Acute Myeloid Leukemia

Start: Jul 2022Est. completion: Apr 2024378 patients
Phase 3Terminated

Study of Magrolimab in Combination With Azacitidine Versus Physician's Choice of Venetoclax in Combination With Azacitidine or Intensive Chemotherapy in Patients With TP53 Mutant Acute Myeloid Leukemia That Have Not Been Treated

Start: Jul 2021Est. completion: Mar 2024258 patients
Phase 3Terminated

Continuation Study of B1371019(NCT03416179) and B1371012(NCT02367456) Evaluating Azacitidine With Or Without Glasdegib In Patients With Previously Untreated AML, MDS or CMML

Start: May 2021Est. completion: Dec 202214 patients
Phase 3Completed

Dociparstat in Combination With Standard Chemotherapy for the Treatment of Acute Myeloid Leukemia

Start: Apr 2021Est. completion: May 20229 patients
Phase 3Terminated
NCT04093505Heidelberg PharmaGemtuzumab Ozogamicin 147

Gemtuzumab Ozogamicin in Induction and Glasdegib in Postremission Therapy in Patients With AML (Acute Myeloid Leukemia)

Start: Apr 2021Est. completion: Jun 202228 patients
Phase 3Terminated

Galinpepimut-S Versus Investigator's Choice of Best Available Therapy for Maintenance in AML CR2/CRp2

Start: Feb 2021Est. completion: Dec 2026
Phase 3Active Not Recruiting

Study of Standard Intensive Chemotherapy Versus Intensive Chemotherapy With CPX-351 in Adult Patients With Newly Diagnosed AML and Intermediate- or Adverse Genetics

Start: Sep 2019Est. completion: Jun 2027882 patients
Phase 3Active Not Recruiting

Study to Assess the Safety and Efficacy of Midostaurin (PKC412) in Combination With Standard Chemotherapy During Induction and Consolidation Followed by 12 Months of Maintenance Monotherapy in Patients With Newly-diagnosed FMS-like Tyrosine 3 (FLT3) Kinase Receptor-mutated Acute Myeloid Leukemia.

Start: Feb 2018Est. completion: Jul 2021301 patients
Phase 3Completed

A Trial of the FMS-like Tyrosine Kinase 3 (FLT3) Inhibitor Gilteritinib Administered as Maintenance Therapy Following Allogeneic Transplant for Patients With FLT3/Internal Tandem Duplication (ITD) Acute Myeloid Leukemia (AML)

Start: Aug 2017Est. completion: May 2023356 patients
Phase 3Completed

Phase 3 Randomized, Open-Label Study of Guadecitabine vs Treatment Choice in Previously Treated Acute Myeloid Leukemia

Start: Mar 2017Est. completion: Jun 2020
Phase 3Completed

Quizartinib With Standard of Care Chemotherapy and as Continuation Therapy in Patients With Newly Diagnosed FLT3-ITD (+) Acute Myeloid Leukemia (AML)

Start: Sep 2016Est. completion: Jun 2023539 patients
Phase 3Completed
NCT02688140TevaCytarabine

Study for Patients With Newly Diagnosed, High-risk Acute Promyelocytic Leukemia

Start: Jun 2016Est. completion: Jan 2025135 patients
Phase 3Completed

Fludarabine-IV Busulfan ± Clofarabine and Allogeneic Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS)

Start: Nov 2011Est. completion: Dec 2020256 patients
Phase 3Completed
NCT05188326One BiosciencesVidaza 100 milligram

Efficacy of 5-Aza for Post-Remission Therapy of Acute Myeloid Leukemia (AML) in Elderly Patients

Start: Nov 2010Est. completion: Sep 2021
Phase 3Completed

Clofarabine Plus Cytarabine Versus Conventional Induction Therapy And A Study Of NK Cell Transplantation In Newly Diagnosed Acute Myeloid Leukemia

Start: Aug 2008Est. completion: Aug 2020324 patients
Phase 3Completed
NCT00860639Chugai Pharmagemtuzumab ozogamycin

Efficacy of Gemtuzumab Ozogamycin for Patients Presenting an Acute Myeloid Leukemia (AML) With Intermediate Risk

Start: Oct 2007Est. completion: Sep 2016327 patients
Phase 3Completed
NCT00513305TevaArsenic trioxide

Cytarabine in Combination With Arsenic Trioxide vs. Cytarabine Alone in Elderly Patients With Acute Myeloid Leukemia

Start: Oct 2007Est. completion: Dec 200967 patients
Phase 3Terminated

A Study of Clofarabine and Cytarabine for Older Patients With Relapsed or Refractory Acute Myelogenous Leukemia (AML)(CLASSIC I)

Start: Aug 2006Est. completion: Jan 2012326 patients
Phase 3Completed
NCT00260832EisaiCytarabine or Supportive Care

Trial of Decitabine in Patients With Acute Myeloid Leukemia

Start: Nov 2005Est. completion: Dec 2010485 patients
Phase 3Completed

Study to Investigate the Efficacy, Safety and Tolerability of AZD1152 Alone and in Combination With Low Dose Cytosine Arabinoside (LDAC)in Acute Myeloid Leukaemia (AML) Patients

Start: Jul 2009Est. completion: Jun 201174 patients
Phase 2/3Completed

Safety, Efficacy and Pharmacokinetics of an Antifungal in Patients Undergoing Chemotherapy

Start: May 2006Est. completion: Jun 2007
Phase 2/3Completed
NCT00037583PfizerGemtuzumab Ozogamicin

Study Evaluating the Safety and Efficacy of Gemtuzumab Ozogamicin in Patients With Acute Myeloid Leukemia

Est. completion: Sep 200369 patients
Phase 2Completed

Olutasidenib, Venetoclax, and Azacitidine in IDH1 Mutated Newly Diagnosed Acute Myeloid Leukemia Patients Eligible for Intensive Induction Chemotherapy

Start: May 2026Est. completion: May 2029
Phase 2Recruiting
NCT06930352Kura OncologyBiospecimen Collection

Ziftomenib for the Treatment of Patients With NPM1 Mutated or KMT2A Rearranged Acute Myeloid Leukemia Not Eligible for Standard Therapy

Start: Apr 2026Est. completion: Dec 202770 patients
Phase 2Not Yet Recruiting
NCT07228273Knight TherapeuticsBiospecimen Collection

Induction and Consolidation With Fludarabine, Cytarabine, Idarubicin, and Venetoclax for the Treatment of Acute Myeloid Leukemia

Start: Dec 2025Est. completion: Aug 2029102 patients
Phase 2Recruiting
NCT06824168Daiichi SankyoQuizartinib High Dose

Evaluation of Two Dose Levels of Quizartinib as Maintenance in FLT3-ITD (+) Acute Myeloid Leukemia Patients in Complete Remission

Start: Jul 2025Est. completion: Jul 2032130 patients
Phase 2Recruiting

A Study of Tagraxofusp in Combination With Venetoclax and Azacitidine in Adults With Untreated CD123+ Acute Myeloid Leukemia Who Cannot Undergo Intensive Chemotherapy

Start: Jan 2025Est. completion: Feb 203083 patients
Phase 2Recruiting

Tagraxofusp and Azacitidine With Venetoclax in Newly Diagnosed Secondary AML After Hypomethylating Agents

Start: May 2024Est. completion: Dec 202753 patients
Phase 2Recruiting

Oral Azacitidine (CC-486) Epigenetic Priming and Maintenance for Adult Acute Myeloid Leukemia (AML) Patients

Start: Nov 2023Est. completion: Apr 20290
Phase 2Withdrawn

A Study of Venetoclax in Combination With Conventional Chemotherapy in Pediatric Patients With Acute Myeloid Leukemia

Start: Jul 2023Est. completion: Mar 203470 patients
Phase 2Suspended
NCT05260528Jazz PharmaceuticalsCytarabine and Idarubicin

CPX-351 vs Intensive Chemotherapy in Patients With de Novo Intermediate or Adverse Risk AML Stratified by Genomics

Start: May 2023Est. completion: Oct 2027210 patients
Phase 2Recruiting

A Pilot Study to Evaluate the Feasibility of Post-Hematopoietic Stem Cell Transplant Prophylaxis With Decitabine Combined With Filgrastim for Children and Young Adults With AML, MDS and Related Myeloid Malignancies

Start: Apr 2023Est. completion: Sep 2029
Phase 2Recruiting

Azacitidine or Decitabine With Venetoclax for Acute Myeloid Leukemia With Prior Hypomethylating Agent Failure

Start: Feb 2022Est. completion: Dec 202520 patients
Phase 2Recruiting

A Study of E7820 in People With Bone Marrow (Myeloid) Cancers

Start: Aug 2021Est. completion: Jun 202512 patients
Phase 2Completed
NCT04526288Jazz PharmaceuticalsAllogeneic Hematopoietic Stem Cell Transplantation

CPX-351 Versus Immediate Stem Cell Transplantation for the Treatment of High-Grade Myeloid Cancers With Measurable Residual Disease

Start: Aug 2021Est. completion: Aug 20231 patients
Phase 2Terminated

Venetoclax + Azacitidine vs. Induction Chemotherapy in AML

Start: May 2021Est. completion: Jan 2028172 patients
Phase 2Recruiting

A Study of MBG453 in Combination With Azacitidine and Venetoclax in AML Patients Unfit for Chemotherapy

Start: Sep 2020Est. completion: Oct 202490 patients
Phase 2Terminated
NCT04195945Jazz PharmaceuticalsLiposome-encapsulated Daunorubicin-Cytarabine

CPX-351 or CLAG-M Regimen for the Treatment of Acute Myeloid Leukemia or Other High-Grade Myeloid Neoplasms in Medically Less-Fit Patients

Start: Mar 2020Est. completion: Dec 202760 patients
Phase 2Active Not Recruiting

CPX-351 and Glasdegib for Newly Diagnosed Acute Myelogenous Leukemia With MDS Related Changes or Therapy-related Acute Myeloid Leukemia

Start: Feb 2020Est. completion: Jun 202730 patients
Phase 2Active Not Recruiting
NCT03374332PfizerGemtuzumab Ozogamicin

Fractionated Gemtuzumab Ozogamicin Followed by Non-engraftment Donor Leukocyte Infusions for Relapsed/Refractory Acute Myeloid Leukemia

Start: Dec 2019Est. completion: Sep 202411 patients
Phase 2Active Not Recruiting

GLAD-AML - Glasdegib (Pf-04449913) With Two Standard Decitabine Regimens for Older Patients With Poor-risk Acute Myeloid Leukemia

Start: Dec 2019Est. completion: Jun 20201 patients
Phase 2Terminated

A Study for Participants Who Participated in Prior Clinical Studies of ASTX727 (Standard Dose)

Start: Sep 2019Est. completion: Dec 2027
Phase 2Enrolling By Invitation

Trial to Compare Efficacy and Safety of Chemotherapy/Quizartinib vs Chemotherapy/Placebo in Adults FMS-like Tyrosine Kinase 3 (FLT3) Wild-type Acute Myeloid Leukemia (AML)

Start: Sep 2019Est. completion: Jan 2025273 patients
Phase 2Completed

A Global Study of Midostaurin in Combination With Chemotherapy to Evaluate Safety, Efficacy and Pharmacokinetics in Newly Diagnosed Pediatric Patients With FLT3 Mutated AML

Start: Mar 2019Est. completion: May 202922 patients
Phase 2Active Not Recruiting
NCT03839446Pfizermitoxantrone + etoposide + gemtuzumab ozogamicin

Phase II Study of the Combination of Mitoxantrone, Etoposide and Gemtuzumab Ozogamicin (MEGO) for Patients With Acute Myeloid Leukemia Refractory to Initial Standard Induction Therapy

Start: Feb 2019Est. completion: Dec 202416 patients
Phase 2Completed

iCare4: Genomic Signatures With Midostaurin in Acute Myeloid Leukemia (UF-HEM-004)

Start: Nov 2018Est. completion: Jan 20220
Phase 2Withdrawn

Guadecitabine Extension Study

Start: Jul 2018Est. completion: Oct 2021
Phase 2Terminated

Related Jobs in Oncology

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

16 late-stage (Phase 3) programs — potential near-term approvals
11 actively recruiting trials targeting 7,163 patients
30 companies competing in this space