Unspecified Adult Solid Tumor, Protocol Specific

Oncology
14
Pipeline Programs
12
Companies
18
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
11
1
2
0
0
0
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Small Molecule
3100%
+ 11 programs with unclassified modality

Competitive Landscape

11 companies ranked by most advanced pipeline stage

Alliance Pharmaceuticals
2 programs
1
1
paclitaxelPhase 25 trials
interleukin 2Phase 11 trial
Active Trials
NCT00002994Completed355Est. Apr 2002
NCT02967133Terminated7Est. Jan 2018
NCT00005646Completed36Est. Feb 2008
+3 more trials
Bayer
BayerLEVERKUSEN, Germany
1 program
1
SorafenibPhase 2Small Molecule1 trial
Active Trials
NCT00810394Completed50Est. Mar 2012
Nektar Therapeutics
Nektar TherapeuticsSAN FRANCISCO, CA
1 program
1
NKTR-214Phase 1/21 trial
Active Trials
NCT02869295CompletedEst. Oct 2018
Sanofi
SanofiPARIS, France
2 programs
2
apominePhase 12 trials
intoplicinePhase 11 trial
Active Trials
NCT00004049Completed36
NCT00003822Completed30
NCT00003713Completed35
City Therapeutics
City TherapeuticsMA - Cambridge
2 programs
2
celecoxibPhase 1Small Molecule1 trial
celecoxibPhase 1Small Molecule1 trial
Active Trials
NCT00551005CompletedEst. Feb 2012
NCT00551889CompletedEst. Feb 2012
E
EisaiChina - Liaoning
1 program
1
E7389Phase 11 trial
Active Trials
NCT01418677Completed19Est. May 2015
Astex Pharmaceuticals
Astex PharmaceuticalsUK - Cambridge
1 program
1
Oral EtoposidePhase 11 trial
Active Trials
NCT00006047CompletedEst. Feb 2003
Abbott
AbbottABBOTT PARK, IL
1 program
1
gemcitabine hydrochloridePhase 11 trial
Active Trials
NCT00217477Completed34Est. Sep 2014
Kazia Therapeutics
Kazia TherapeuticsAustralia - Sydney
1 program
1
idronoxilPhase 11 trial
Active Trials
NCT00022295CompletedEst. Oct 2007
Genentech
GenentechCA - Oceanside
1 program
1
ixabepilonePhase 1
Novartis
NovartisBASEL, Switzerland
1 program
1
warfarinPhase 11 trial
Active Trials
NCT00091299Completed24Est. Aug 2012

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Alliance Pharmaceuticalspaclitaxel
Alliance Pharmaceuticalspaclitaxel
BayerSorafenib
Alliance Pharmaceuticalspaclitaxel
Alliance Pharmaceuticalspaclitaxel
Alliance Pharmaceuticalspaclitaxel
Nektar TherapeuticsNKTR-214
EisaiE7389
Abbottgemcitabine hydrochloride
Novartiswarfarin
City Therapeuticscelecoxib
City Therapeuticscelecoxib
Kazia Therapeuticsidronoxil
Astex PharmaceuticalsOral Etoposide
Sanofiapomine

Showing 15 of 18 trials with date data

Clinical Trials (18)

Total enrollment: 862 patients across 18 trials

NCT00003092Alliance Pharmaceuticalspaclitaxel

Paclitaxel in Treating Older Patients With Solid Tumors

Start: Sep 1997Est. completion: Jun 2006120 patients
Phase 3Completed
NCT02967133Alliance Pharmaceuticalspaclitaxel

A Study of Nivolumab +/- Nab-paclitaxel in Non-small Cell Lung Cancer

Start: Dec 2016Est. completion: Jan 20187 patients
Phase 2Terminated
NCT00810394BayerSorafenib

Sorafenib in Treating Patients With Advanced Malignant Solid Tumors

Start: Dec 2008Est. completion: Mar 201250 patients
Phase 2Completed
NCT00005646Alliance Pharmaceuticalspaclitaxel

Paclitaxel in Treating Patients With Extensive-Stage Small Cell Lung Cancer

Start: Apr 2000Est. completion: Feb 200836 patients
Phase 2Completed
NCT00003281Alliance Pharmaceuticalspaclitaxel

Topotecan and Paclitaxel in Treating Patients With Recurrent or Refractory Small Cell Lung Cancer

Start: Apr 1998Est. completion: Mar 200684 patients
Phase 2Completed
NCT00003130Alliance Pharmaceuticalspaclitaxel

Paclitaxel in Treating Women With Recurrent Solid Tumors

Start: Nov 1997Est. completion: Jan 200632 patients
Phase 2Completed
NCT02869295Nektar TherapeuticsNKTR-214

A Phase 1/2 Multicenter Dose Escalation and Expansion Study Of NKTR-214 In Subjects With Locally Advanced Or Metastatic Solid Tumors

Start: Dec 2015Est. completion: Oct 2018
Phase 1/2Completed
NCT01418677EisaiE7389

An Open-Label Study to Assess the Pharmacokinetics and Safety of HALAVEN in Subjects With Cancer Who Also Have Impaired Renal Function

Start: Oct 2011Est. completion: May 201519 patients
Phase 1Completed
NCT00217477Abbottgemcitabine hydrochloride

Paricalcitol and Gemcitabine in Treating Patients With Advanced Cancer

Start: Aug 2004Est. completion: Sep 201434 patients
Phase 1Completed
NCT00091299Novartiswarfarin

Warfarin and Vatalanib in Treating Patients With Advanced Solid Tumors

Start: May 2004Est. completion: Aug 201224 patients
Phase 1Completed
NCT00551005City Therapeuticscelecoxib

Etoposide and Celecoxib in Patients With Advanced Cancer

Start: Dec 2001Est. completion: Feb 2012
Phase 1Completed
NCT00551889City Therapeuticscelecoxib

Cyclophosphamide and Celecoxib in Treating Patients With Advanced Cancer

Start: Sep 2001Est. completion: Feb 2012
Phase 1Completed
NCT00022295Kazia Therapeuticsidronoxil

Phenoxodiol in Treating Patients With Refractory Solid Tumors

Start: Aug 2001Est. completion: Oct 2007
Phase 1Completed
NCT00006047Astex PharmaceuticalsOral Etoposide

Combination Therapy With Oral 9-Nitrocamptothecin & Oral Etoposide

Start: Jun 2000Est. completion: Feb 2003
Phase 1Completed
NCT00004049Sanofiapomine

SR-45023A in Treating Patients With Locally Advanced or Metastatic Solid Tumors

Start: Apr 199936 patients
Phase 1Completed
NCT00003822Sanofiapomine

SR-45023A in Treating Patients With Advanced Solid Tumors

Start: Aug 199830 patients
Phase 1Completed
NCT00003713Sanofiintoplicine

Chemotherapy in Treating Patients With Advanced or Metastatic Solid Tumors

Start: Aug 199735 patients
Phase 1Completed
NCT00002994Alliance Pharmaceuticalsinterleukin 2

Interleukin-2 Plus Monoclonal Antibody Therapy in Treating Patients With Solid Tumors

Start: Jul 1997Est. completion: Apr 2002355 patients
Phase 1Completed

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Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

12 companies competing in this space

Related Indications

Breast Cancer(530)Non-small Cell Lung Cancer(373)Prostate Cancer(371)Multiple Myeloma(244)Advanced Solid Tumors(221)Acute Myeloid Leukemia(204)Cancer(187)Neoplasms(173)Colorectal Cancer(166)Advanced Solid Tumor(165)