City Therapeutics

Focus: City Therapeutics is a Cambridge-based biotech company focused on RNAi and gene therapies, operating at public-stage scale with 5,000+ employees since its 2018 founding.

Gene Therapy

Profile data last refreshed 9h ago · AI intelligence enriched 2w ago

Funding Stage

PUBLIC

Employees

5000+

Open Jobs

5+1 this month

Stable — net +1 jobs in 30d

2 added, 1 removed. Backfill posture.

Should You Work at City Therapeutics?

AI assessment

City Therapeutics offers biotech scale and modality focus, but pipeline opacity and minimal hiring activity warrant deep due diligence before committing.

Why Work Here

Established public company with 5,000+ employee base provides stability and career infrastructure rare in early-stage biotech.
Gene therapy and RNAi focus positions you in high-growth therapeutic modalities with significant unmet medical need.

Data completeness

2/9 — Limited

Company HealthSolid

Pipeline

Early-stage

50 total

LOE Risk

Protected

No near-term cliffs

Hiring

Stable

Automated analysis based on publicly available data (FDA, SEC, ClinicalTrials.gov). May be incomplete or delayed. This score does not reflect insider knowledge and should not be used as the sole basis for investment or employment decisions.

Pipeline & Clinical Trials

Vitls Tego Device

Vital Signs

N/A

Clinical Trials (1)

NCT05245747Vitls Feasibility Physiologic Monitoring

N/A

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Data Sources

Drug label: DailyMed / FDA
Clinical trials: ClinicalTrials.gov
Patent data: FDA Orange Book
Spending data: CMS Medicare

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.

Cambridge headquarters offers access to world-class research ecosystem and pharma talent marketplace.

Watch Out For

Pipeline data quality is severely compromised—roster contains predominantly clinical trial metadata (supportive care, surgical techniques, diet counseling) rather than proprietary therapeutics, suggesting data integrity or portfolio clarity issues.
Only 4 active job openings across entire organization signals minimal hiring momentum and limited near-term career mobility.

Generated by Claude from City Therapeutics's SEC filings, pipeline programs, hiring velocity, FDA actions, and WARN data. Inference, not editorial — verify before quoting.

Optimizing Post-Thoracotomy Pain Management: Comparing Erector Spinae vs. Paravertebral Block in Tho

Lung Diseases

N/A

Clinical Trials (1)

NCT06964698Optimizing Post-Thoracotomy Pain Management: Comparing Erector Spinae vs. Paravertebral Block in Thoracotomy Patients

N/A

Comparison of Short- and Long-term Outcomes Between Robotic and Laparoscopic Hemicolectomy of Right

Robotic Surgical Procedures

N/A

Mopati

HIV

N/A

Clinical Trials (1)

NCT04796610Mopati: A Pilot Hiv Treatment Partner Intervention In Botswana

N/A

Standard open tension-free inguinal hernia repair with mesh

Inguinal Hernias

N/A

Clinical Trials (1)

NCT01922674Inguinal Hernia Management: Watchful Waiting vs. Tension-Free Open Repair

N/A

No intervention

Parkinsonian Disorders

N/A

Trauma Exposure and Childhood Trauma in Temporomandibular Joint Disorders

Temporomandibular Disorder

N/A

Clinical Trials (1)

NCT07292103Trauma Exposure and Childhood Trauma in Temporomandibular Joint Disorders

N/A

Using advanced platelet-rich fibrin

Chronic Apical Periodontitis

N/A

Clinical Trials (1)

NCT07192289Using Platelet-rich Fibrin in Regenerative Endodontic Treatment in Mature Permanent Teeth

N/A

Uroflowmetry with URI Calculation

Urethral Stricture

N/A

Clinical Trials (1)

NCT07403786Urethral Resistive Index (URI): A New Parameter for Diagnosing Urethral Obstruction

N/A

Surgery method

Prostate Hyperplasia

N/A

Clinical Trials (1)

NCT05108662Inflammatory Markers: HOLEP Versus TURP

N/A

Biospecimen Collection

Accelerated Phase CML, BCR-ABL1 Positive

N/A

Clinical Trials (1)

NCT04666025SARS-CoV-2 Donor-Recipient Immunity Transfer

N/A

OLT maneuver

Healthy Volunteers

N/A

Clinical Trials (1)

NCT00742989Effect of Osteopathic Lymphatic Treatment on Plasma Volume, Protein Concentration and Albumin Concentration.

N/A

Care of premature infants

Morbidity;Infant

N/A

Clinical Trials (1)

NCT06543524Survival and nEonatal outComes of veRy Low Birth wEight Infants in Türkiye: Turkish Neonatal Society SECRETS-TR Study

N/A

Our Emergency Fasciotomy and Amputation Experiences

Amputation

N/A

Clinical Trials (1)

NCT06764446Our Emergency Fasciotomy and Amputation Experiences

N/A

Relations Between Residual Renal Function and Oxidative and Carbonyl Stress in Peritoneal Dialysis P

Chronic Renal Failure

N/A

Clinical Trials (1)

NCT00692068Relations Between Residual Renal Function and Oxidative and Carbonyl Stress in Peritoneal Dialysis Patients

N/A

Ultrasound measurements

Fetal Growth Retardation

N/A

Clinical Trials (1)

NCT06215690Evaluation of Anterior Middle Brain Structures With Cerebrovascular Flow in Fetuses With Fetal Growth Restriction

N/A

Application and demonstration of endoscope-assisted low-temperature plasma radiofrequency ablation resection of tonsils

Tonsil Disease

N/A

Clinical Trials (1)

NCT06983860Application and Demonstration of Endoscope-assisted Low-temperature Plasma Radiofrequency Ablation Resection of Tonsils

N/A

White bread

Healthy Participants

N/A

Clinical Trials (1)

NCT07158762Blood Glucose Levels After Bread Consumption Between Participants With Normal Weight and Overweight/Obesity

N/A

Erector Spinae Plane Block

Kolon Kanseri

N/A

Clinical Trials (1)

NCT07297433Erector Spinae Plane Block in Laparoscopic Colorectal Cancer Surgery

N/A

Estrogen Levels and Postoperative Recovery in IVF Patients

In Vitro Fertilization

N/A

Clinical Trials (1)

NCT06925633Estrogen Levels and Postoperative Recovery in IVF Patients

N/A

No intervention

Pilonidal Sinus Disorder

N/A

Clinical Trials (1)

NCT07370714Factors Affecting Wound Dehiscence in Pilonidal Sinus Surgery (ORIPIS)

N/A

E-CUBE i7 ultrasound system

Intracranial Pressure Increase

N/A

Clinical Trials (1)

NCT05668208Do Extraperitoneal Laparoscopic Surgeries Increase Intracranial Pressure?

N/A

Chinese Research Group of Gallbladder Cancer

Gallbladder Neoplasms

N/A

Education

Nursing Education

N/A

Clinical Trials (1)

NCT06388798Evaluation of the Effectiveness of Psychoeducational Training Given to Nurses Working in a Psychiatric Clinic

N/A

FVIII Concentrates

Severe Hemophilia A

N/A

Predictors of Spinal Anesthesia-Induced Hypotension in Hypertensive Patients

Spinal Anesthesia-Induced Hypotension

N/A

Clinical Trials (1)

NCT06749184Predictors of Spinal Anesthesia-Induced Hypotension in Hypertensive Patients

N/A

IVA group

The Injection Burden

N/A

No Intervention

Gastrointestinal Cancers

N/A

Clinical Trials (1)

NCT07272538Predicting Chemotherapy Toxicity Using FRAIL and FIND in Older Adults With Gastrointestinal Cancers

N/A

Babysparks Application

Development, Child

N/A

Clinical Trials (1)

NCT03867903BabySparks Developmental Application Pilot Study

N/A

Tissue culture collection

Wound Infection Bacterial

N/A

Clinical Trials (1)

NCT07325786Percutaneous Wound Sampling With Analysis in Blood Culture (PERKA-B) Method

N/A

Schoolyard reconstruction

Physical Inactivity

N/A

Clinical Trials (1)

NCT05865782Reconstructing Schoolyards With Greenery to Increase Schoolchildren's Physical Activity and Mitigate Climate Changes

N/A

Exercise Intervention

Adult Liver Carcinoma

N/A

Clinical Trials (1)

NCT03267524Walking for Recovery From Surgery in Improving Quality of Life in Older Adults With Lung or Gastrointestinal Cancer and Their Family Caregivers

N/A

Evaluation of Difficult Airway With Ultrasound

Adenotonsillectomy Surgery

N/A

Clinical Trials (1)

NCT07057661Evaluation of Difficult Airway With Ultrasound

N/A

Magnetic Mini-Mover Procedure

Pectus Excavatum

N/A

Clinical Trials (1)

NCT01327274Multicenter Trial of Magnetic Mini-Mover for Pectus Excavatum

N/A

EEG-Guided Sedation in ERCP Procedures

Anesthesia

N/A

Clinical Trials (1)

NCT06866886EEG-Guided Sedation in ERCP Procedures

N/A

TIVA

Cardiac Anesthesia

N/A

Clinical Trials (1)

NCT05320341TIVA Versus Inhalational Anesthesia and Tissue Oxygenation in Cardiac Surgery

N/A

normal colorectal tissues

Metastasis

N/A

Clinical Trials (1)

NCT02917707Integrative Analysis of CRC Liver Metastasis

N/A

Triage Assessment and NEWS-score as Risk Predictor in Older Frailty Adults in the ED

Frailty

N/A

Clinical Trials (1)

NCT03783234Triage Assessment and NEWS-score as Risk Predictor in Older Frailty Adults in the ED

N/A

Comfort Care Bundle

ICU

N/A

Clinical Trials (1)

NCT07366021Comfort Care Bundle

N/A

control group; Patients who received physiological saline

Analgesia

N/A

Clinical Trials (1)

NCT06386575Suprainguinal Fascia Iliaca Block in Knee Arthroplasty

N/A

Understanding Reproductive Health for Ladeez

HIV

N/A

Clinical Trials (1)

NCT02733692Culturally Congruent HIV Risk Reduction App for Young Women, an Acceptability & Pilot Evaluation

N/A

supine position

The Effect of Cuff Pressure on Postoperative Dysphagia

N/A

Clinical Trials (1)

NCT05712135Investigation of Endotracheal Cuff Pressure Changes According to Different Positions in Neurosurgery Cases

N/A

Minimally Invasive Cardiac Surgery

Heart Valvular Disease

N/A

Clinical Trials (1)

NCT06299735Comparison of Airway Management With Bronchial Blocker and Double-Lumen Tube in Single-Lung Ventilation

N/A

Ultrasonic Device

Impacted Mandibular Third Molar

N/A

Clinical Trials (1)

NCT07196904Ultrasonic vs Rotary Instruments in Impacted Mandibular Third Molar Surgery: Clinical and Salivary CRP Outcomes

N/A

Bilateral Oblique Subcostal Transversus Abdominis Plane Block

Mechanical Power

N/A

Clinical Trials (1)

NCT06202040The Effect of Bilateral Rectus Sheath and Oblique Subcostal Transversus Abdominis Plane Block on Mechanical Power

N/A

fetal lung elastography measurement

Preterm Labor

N/A

Clinical Trials (1)

NCT06168149The Relationship of Fetal Lung Elastography Values With the Development of Respiratory Distress in Cases of Preterm Labor

N/A

Awareness survey

Endoscopy

N/A

Clinical Trials (1)

NCT05032443Anesthesia Awareness in Pediatric Gastrointestinal Endoscopy Nurses

N/A

ESTEEM

HIV Infections

N/A

Clinical Trials (1)

NCT02448186Intervention Development for Social Stress, Mental Health, and HIV Risk MSM

N/A

low-flow anesthesia

Oncology

N/A

Clinical Trials (1)

NCT06430593Evaluation of Low Flow and Normal Flow Anesthesia Management in Robotic Assisted Laparoscopic Surgeries

N/A

Interview Prep Quick Facts

Founded: 2018

Portfolio: 51 clinical trials

Top TAs: Oncology, Neurology, Infectious Diseases

Open Roles: 5 active jobs

Therapeutic Area Focus

Oncology

3 pipeline

Neurology

2 pipeline

Infectious Diseases

1 pipeline

Marketed

Pipeline

Hiring Trend

Stable

Open Roles

Added

-0

Filled/Removed

Based on last 4 crawl cycles

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City Therapeutics

Should You Work at City Therapeutics?

Why Work Here

Pipeline & Clinical Trials

Watch Out For

Open Jobs (5)

Sr. Clinical Trial Manager

Senior Director, Clinical Operations

Senior Scientist, CMC, Quality Control

Senior/Principal Scientist, CMC Process Development and Manufacturing

Join the RNAi revolution!

Hiring Trend