Refractory Solid Tumors

Oncology
3
Pipeline Programs
4
Companies
4
Clinical Trials
1 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
2
1
0
0
0
0
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Small Molecule
1100%
+ 3 programs with unclassified modality

Competitive Landscape

4 companies ranked by most advanced pipeline stage

PEEL Therapeutics
PEEL TherapeuticsUT - Salt Lake City
1 program
1
PEEL-224Phase 1/21 trial
Active Trials
NCT06721689RecruitingEst. Apr 2031
AstraZeneca
AstraZenecaCAMBRIDGE, United Kingdom
1 program
1
AZD2461Phase 11 trial
Active Trials
NCT01247168Completed75Est. May 2011
E
EisaiChina - Liaoning
1 program
1
LenvatinibPhase 1Small Molecule1 trial
Active Trials
NCT01525394Completed52
VP
1 program
AVN944N/A1 trial
Active Trials
NCT00923728Withdrawn0Est. Mar 2010

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
2030
2031
PEEL TherapeuticsPEEL-224
EisaiLenvatinib
AstraZenecaAZD2461
Vertex PharmaceuticalsAVN944

Clinical Trials (4)

Total enrollment: 127 patients across 4 trials

NCT06721689PEEL TherapeuticsPEEL-224

PEEL-224, Vincristine and Temozolomide in Pediatric Solid Tumors

Start: Mar 2025Est. completion: Apr 2031
Phase 1/2Recruiting
NCT01525394EisaiLenvatinib

A Double-Blind Study in Healthy Volunteers to Assess the Effect of E7080 on the QTc Interval

Start: Dec 201052 patients
Phase 1Completed
NCT01247168AstraZenecaAZD2461

An Open-Label, Dose-Escalation Study of AZD2461

Start: Nov 2010Est. completion: May 201175 patients
Phase 1Completed
NCT00923728Vertex PharmaceuticalsAVN944

A Phase I Trial of AVN944, an IMPDH Inhibitor, in Adults With Advanced Stage Solid Tumors

Start: Apr 2009Est. completion: Mar 20100
N/AWithdrawn

Related Jobs in Oncology

Senior Research Associate, Immuno-Oncology

SystImmune
2h ago
$60K - $85K/yr

Research Associate I/II, Immuno-Oncology

SystImmune
2h ago

Office Administrator

SystImmune
2h ago
$60K - $80K/yr

Scientist/Sr Scientist

TwoStep Therapeutics
San Carlos
3h ago

Senior Medical Project Manager (m/f/d)

Mindpeak
Hamburg
3h ago

Working Student Active Sourcing Support (m/f/d)

Mindpeak
Hamburg
3h ago

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

1 actively recruiting trials targeting 127 patients
4 companies competing in this space

Related Indications

Breast Cancer(530)Non-small Cell Lung Cancer(373)Prostate Cancer(371)Multiple Myeloma(244)Advanced Solid Tumors(221)Acute Myeloid Leukemia(204)Cancer(187)Neoplasms(173)Colorectal Cancer(166)Advanced Solid Tumor(165)