Lung Non-Small Cell Carcinoma

Oncology
4
Pipeline Programs
6
Companies
21
Clinical Trials
1 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
1
2
0
0
0
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Vaccine
1100%
+ 4 programs with unclassified modality

Competitive Landscape

5 companies ranked by most advanced pipeline stage

City Therapeutics
City TherapeuticsMA - Cambridge
1 program
1
AdagrasibPhase 21 trial
Active Trials
NCT07288034Not Yet RecruitingEst. Sep 2028
Alliance Pharmaceuticals
1 program
1
ChemotherapyPhase 25 trials
Active Trials
NCT01473290Withdrawn0
NCT07293247Not Yet Recruiting164Est. Mar 2032
NCT04062708Active Not Recruiting38Est. Jul 2026
+2 more trials
Varian Medical Systems
1 program
1
Biospecimen CollectionPhase 1/21 trial
Active Trials
NCT05501665RecruitingEst. Feb 2027
M&
Merck & Co.RAHWAY, NJ
1 program
1
Autologous Dendritic Cell-Adenovirus CCL21 VaccinePhase 1Vaccine1 trial
Active Trials
NCT03546361Active Not Recruiting24Est. Jan 2027
Knight Therapeutics
Knight TherapeuticsQC - Montréal
1 program
Best PracticeN/A1 trial
Active Trials
NCT04946279Active Not Recruiting98Est. Dec 2026

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
2030
2031
Alliance PharmaceuticalsChemotherapy
Alliance PharmaceuticalsChemotherapy
Alliance PharmaceuticalsChemotherapy
Alliance PharmaceuticalsChemotherapy
Alliance PharmaceuticalsChemotherapy
Alliance PharmaceuticalsChemotherapy
Alliance PharmaceuticalsChemotherapy
City TherapeuticsAdagrasib
Alliance PharmaceuticalsChemotherapy
Alliance PharmaceuticalsChemotherapy
Alliance PharmaceuticalsChemotherapy
Alliance PharmaceuticalsChemotherapy
Alliance PharmaceuticalsChemotherapy
Alliance PharmaceuticalsChemotherapy
Alliance PharmaceuticalsChemotherapy

Showing 15 of 20 trials with date data

Clinical Trials (21)

Total enrollment: 4,192 patients across 21 trials

Probiotic Therapy in Preventing Gastrointestinal Complications in Patients Undergoing Chemotherapy and Pelvic Radiation Therapy

0
Phase 3Withdrawn

CD2 Lozenges in Preventing Acute Oral Mucositis in Patients With Head and Neck Cancer Receiving Radiotherapy and Chemotherapy

Start: Apr 20120
Phase 3Withdrawn

Doxepin Hydrochloride in Treating Oral Mucositis Pain in Patients With Head and Neck Cancer Undergoing Radiation Therapy With or Without Chemotherapy

Start: Dec 2010Est. completion: Mar 2015155 patients
Phase 3Completed

Radiation Therapy With Concomitant and Adjuvant Temozolomide Versus Radiation Therapy With Adjuvant PCV Chemotherapy in Patients With Anaplastic Glioma or Low Grade Glioma

Start: Sep 2009Est. completion: Oct 2029305 patients
Phase 3Active Not Recruiting

Baclofen-Amitriptyline Hydrochloride-Ketamine Gel in Treating Peripheral Neuropathy Caused by Chemotherapy in Patients With Cancer

Start: Feb 2008Est. completion: Jan 2010208 patients
Phase 3Completed

Vitamin E in Preventing Peripheral Neuropathy Caused by Chemotherapy in Patients Receiving Chemotherapy for Cancer

Start: Dec 2006Est. completion: Aug 2014207 patients
Phase 3Completed

A Randomized Phase III Study of Vitamins B6 and B12 to Prevent Chemotherapy-Induced Neuropathy in Cancer Patients

Start: Jul 2006Est. completion: Jun 2015319 patients
Phase 3Completed

PROSPECT: Chemotherapy Alone or Chemotherapy Plus Radiation Therapy in Treating Patients With Locally Advanced Rectal Cancer Undergoing Surgery

Start: Jun 2012Est. completion: Jun 20241,194 patients
Phase 2/3Unknown

Immunotherapy Biomarkers to Predict First-line PD(L)1-based Immunotherapy Response and Selection of Second-line Treatment in Stage IIIB-IV Non-small Cell Lung Cancer, IMMUNO-BIOMAP Trial

Start: Sep 2026Est. completion: Sep 2028
Phase 2Not Yet Recruiting

A Study of Targeted Post-Surgery Radiation Therapy for Non-Small Cell Lung Cancer With Remaining Lymph Node Cancer After Treatment

Start: Mar 2026Est. completion: Mar 2032164 patients
Phase 2Not Yet Recruiting

CHIO3 Trial: CHemotherapy Combined With Immune Checkpoint Inhibitor for Operable Stage IIIA/B Non-Small Cell Lung Cancer

Start: Mar 2021Est. completion: Jul 202638 patients
Phase 2Active Not Recruiting

Combination Chemotherapy With or Without Hypofractionated Radiation Therapy Before Surgery in Treating Patients With Pancreatic Cancer

Start: Dec 2016126 patients
Phase 2Unknown

Surgery to Remove the Sentinel Lymph Node and Axillary Lymph Nodes After Chemotherapy in Treating Women With Stage II, Stage IIIA, or Stage IIIB Breast Cancer

Start: Jul 2009Est. completion: Apr 2023756 patients
Phase 2Completed

Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage I or Stage II Hodgkin's Lymphoma

Start: May 2004Est. completion: May 2011104 patients
Phase 2Completed

Combination Chemotherapy in Treating Patients With Relapsed or Refractory Intermediate-Grade or High-Grade Non-Hodgkin's Lymphoma

Start: Jul 2000
Phase 2Completed

Chemotherapy Followed by Radiation Therapy in Treating Adults With Supratentorial Glioma

Start: Jul 1996Est. completion: Jul 200443 patients
Phase 2Completed
NCT05501665Varian Medical SystemsBiospecimen Collection

Split Course Adaptive Radiation Therapy With Pembrolizumab With/Without Chemotherapy for Treating Stage IV Lung Cancer

Start: May 2023Est. completion: Feb 2027
Phase 1/2Recruiting

Combination Chemotherapy in Treating Patients With Relapsed or Refractory Hodgkin's Lymphoma

Start: Jul 2000Est. completion: Feb 200791 patients
Phase 1/2Completed
NCT03546361Merck & Co.Autologous Dendritic Cell-Adenovirus CCL21 Vaccine

CCL21-Gene Modified Dendritic Cell Vaccine and Pembrolizumab in Treating Patients With Stage IV Non-small Cell Lung Cancer

Start: Jul 2019Est. completion: Jan 202724 patients
Phase 1Active Not Recruiting

Decision Aid for the Improvement of Decision-Making in Patients With Non-small Cell Lung Cancer

Start: Aug 2020Est. completion: Dec 202698 patients
N/AActive Not Recruiting

Diagnostic Procedures in Women With Locally Advanced Breast Cancer Who Are Receiving Chemotherapy Before Breast Cancer Surgery

Start: Feb 2002Est. completion: May 2012360 patients
N/ACompleted

Related Jobs in Oncology

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

1 actively recruiting trials targeting 4,192 patients
6 companies competing in this space