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Fallopian Tube Cancer

Oncology
10
Pipeline Programs
12
Companies
13
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
4
0
4
0
2
0
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Monoclonal Antibody
267%
Small Molecule
133%
+ 13 programs with unclassified modality

Oncology is a $53.9B market in consolidation, dominated by a handful of megacap players with blockbuster franchises approaching patent expiration.

$53.9B marketConsolidating→ Stable30 products15 companies

Key Trends

  • Heavy patent cliff exposure (REVLIMID $3.9B LOE 2028, JAKAFI $1.9B LOE 2028)
  • Kinase inhibitors and immunomodulatory agents dominate spend; limited diversification in top 10
  • Clinical trial volume remains exceptionally high (29,145 trials) but concentration in Phase 1-2 signals early-stage pipeline challenges

Career Verdict

Strong near-term opportunity for R&D and medical affairs roles, but competitive landscape and patent cliff urgency favor specialists over generalists.

AI-generated market analysis based on FDA, CMS, ClinicalTrials.gov, and hiring data

Market Leaders

#1ELIQUISStable
$18.3B
Bristol Myers Squibb·Launch15.0yr
#2FARXIGAStable
$4.3B
AstraZeneca·Peak15.4yr
#3REVLIMIDDeclining
$3.9B
Bristol Myers Squibb·LOE Approaching1.8yr
#4XTANDIStable
$2.6B
Astellas·Peak10.7yr
#5IMBRUVICAStable
$2.4B
AbbVie·Peak8.9yr

Drug Class Breakdown

FXa Inhibitors
$18.3B(34%)

concentrated in single product

SGLT2 Inhibitors
$4.3B(8%)

single dominant product

Kinase Inhibitors
$4.0B(7%)

multi-product class, competitive

Immunomodulatory Agents (Cereblon)
$3.9B(7%)

facing near-term patent cliff

Androgen Receptor Antagonists
$2.6B(5%)

prostate cancer specialty

Protein Kinase Inhibitors
$2.4B(4%)

niche hematologic oncology

JAK Inhibitors
$1.9B(4%)

near-term LOE exposure

Career Outlook

Stable

Oncology remains a premium therapeutic area but faces structural headwinds: top 10 products account for >80% of spend, patent cliffs loom (REVLIMID 2028), and late-stage pipeline thinness suggests slower near-term growth. However, high trial volume and consolidation create demand for specialized expertise in regulatory, clinical operations, and lifecycle management. Pharma professionals with kinase inhibitor, immunomodulatory, or ADC experience are in highest demand.

Breaking In

Entry-level candidates should target CROs (Thermo Fisher, IQVIA), emerging biotech (BeiGene, BeOne), or contract manufacturing; oncology specialization requires demonstrated domain knowledge.

For Experienced Professionals

Experienced professionals should focus on lifecycle/patent strategy roles (high salary, low headcount) or pivot to emerging modalities (ADCs, bispecifics) to avoid commoditization in crowded kinase inhibitor space.

In-Demand Skills

Regulatory strategy & PDUFA navigationKinase inhibitor development (small molecule)Clinical trial operations & site managementLifecycle management & patent strategyMedical affairs (oncology-specific science)Manufacturing scale-up (small molecule & biotech)

Best For

Regulatory Affairs ManagerClinical Operations ManagerMedical Science Liaison (MSL) — OncologyLifecycle ManagerR&D Scientist (medicinal chemistry, ADME)Manufacturing Engineer

Hiring Landscape

$102K–$266K

Oncology hiring is actively concentrated at Thermo Fisher Scientific (CRO/CDMO services, 559 jobs), AstraZeneca (208 jobs), and emerging biotech players like BeiGene (185 jobs). Commercial roles dominate (412 jobs, $136K avg) but R&D positions offer the highest salary premium ($199K avg, 347 roles). Patent cliff urgency is creating acute demand for regulatory, CMC, and lifecycle management expertise.

1,946
Open Roles
5
Companies Hiring
5
Departments

Top Hiring Companies

208Stable
185Growing
167Growing
147Growing

By Department

Commercial(21%)
$136K
Research & Development(18%)
$199K
Clinical Operations(5%)
$181K
Medical Affairs(4%)
$266K
Manufacturing(5%)
$102K

Strong near-term hiring momentum, especially in CRO/CDMO and emerging biotech; Medical Affairs offers highest compensation but limited headcount.

Competitive Landscape

12 companies ranked by most advanced pipeline stage

Nordic Pharma
Nordic PharmaFrance - Paris
2 programs
2
TCGPhase 31 trial
carboplatinPhase 31 trial
Active Trials
NCT00052468Completed1,742Est. Jan 2011
NCT00004934CompletedEst. May 2003
Sharp Therapeutics
Sharp TherapeuticsPA - Pittsburgh
2 programs
1
1
PembrolizumabPhase 2Monoclonal Antibody1 trial
recombinant adenovirus-p53 SCH-58500Phase 11 trial
Active Trials
NCT00002960Completed59Est. Jul 2000
NCT02834975Terminated26Est. Dec 2022
MSD
MSDIreland - Ballydine
2 programs
1
1
PembrolizumabPhase 2Monoclonal Antibody
recombinant adenovirus-p53 SCH-58500Phase 1
AstraZeneca
AstraZenecaCAMBRIDGE, United Kingdom
1 program
1
plevitrexedPhase 21 trial
Active Trials
NCT00014690CompletedEst. Feb 2004
Bayer
BayerLEVERKUSEN, Germany
1 program
1
sorafenib tosylatePhase 21 trial
Active Trials
NCT00522301Terminated6Est. Mar 2008
Syndax Pharmaceuticals
1 program
1
EntinostatPhase 1Small Molecule1 trial
Active Trials
NCT03924245Terminated3Est. Feb 2022
Alliance Pharmaceuticals
1 program
1
KetorolacPhase 11 trial
Active Trials
NCT01670799Completed29Est. Dec 2015
Genentech
GenentechCA - Oceanside
2 programs
D4064APHASE_11 trial
AvastinPHASE_21 trial
Active Trials
NCT00753480Suspended56
NCT00504257Completed45Est. Oct 2012
Boston Scientific
Boston ScientificCA - Valencia
1 program
Hysteroscopic cell sampling of the fallopian tubeN/A1 trial
Active Trials
NCT03593681Completed150Est. Feb 2020
City Therapeutics
City TherapeuticsMA - Cambridge
1 program
filgrastimPHASE_11 trial
Active Trials
NCT00550784CompletedEst. Oct 2014
Merck & Co.
Merck & Co.RAHWAY, NJ
1 program
recombinant adenovirus-p53 SCH-58500PHASE_1
Sanofi
SanofiPARIS, France
1 program
ILX-295501PHASE_21 trial
Active Trials
NCT00005645Withdrawn0

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Nordic PharmaTCG
Nordic Pharmacarboplatin
Sharp TherapeuticsPembrolizumab
Bayersorafenib tosylate
GenentechAvastin
AstraZenecaplevitrexed
SanofiILX-295501
Syndax PharmaceuticalsEntinostat
Alliance PharmaceuticalsKetorolac
GenentechD4064A
City Therapeuticsfilgrastim
Sharp Therapeuticsrecombinant adenovirus-p53 SCH-58500
Boston ScientificHysteroscopic cell sampling of the fallopian tube

Clinical Trials (13)

Total enrollment: 2,116 patients across 13 trials

Carboplatin/Paclitaxel +/-Gemcitabine in Treating Patients With Ovarian Epithelial or Fallopian Tube Cancer

Start: Aug 2002Est. completion: Jan 20111,742 patients
Phase 3Completed

Paclitaxel and Carboplatin With or Without Epirubicin in Treating Patients With Stage IIB, Stage III, or Stage IV Invasive Ovarian Epithelial, Fallopian Tube, or Peritoneal Cancer

Start: Aug 1999Est. completion: May 2003
Phase 3Completed

Pembrolizumab, Paclitaxel, and Carboplatin in Patients With Advanced Stage Epithelial Ovarian Cancer (EOC).

Start: Dec 2016Est. completion: Dec 202226 patients
Phase 2Terminated
NCT00522301Bayersorafenib tosylate

Sorafenib in Treating Patients With Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Peritoneal Cancer in at Least the Second Remission

Start: Jul 2007Est. completion: Mar 20086 patients
Phase 2Terminated

Avastin in Combination With Docetaxel in Ovarian/Fallopian Tube/Peritoneum Carcinoma

Start: Mar 2007Est. completion: Oct 201245 patients
Phase 2Completed

ZD9331 With or Without Topotecan in Treating Patients With Refractory or Recurrent Epithelial Ovarian Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer

Start: Mar 2001Est. completion: Feb 2004
Phase 2Completed

ILX-295501 in Treating Patients With Stage III or Stage IV Ovarian Cancer That Has Not Responded to Previous Treatment

Start: May 19990
Phase 2Withdrawn

Olaparib and Entinostat in Patients With Recurrent, Platinum-Refractory, Resistant Ovarian, Primary Peritoneal, Fallopian Tube Cancers

Start: Oct 2020Est. completion: Feb 20223 patients
Phase 1Terminated

Availability & Effect of Post-OP Ketorolac on Ovarian, Fallopian Tube or Primary Peritoneal Cancer

Start: Mar 2012Est. completion: Dec 201529 patients
Phase 1Completed

A Study of D4064A Administered to Patients With Recurrent or Persistent Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

Start: Sep 200856 patients
Phase 1Suspended

Combination Chemotherapy and Autologous Peripheral Stem Cell Transplant in Treating Patients With Stage III, Stage IV, or Recurrent Ovarian Epithelial Cancer, Primary Peritoneal Cancer, or Fallopian Tube Cancer

Start: Jan 2001Est. completion: Oct 2014
Phase 1Completed
NCT00002960Sharp Therapeuticsrecombinant adenovirus-p53 SCH-58500

SCH-58500 in Treating Patients With Primary Ovarian, Fallopian Tube, or Peritoneal Cancer (C95084)

Start: Jun 1999Est. completion: Jul 200059 patients
Phase 1Completed
NCT03593681Boston ScientificHysteroscopic cell sampling of the fallopian tube

Compare Fallopian Tube Cells Collected by Cytuity With Removed Ovarian/Tubal Tissue to Determine Presence of Malignancy

Start: Aug 2018Est. completion: Feb 2020150 patients
N/ACompleted

Related Jobs in Oncology

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

2 late-stage (Phase 3) programs, potential near-term approvals
12 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.