Mereo BioPharma(MREO)
UK - London
PharmaceuticalFocus: Acquisition & rapid development of drugs
Mereo BioPharma is a life sciences company focused on Acquisition & rapid development of drugs.
OncologyEndocrinologyWomen's HealthRespiratoryNephrology
Funding Stage
PUBLIC
Open Jobs
0
Pipeline & Clinical Trials
Vantictumab
Pancreatic CancerClinical Trials (1)
NCT02005315A Study of Vantictumab (OMP-18R5) in Combination With Nab-Paclitaxel and Gemcitabine in Previously Untreated Stage IV Pancreatic Cancer
Phase 1Demcizumab
Primary Peritoneal CarcinomaClinical Trials (1)
NCT01952249A Study of Demcizumab Plus Paclitaxel in Subjects With Platinum Resistant Ovarian
Phase 1OMP-305B83
Advanced Solid Tumor MalignanciesClinical Trials (1)
NCT02298387A Phase 1 Study of OMP-305B83 in Subjects With Solid Tumors
Phase 1Phase 1
Clinical Trials (1)
NCT02722954A Phase 1b Study of Demcizumab Plus Pembrolizumab in Locally Advanced or Metastatic Solid Tumors
Phase 1OMP-305B83
Cancer OvariesClinical Trials (1)
NCT03030287A Phase 1b Study of OMP-305B83 Plus Paclitaxel in Subjects With Ovarian, Peritoneal or Fallopian Tube Cancer
Phase 1Docetaxel
Solid TumorsClinical Trials (1)
NCT01957007A Study of Vantictumab (OMP-18R5) in Combination With Docetaxel in Patients With Previously Treated NSCLC
Phase 1OMP-54F28, Paclitaxel and Carboplatin
Ovarian CancerClinical Trials (1)
NCT02092363Dose Escalation Study of OMP-54F28 in Combination With Paclitaxel and Carboplatin in Patients With Recurrent Platinum-Sensitive Ovarian Cancer
Phase 1OMP-131R10
Advanced Relapsed TumorsClinical Trials (1)
NCT02482441A Phase 1a/b Dose Escalation Study of the Safety, Pharmacokinetics, and Pharmacodynamics of OMP-131R10
Phase 1OMP-59R5
Solid TumorsClinical Trials (1)
NCT01277146A Dose Escalation Study of OMP-59R5 in Subjects With Solid Tumors
Phase 1Demcizumab
Pancreatic CancerClinical Trials (1)
NCT01189929A Study of Gemcitabine and Demcizumab (OMP-21M18) With or Without Abraxane® as 1st-line Treatment in Subjects With Locally Advanced or Metastatic Pancreatic Cancer
Phase 1OMP-336B11
Locally Advanced Malignant NeoplasmClinical Trials (1)
NCT03295942A Study of OMP-336B11 in Subjects With Locally Advanced or Metastatic Tumors
Phase 1OMP-21M18
Colorectal CancerClinical Trials (1)
NCT01189942A Study of FOLFIRI Plus OMP-21M18 as 1st or 2nd-line Treatment in Subjects With Metastatic Colorectal Cancer
Phase 1OMP-305B83
Metastatic Colorectal CancerClinical Trials (1)
NCT03035253A Study of OMP-305B83 in Subjects With Metastatic Colorectal Cancer
Phase 1OMP-21M18
Solid TumorsClinical Trials (1)
NCT00744562A Phase 1 Dose Escalation Study of OMP-21M18 in Subjects With Solid Tumors
Phase 1brontictuzumab
Metastatic Colorectal CancerClinical Trials (1)
NCT03031691A Study of Brontictuzumab With Chemotherapy for Subjects With Previously Treated Metastatic Colorectal Cancer
Phase 1Phase 1
Clinical Trials (1)
NCT01703572A Dose Escalation Study of OMP-52M51 in Subjects With Lymphoid Malignancies
Phase 1Demcizumab
Non Small Cell Lung CancerClinical Trials (1)
NCT01189968A Study of Carboplatin and Pemetrexed Plus Demcizumab (OMP-21M18) in Subjects With Non-Squamous Non-Small Cell Lung Cancer
Phase 1OMP-18R5
Solid TumorsClinical Trials (1)
NCT01345201A Dose Escalation Study of OMP-18R5 in Subjects With Solid Tumors
Phase 1OMP-313M32
Locally Advanced CancerClinical Trials (1)
NCT03119428A Study of OMP-313M32 in Subjects With Locally Advanced or Metastatic Solid Tumors
Phase 1OMP-54F28
Solid TumorsOMP-52M51
Relapsed or Refractory Solid TumorsClinical Trials (1)
NCT01778439A Dose Escalation Study of OMP-52M51 in Subjects With Solid Tumors
Phase 1Vantictumab combined with paclitaxel
Metastatic Breast CancerClinical Trials (1)
NCT01973309A Study of Vantictumab (OMP-18R5) in Combination With Paclitaxel in Locally Recurrent or Metastatic Breast Cancer
Phase 1BCT197
InteractionClinical Trials (1)
NCT03498170The Effect of Itraconazole on BCT197 Exposure in Healthy Male Participants
Phase 1OMP-54F28 with Sorafenib
Hepatocellular CancerClinical Trials (1)
NCT02069145Dose Escalation Study of OMP-54F28 in Combination With Sorafenib in Patients With Hepatocellular Cancer
Phase 1OMP-54F28, Nab-Paclitaxel and Gemcitabine
Pancreatic CancerClinical Trials (1)
NCT02050178Dose Escalation Study of OMP-54F28 in Combination With Nab-Paclitaxel and Gemcitabine in Patients With Previously Untreated Stage IV Pancreatic Cancer
Phase 1BCT197
InteractionClinical Trials (1)
NCT02926326The Effect of Azithromycin on BCT197 Exposure in Healthy Male Volunteers
Phase 1MPH966
Hematologic MalignancyClinical Trials (1)
NCT03986086MPH966 for Prevention of Graft-versus-host Disease After Allogeneic Hematopoietic Stem Cell Transplantation
Phase 1/2OMP-59R5
Stage IV Pancreatic CancerClinical Trials (1)
NCT01647828A Phase 1b/2 Study of OMP-59R5 (Tarextumab) in Combination With Nab-Paclitaxel and Gemcitabine in Subjects With Previously Untreated Stage IV Pancreatic Cancer
Phase 1/2Etigilimab
Solid Tumor, AdultClinical Trials (1)
NCT04761198A Study of Etigilimab and Nivolumab in Participants With Locally Advanced or Metastatic Tumors
Phase 1/2Alvelestat
Covid19Clinical Trials (1)
NCT04539795COVID-19 Study of Safety and Tolerability of Alvelestat
Phase 1/2OMP-59R5
Stage IV Small Cell Lung CancerClinical Trials (1)
NCT01859741A Phase 1b/2 Study of OMP-59R5 (Tarextumab) in Combination With Etoposide and Platinum Therapy
Phase 1/2setrusumab
Osteogenesis Imperfecta, Type IClinical Trials (1)
NCT03118570A Study in Adult Patients With Type I, III or IV Osteogenesis Imperfecta Treated With BPS804
Phase 2Phase 2
Clinical Trials (1)
NCT02908074A 6 Month Safety Extension Study of MBGS205
Phase 2BPS804
HypophosphatasiaPhase 2
BPS804 20mg/Kg
OsteopeniaPhase 2
Clinical Trials (1)
NCT02259582A Study of Carboplatin, Pemetrexed Plus Placebo vs Carboplatin, Pemetrexed Plus 1 or 2 Truncated Courses of Demcizumab in Subjects With Non-Squamous Non-Small Cell Lung Cancer
Phase 2Phase 2
Clinical Trials (1)
NCT02730169Safety and Efficacy of BGS649 in Male Obese Subjects With Hypogonadotropic Hypogonadism
Phase 2Placebo Oral Tablet
Alpha 1-Antitrypsin DeficiencyClinical Trials (1)
NCT03636347A 12-week Study Treating Participants Who Have alpha1-antitrypsin-related COPD With Alvelestat (MPH966) or Placebo.
Phase 2Setrusumab
Osteogenesis ImperfectaClinical Trials (1)
NCT05312697Long-term Extension Study of Setrusumab in Adults With Type I, III, or IV Osteogenesis Imperfecta
Phase 2Nivolumab
Ovarian CancerClinical Trials (1)
NCT05715216EON: A Single-arm Phase II Study of Etigilimab (OMP-313M32) in Combination With Checkpoint Inhibition (Nivolumab) in Patients With Platinum-resistant, Recurrent Epithelial Ovarian Cancer
Phase 2Active treatment with a high dose of BGS649
EndometriosisInvestigational new drug company code: BGS649
Obese Hypogonadotropic HypogonadismAlvelestat
Alpha-1 Antitrypsin Deficiency (AATD)Clinical Trials (1)
NCT03679598Alvelestat (MPH966) for the Treatment of ALpha-1 ANTitrypsin Deficiency
Phase 2Demcizumab
Pancreatic CancerClinical Trials (1)
NCT02289898Study of Gemcitabine, Abraxane® Plus Placebo Versus Gemcitabine, Abraxane® Plus 1 or 2 Truncated Courses of Demcizumab in Subjects With 1st-Line Metastatic Pancreatic Ductal Adenocarcinoma
Phase 2BCT197 Part A
Acute Kidney InjuryPhase 2
Clinical Trials (1)
NCT02700919Efficacy and Safety of BCT197 in Subjects With Acute Respiratory Exacerbations of Chronic Obstructive Pulmonary Disease
Phase 2BPS804
Osteogenesis ImperfectaClinical Trials (1)
NCT03216486An Exploratory Study of BPS804 Treatment in Adult Patients With Type I, III or IV Osteogenesis Imperfecta
Phase 2Phase 2
Open Jobs (0)
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Interview Prep Quick Facts
Founded: 2015
Portfolio: 41 clinical trials
SEC Filings: 2 available