Osteopenia
5
Pipeline Programs
8
Companies
6
Clinical Trials
0
Approved Products
Pipeline by Development Stage
Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
0
2
0
2
0
Early DiscoveryClinical DevelopmentMarket
Competitive Landscape
7 companies ranked by most advanced pipeline stage
M&
Merck & Co.RAHWAY, NJ
1 programStudy of Bone Disease in Older HIV-infected AdultsN/A1 trial
Active Trials
Trial Timeline
Clinical trial activity over time
2021
2022
2023
2024
2025
2026
TevaSeasonale
TevaSeasonale
BayerMenostar
AmgenAMG 167
Merck & Co.Study of Bone Disease in Older HIV-infected Adults
Genentechbisphosphonate therapy
Clinical Trials (6)
Total enrollment: 712 patients across 6 trials
Study to Evaluate the Safety and Efficacy of Seasonale for Treatment of Low Bone Mineral Density
Start: Jul 2005Est. completion: Aug 20070
Phase 3Withdrawn
A Study to Evaluate Suppression of the Pituitary-Ovarian Axis With Three Different Oral Contraceptive Regimens
Start: Jun 2005Est. completion: Jun 200636 patients
Phase 3Completed
3-year Study of Menostar Versus Evista to Prevent Osteoporosis in Post-menopausal Women
Start: Feb 2004Est. completion: Jun 2007500 patients
Phase 3Completed
A First-in-human Study Evaluating AMG 167 in Healthy Men and Postmenopausal Women
Start: May 2009Est. completion: Nov 200969 patients
Phase 1Completed
Study of Bone Disease in Older HIV-infected Adults
Start: Dec 2009Est. completion: Feb 2011101 patients
N/ACompleted
Study of Adults With Low Growth Hormone Who Survived Childhood Cancer Where Treatment Caused Low Bone Density
Start: Jun 2002Est. completion: Oct 20086 patients
N/ATerminated
Phase Legend
Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available
Key Insights
2 late-stage (Phase 3) programs — potential near-term approvals
8 companies competing in this space