Solid Tumor, Adult

Oncology
44
Pipeline Programs
30
Companies
40
Clinical Trials
16 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
25
16
3
0
0
0
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Small Molecule
360%
Monoclonal Antibody
240%
+ 41 programs with unclassified modality

Competitive Landscape

32 companies ranked by most advanced pipeline stage

EpicentRx
EpicentRxCA - La Jolla
1 program
1
AdAPT-001Phase 21 trial
Active Trials
NCT04673942RecruitingEst. Mar 2027
Eikon Therapeutics
Eikon TherapeuticsCA - Millbrae
1 program
1
Association atezolizumab + BDB001 + RTPhase 21 trial
Active Trials
NCT03915678Recruiting247Est. Dec 2027
CytoDyn
CytoDynVANCOUVER, WA
1 program
1
LeronlimabPhase 2Monoclonal Antibody1 trial
Active Trials
NCT04504942Completed16Est. Jan 2025
CytomX Therapeutics
CytomX TherapeuticsSOUTH SAN FRANCISCO, CA
5 programs
3
2
CX-2009Phase 1/21 trial
CX-2029Phase 1/21 trial
CX-188Phase 11 trial
CX-2051Phase 11 trial
CX-801Phase 1
Active Trials
NCT03706274WithdrawnEst. Dec 2022
NCT06265688RecruitingEst. Mar 2029
NCT03149549TerminatedEst. Sep 2020
+1 more trials
Tempus
TempusIL - Chicago
3 programs
2
A2B530Phase 1/21 trial
A2B694Phase 1/21 trial
ApheresisN/A1 trial
Active Trials
NCT04981119RecruitingEst. Apr 2029
NCT05736731Active Not RecruitingEst. Dec 2026
NCT06051695RecruitingEst. Jun 2029
M&
Merck & Co.RAHWAY, NJ
3 programs
2
1
GAd-209-FSP low dosePhase 1/21 trial
89Zr-TLX250Phase 11 trial
EOS100850Phase 11 trial
Active Trials
NCT05868174RecruitingEst. Dec 2026
NCT03873883Completed119Est. May 2024
NCT04041310Active Not Recruiting115Est. Oct 2026
DT
3 programs
1
2
DF1001Phase 1/21 trial
DF9001Phase 1/2
DF6215Phase 1
Active Trials
NCT04143711RecruitingEst. Dec 2026
Taiho Oncology
Taiho OncologyNJ - Princeton
1 program
1
ASTX029Phase 1/21 trial
Active Trials
NCT03520075CompletedEst. Mar 2025
Accession Therapeutics
1 program
1
ATTR-01Phase 1/21 trial
Active Trials
NCT06977737Recruiting72Est. Dec 2034
BioInvent International
1 program
1
BI1206Phase 1/21 trial
Active Trials
NCT04219254Recruiting197Est. Nov 2027
Corbus Pharmaceuticals
1 program
1
CRB-701Phase 1/21 trial
Active Trials
NCT06265727Recruiting348Est. Jan 2027
Egle Therapeutics
Egle TherapeuticsFrance - Paris
1 program
1
EGL-001Phase 1/21 trial
Active Trials
NCT06622486RecruitingEst. Jan 2027
Mereo BioPharma
Mereo BioPharmaUK - London
1 program
1
EtigilimabPhase 1/2Monoclonal Antibody1 trial
Active Trials
NCT04761198CompletedEst. Oct 2023
H
HutchmedChina - Hong Kong
1 program
1
HMPL-453Phase 1/21 trial
Active Trials
NCT03160833Unknown33Est. Jun 2020
Regeneron
RegeneronTARRYTOWN, NY
1 program
1
SNS-101Phase 1/21 trial
Active Trials
NCT05864144Active Not Recruiting98Est. Jun 2027
Vivace Therapeutics
Vivace TherapeuticsCA - San Mateo
1 program
1
VT3989Phase 1/21 trial
Active Trials
NCT04665206Recruiting336Est. Jun 2027
Aurigene
AurigeneIndia - Bangalore
2 programs
2
AUR103Phase 11 trial
AUR105Phase 11 trial
Active Trials
NCT05607199Recruiting80Est. Oct 2026
NCT05605119Recruiting40Est. May 2026
BridgeBio Pharma
BridgeBio PharmaCA - Palo Alto
2 programs
2
BBO-10203Phase 11 trial
BBP-398Phase 11 trial
Active Trials
NCT06625775Recruiting392Est. Nov 2028
NCT05480865Terminated28Est. Aug 2024
BeOne Medicines
BeOne MedicinesCA - San Carlos
2 programs
2
BGB-24714Phase 11 trial
LifirafenibPhase 1Small Molecule
Active Trials
NCT05381909TerminatedEst. Jul 2025
Fate Therapeutics
Fate TherapeuticsSAN DIEGO, CA
2 programs
2
FT516Phase 11 trial
FT538Phase 11 trial
Active Trials
NCT04551885TerminatedEst. Aug 2023
NCT05069935TerminatedEst. Aug 2023
IB
Instil BioDALLAS, TX
1 program
1
AXN-2510Phase 11 trial
Active Trials
NCT07159828Active Not RecruitingEst. May 2027
BridgeBio Oncology Therapeutics
BridgeBio Oncology TherapeuticsSOUTH SAN FRANCISCO, CA
1 program
1
BBO-10203Phase 1
Boehringer Ingelheim
Boehringer IngelheimINGELHEIM, Germany
1 program
1
BI 765063Phase 11 trial
Active Trials
NCT03990233Completed100Est. Apr 2025
Bio-Path Holdings
Bio-Path HoldingsBELLAIRE, TX
1 program
1
BP1001-APhase 11 trial
Active Trials
NCT04196257RecruitingEst. Oct 2027
Novo Nordisk
Novo NordiskBAGSVAERD DENMARK, Denmark
1 program
1
DCR-STAT3Phase 11 trial
Active Trials
NCT06098651Completed26Est. Sep 2025
Kazia Therapeutics
Kazia TherapeuticsAustralia - Sydney
1 program
1
EVT801Phase 11 trial
Active Trials
NCT05114668CompletedEst. Nov 2024
GenVivo
GenVivoCA - San Marino
1 program
1
GEN2 + ValganciclovirPhase 1Small Molecule1 trial
Active Trials
NCT06391918Active Not RecruitingEst. Mar 2028
Pierre Fabre
Pierre FabreFrance - Aignan
1 program
1
KIN-2787Phase 11 trial
Active Trials
NCT04913285Active Not Recruiting400Est. Mar 2029
SpringWorks Therapeutics
1 program
1
LifirafenibPhase 1Small Molecule1 trial
Active Trials
NCT03905148CompletedEst. Oct 2025
BT
1
SM08502Phase 11 trial
Active Trials
NCT03355066TerminatedEst. Nov 2022

+2 more companies

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
2030
2031
Eikon TherapeuticsAssociation atezolizumab + BDB001 + RT
EpicentRxAdAPT-001
CytoDynLeronlimab
Accession TherapeuticsATTR-01
Egle TherapeuticsEGL-001
TempusA2B694
Corbus PharmaceuticalsCRB-701
RegeneronSNS-101
TempusA2B530
Vivace TherapeuticsVT3989
Mereo BioPharmaEtigilimab
BioInvent InternationalBI1206
Dragonfly TherapeuticsDF1001
Merck & Co.GAd-209-FSP low dose
CytomX TherapeuticsCX-2029

Showing 15 of 40 trials with date data

Clinical Trials (40)

Total enrollment: 2,747 patients across 40 trials

NCT03915678Eikon TherapeuticsAssociation atezolizumab + BDB001 + RT

Atezolizumab Combined With BDB001 AnD Immunogenic Radiotherapy in Patients With Advanced Solid Tumors

Start: Mar 2021Est. completion: Dec 2027247 patients
Phase 2Recruiting

A Study of AdAPT-001 in Subjects With Sarcoma and Refractory Solid Tumors

Start: Mar 2021Est. completion: Mar 2027
Phase 2Recruiting

Basket Study of Leronlimab (PRO 140) in Patients With CCR5+ Locally Advanced or Metastatic Solid Tumors

Start: May 2020Est. completion: Jan 202516 patients
Phase 2Completed

A Study of ATTR-01 in Participants With Select Epithelial Solid Tumours

Start: Mar 2025Est. completion: Dec 203472 patients
Phase 1/2Recruiting

First-in-human Trial of EGL-001 in Patients with Selected Advanced And/or Metastatic Solid Tumors

Start: Sep 2024Est. completion: Jan 2027
Phase 1/2Recruiting

A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

Start: Apr 2024Est. completion: Jun 2029
Phase 1/2Recruiting

A Phase 1/2 Study to Investigate CRB-701 in Solid Tumors

Start: Apr 2024Est. completion: Jan 2027348 patients
Phase 1/2Recruiting

A Study of SNS-101 (Anti VISTA) Monotherapy and in Combination With Cemiplimab in Patients With Advanced Solid Tumors

Start: May 2023Est. completion: Jun 202798 patients
Phase 1/2Active Not Recruiting

A Study to Evaluate the Safety and Efficacy of A2B530, a Logic-gated CAR T, in Participants With Solid Tumors That Express CEA and Have Lost HLA-A*02 Expression

Start: Apr 2023Est. completion: Dec 2026
Phase 1/2Active Not Recruiting

Study to Evaluate VT3989 in Patients With Metastatic Solid Tumors

Start: Mar 2021Est. completion: Jun 2027336 patients
Phase 1/2Recruiting

A Study of Etigilimab and Nivolumab in Participants With Locally Advanced or Metastatic Tumors

Start: Mar 2021Est. completion: Oct 2023
Phase 1/2Completed

A Study of BI-1206 in Combination With Pembrolizumab in Subjects With Advanced Solid Tumors

Start: Jun 2020Est. completion: Nov 2027197 patients
Phase 1/2Recruiting

Study of DF1001 in Patients with Advanced Solid Tumors

Start: Nov 2019Est. completion: Dec 2026
Phase 1/2Recruiting
NCT04041310Merck & Co.GAd-209-FSP low dose

Nous-209 Genetic Vaccine for the Treatment of Microsatellite Unstable Solid Tumors

Start: Oct 2019Est. completion: Oct 2026115 patients
Phase 1/2Active Not Recruiting

PROCLAIM-CX-2029: A Trial to Find Safe and Active Doses of an Investigational Drug CX-2029 for Patients With Solid Tumors or DLBCL

Start: Jun 2018Est. completion: Jun 2023
Phase 1/2Completed

Study of ASTX029 in Subjects With Advanced Solid Tumors

Start: May 2018Est. completion: Mar 2025
Phase 1/2Completed

PROCLAIM-CX-2009: A Trial to Find Safe and Active Doses of an Investigational Drug CX-2009 for Patients With Selected Solid Tumors

Start: Jun 2017Est. completion: Sep 2020
Phase 1/2Terminated

A Study of HMPL-453 in Patients With Advanced Solid Malignancies

Start: May 2017Est. completion: Jun 202033 patients
Phase 1/2Unknown

A Study to Assess AXN-2510 Treatment in Adult Patients With Advanced Solid Tumors

Start: Sep 2025Est. completion: May 2027
Phase 1Active Not Recruiting

Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

Start: Oct 2024Est. completion: Nov 2028392 patients
Phase 1Recruiting

First In Human Study of CX-2051 in Advanced Solid Tumors

Start: Apr 2024Est. completion: Mar 2029
Phase 1Recruiting
NCT06391918GenVivoGEN2 + Valganciclovir

Phase 1 Study of GEN2 in Patients With Advanced Solid Tumors

Start: Mar 2024Est. completion: Mar 2028
Phase 1Active Not Recruiting

A Study of DCR-STAT3 in Adults With Solid Tumors

Start: Aug 2023Est. completion: Sep 202526 patients
Phase 1Completed

Combination of 177Lu-TLX250 and Peposertib in Patients With Carbonic Anhydrase IX -Expressing Solid Tumors

Start: May 2023Est. completion: Dec 2026
Phase 1Recruiting

First in Human, Dose Escalation, Dose Expansion Study of AUR105

Start: Nov 2022Est. completion: May 202640 patients
Phase 1Recruiting

A First in Human Study of AUR 103 Calcium to Evaluate Safety, Pharmacokinetics and Pharmacodynamics

Start: Sep 2022Est. completion: Oct 202680 patients
Phase 1Recruiting

BP1001-A in Patients With Advanced or Recurrent Solid Tumors

Start: Aug 2022Est. completion: Oct 2027
Phase 1Recruiting

SHP2 Inhibitor BBP-398 in Combination With Sotorasib in Patients With Advanced Solid Tumors and a KRAS-G12C Mutation

Start: Jul 2022Est. completion: Aug 202428 patients
Phase 1Terminated

A Study of BGB-24714 as Monotherapy and With Combination Therapies in Participants With Solid Tumors

Start: Jul 2022Est. completion: Jul 2025
Phase 1Terminated

Safety, Tolerability, and Pharmacokinetics of EVT801 in Patients With Advanced Solid Tumours

Start: Nov 2021Est. completion: Nov 2024
Phase 1Completed

FT538 in Combination With Monoclonal Antibodies in Advanced Solid Tumors

Start: Oct 2021Est. completion: Aug 2023
Phase 1Terminated

A Study to Evaluate KIN-2787 in Participants With BRAF and/or NRAS Mutation Positive Solid Tumors

Start: Aug 2021Est. completion: Mar 2029400 patients
Phase 1Active Not Recruiting

FT516 in Combination With Monoclonal Antibodies in Advanced Solid Tumors

Start: Sep 2020Est. completion: Aug 2023
Phase 1Terminated

PROCLAIM-CX-188: A Trial to Find Safe and Active Doses of an Investigational Drug CX-188 for Patients With Solid Tumors

Start: Jan 2020Est. completion: Dec 2022
Phase 1Withdrawn

Study of the Safety and Pharmacokinetics of BGB-283 (Lifirafenib) and PD-0325901 (Mirdametinib) in Participants With Advanced or Refractory Solid Tumors

Start: May 2019Est. completion: Oct 2025
Phase 1Completed

A Trial of BI 765063 Monotherapy and in Combination With BI 754091 in Patients With Advanced Solid Tumours

Start: Apr 2019Est. completion: Apr 2025100 patients
Phase 1Completed

First-in-Human Study of EOS100850 (Inupadenant) in Patients with Cancer

Start: Feb 2019Est. completion: May 2024119 patients
Phase 1Completed

A Study Evaluating the Safety and Pharmacokinetics of Orally Administered SM08502 in Subjects With Advanced Solid Tumors

Start: Nov 2017Est. completion: Nov 2022
Phase 1Terminated

Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

Start: Oct 2021Est. completion: Apr 2029
N/ARecruiting
NCT04671654Heidelberg PharmaSystematic Evaluation of Human Explant Model Systems Engineering

Systematic Evaluation of Human Explant Model Systems Engineering

Start: Aug 2020Est. completion: Aug 2025100 patients
N/AUnknown

Related Jobs in Oncology

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

16 actively recruiting trials targeting 2,747 patients
30 companies competing in this space