Triple Negative Breast Neoplasms

Oncology
3
Pipeline Programs
3
Companies
3
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
1
2
0
0
0
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Monoclonal Antibody
1100%
+ 2 programs with unclassified modality

Competitive Landscape

3 companies ranked by most advanced pipeline stage

M&
Merck & Co.RAHWAY, NJ
1 program
1
Bintrafusp alfaPhase 21 trial
Active Trials
NCT04489940TerminatedEst. Jul 2022
Pfizer
PfizerNEW YORK, NY
1 program
1
PF-03084014Phase 21 trial
Active Trials
NCT02299635Terminated19Est. Jan 2016
CytoDyn
CytoDynVANCOUVER, WA
1 program
1
350 mg leronlimabPhase 1/2Monoclonal Antibody1 trial
Active Trials
NCT03838367Terminated10Est. Sep 2022

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Merck & Co.Bintrafusp alfa
PfizerPF-03084014
CytoDyn350 mg leronlimab

Clinical Trials (3)

Total enrollment: 29 patients across 3 trials

NCT04489940Merck & Co.Bintrafusp alfa

Bintrafusp Alfa in High Mobility Group AT-Hook 2 (HMGA2) Expressing Triple Negative Breast Cancer

Start: Oct 2020Est. completion: Jul 2022
Phase 2Terminated
NCT02299635PfizerPF-03084014

A Study Evaluating PF-03084014 In Patients With Advanced Breast Cancer With Or Without Notch Alterations

Start: Feb 2015Est. completion: Jan 201619 patients
Phase 2Terminated
NCT03838367CytoDyn350 mg leronlimab

Leronlimab (PRO 140) Combined With Carboplatin in Patients With Cytokine Chemokine Receptor 5 Positive (CCR5+) mTNBC

Start: Apr 2019Est. completion: Sep 202210 patients
Phase 1/2Terminated

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Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

3 companies competing in this space

Related Indications

Breast Cancer(530)Non-small Cell Lung Cancer(373)Prostate Cancer(371)Multiple Myeloma(244)Advanced Solid Tumors(221)Acute Myeloid Leukemia(204)Cancer(187)Neoplasms(173)Colorectal Cancer(166)Advanced Solid Tumor(165)