Squamous Cell Carcinoma of the Head and Neck (SCCHN)

Oncology
3
Pipeline Programs
3
Companies
2
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
2
1
0
0
0
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Monoclonal Antibody
267%
Small Molecule
133%

Competitive Landscape

3 companies ranked by most advanced pipeline stage

Secura Bio
Secura BioNV - Las Vegas
1 program
1
DuvelisibPhase 2Small Molecule1 trial
Active Trials
NCT05057247CompletedEst. Jun 2024
Celldex Therapeutics
1 program
1
Combination of varlilumab and nivolumabPhase 1/2Monoclonal Antibody1 trial
Active Trials
NCT02335918Completed175Est. Dec 2018
Nektar Therapeutics
Nektar TherapeuticsSAN FRANCISCO, CA
1 program
1
avelumabPhase 1/2Monoclonal Antibody

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Secura BioDuvelisib
Celldex TherapeuticsCombination of varlilumab and nivolumab

Clinical Trials (2)

Total enrollment: 175 patients across 2 trials

Duvelisib Plus Docetaxel In Recurrent/Metastatic HNSCC

Start: Oct 2021Est. completion: Jun 2024
Phase 2Completed
NCT02335918Celldex TherapeuticsCombination of varlilumab and nivolumab

A Dose Escalation and Cohort Expansion Study of Anti-CD27 (Varlilumab) and Anti-PD-1 (Nivolumab) in Advanced Refractory Solid Tumors

Start: Jan 2015Est. completion: Dec 2018175 patients
Phase 1/2Completed

Related Jobs in Oncology

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

Monoclonal Antibody is the dominant modality (67% of programs)
3 companies competing in this space