Renal Failure

Nephrology
8
Pipeline Programs
2
Companies
9
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
2
0
5
1
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Small Molecule
1100%
+ 8 programs with unclassified modality

Competitive Landscape

2 companies ranked by most advanced pipeline stage

M&
Merck & Co.RAHWAY, NJ
1 program
1
elbasvirPhase 4Small Molecule1 trial
Active Trials
NCT02945150Completed8Est. Mar 2020
Veloxis Pharmaceuticals
8 programs
2
5
LCP-TacroPhase 31 trial
LCP-TacroPhase 31 trial
PrografPhase 31 trial
PrografPhase 31 trial
Prograf vs Envarsus XR vs Astagraf XLPhase 31 trial
+3 more programs
Active Trials
NCT02411604Approved For Marketing
NCT00496483CompletedEst. Mar 2008
NCT01666951CompletedEst. May 2013
+5 more trials

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Merck & Co.elbasvir
Veloxis PharmaceuticalsPrograf vs Envarsus XR vs Astagraf XL
Veloxis PharmaceuticalsLCP-Tacro
Veloxis PharmaceuticalsPrograf
Veloxis PharmaceuticalsPrograf
Veloxis PharmaceuticalsLCP-Tacro
Veloxis PharmaceuticalsLCP-Tacro tablets
Veloxis PharmaceuticalsLCP Tacro

Clinical Trials (9)

Total enrollment: 8 patients across 9 trials

NCT02945150Merck & Co.elbasvir

Preemptive Treatment With Grazoprevir and Elbasvir for Donor HCV Positive to Recipient HCV Negative Kidney Transplant

Start: Feb 2017Est. completion: Mar 20208 patients
Phase 4Completed
NCT02339246Veloxis PharmaceuticalsPrograf vs Envarsus XR vs Astagraf XL

Pharmacokinetic Comparison Of All FK-506 Formulations

Start: Jan 2015Est. completion: Mar 2015
Phase 3Completed
NCT01962922Veloxis PharmaceuticalsLCP-Tacro

Crossover Study to Compare PK of Once Daily LCP-Tacro Tablets to Generic Tacrolimus Capsules Twice Daily.

Start: Nov 2013Est. completion: Aug 2015
Phase 3Completed
NCT01438710Veloxis PharmaceuticalsPrograf

Switching Study of Kidney Transplant Patients With Tremor to LCP-Tacro (STRATO)

Start: Dec 2011Est. completion: Jul 2015
Phase 3Completed
NCT01187953Veloxis PharmaceuticalsPrograf

Double-Blind,Double-Dummy,Efficacy/Safety,LCP-Tacro™ Vs Prograf®,Prevention Rejection,De Novo Adult Kidney Tx

Start: Sep 2010Est. completion: Mar 2014
Phase 3Completed
NCT00817206Veloxis PharmaceuticalsLCP-Tacro

Safety and Efficacy of LCP-Tacro™ Once Daily in Stable Renal Transplant Patients Converted From Prograf® Twice Daily

Start: Dec 2008Est. completion: Feb 2011
Phase 3Completed
NCT01666951Veloxis PharmaceuticalsLCP-Tacro tablets

Multicenter, Prospective, Rand, PK Study of LCP-Tacro™ Compared to Prograf® Capsules in De Novo Adult Kidney Transplant

Start: Nov 2012Est. completion: May 2013
Phase 2Completed
NCT00496483Veloxis PharmaceuticalsLCP Tacro

Pharmacokinetics of LCP-Tacro in Stable Kidney Transplant Patients

Start: Jul 2007Est. completion: Mar 2008
Phase 2Completed
NCT02411604Veloxis PharmaceuticalsTacrolimus

Expanded Access Study for Renal Transplant Patients With Envarsus XR ™

N/AApproved For Marketing

Related Jobs in Nephrology

Thesis work, 60 credits – Establishing In Vitro Models of Mitochondrial Dysfunction in Acute Kidney Injury for Preclinical Drug Discovery

AstraZeneca
Sweden - Gothenburg
6d ago

Director, Strategy & Operations-Nephrology Franchise

Biogen
Cambridge, MA
1w ago
$195K - $269K/yr

Associate Director – Nephrology Market Access Strategy

Biogen
Cambridge, MA
1w ago
$164K - $226K/yr

Vice President, Head of Renal Sales

Novartis
Field Non-Sales (USA)
1w ago
$274K - $510K/yr

Medical Science Liaison, CardioRenal - Portland, OR

AstraZeneca
Portland - OR, US
1w ago

Area Sales Manager (Florida Region)

Outset Medical
Florida Region
1w ago

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

5 late-stage (Phase 3) programs — potential near-term approvals
2 companies competing in this space

Related Indications

Chronic Kidney Disease(86)Renal Impairment(67)End Stage Renal Disease(56)Kidney Transplantation(49)Renal Insufficiency(27)Chronic Kidney Diseases(25)Kidney Transplant(19)Diabetic Nephropathies(18)Kidney Diseases(17)Kidney Transplant Rejection(16)