Kidney Transplant

Nephrology
4
Pipeline Programs
13
Companies
11
Clinical Trials
1 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
0
2
0
0
1
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Monoclonal Antibody
1100%
+ 10 programs with unclassified modality

Competitive Landscape

10 companies ranked by most advanced pipeline stage

Novartis
NovartisBASEL, Switzerland
1 program
1
Enteric-Coated Mycophenolate SodiumPhase 41 trial
Active Trials
NCT00537862Completed200
Allergy Therapeutics
Allergy TherapeuticsUK - West Sussex
2 programs
1
1
InfliximabPhase 2Monoclonal Antibody1 trial
CyclophosphamidePhase 11 trial
Active Trials
NCT06056102RecruitingEst. Dec 2042
NCT02495077CompletedEst. Jul 2021
Tonix Pharmaceuticals
Tonix PharmaceuticalsBERKELEY HEIGHTS, NJ
1 program
1
TNX-1500Phase 21 trial
Active Trials
NCT07204080Not Yet RecruitingEst. Jun 2029
Roche
RocheSTAVANGER NORWAY, Norway
1 program
CellCeptN/A1 trial
Active Trials
NCT00281619Completed29Est. Feb 2010
Abbott
AbbottABBOTT PARK, IL
1 program
Continuous Glucose Monitoring for Post-kidney Transplantation in Pre-existing Type 2 DiabetesN/A1 trial
Active Trials
NCT07271433Completed20Est. Jan 2026
Pfizer
PfizerNEW YORK, NY
1 program
Long-term Follow-up of Spare the Nephron (STN) PatientsN/A1 trial
Active Trials
NCT01126333Completed128Est. Jun 2015
AstraZeneca
AstraZenecaCAMBRIDGE, United Kingdom
1 program
Nova Max Pro StatSensor deviceN/A1 trial
Active Trials
NCT07392710Completed100Est. Dec 2024
Heidelberg Pharma
Heidelberg PharmaGermany - Ladenburg
1 program
Predictive Accuracy of Machine Perfusion for Kidney Transplant Outcomes in GermanyN/A1 trial
Active Trials
NCT07348874Not Yet Recruiting300Est. Feb 2028
Providence Therapeutics
1 program
Prospective Donor Specific Antibody (DSA) Monitoring ProtocolN/A1 trial
Active Trials
NCT01382355UnknownEst. Aug 2012
Astellas
AstellasChina - Shenyang
1 program
SNP: CYP3A5 gene polymorphismsN/A1 trial
Active Trials
NCT02377791Unknown170Est. Oct 2015

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
2030
2031
NovartisEnteric-Coated Mycophenolate Sodium
Tonix PharmaceuticalsTNX-1500
Allergy TherapeuticsInfliximab
Allergy TherapeuticsCyclophosphamide
Heidelberg PharmaPredictive Accuracy of Machine Perfusion for Kidney Transplant Outcomes in Germany
AbbottContinuous Glucose Monitoring for Post-kidney Transplantation in Pre-existing Type 2 Diabetes
AstraZenecaNova Max Pro StatSensor device
AstellasSNP: CYP3A5 gene polymorphisms
Providence TherapeuticsProspective Donor Specific Antibody (DSA) Monitoring Protocol
PfizerLong-term Follow-up of Spare the Nephron (STN) Patients
RocheCellCept

Clinical Trials (11)

Total enrollment: 947 patients across 11 trials

NCT00537862NovartisEnteric-Coated Mycophenolate Sodium

Efficacy and Safety of Enteric-coated Mycophenolate Sodium (EC-MPS) in a Cyclosporine Microemulsion Based Regimen in de Novo Living Donor Kidney Transplant Recipients

Start: May 2006200 patients
Phase 4Completed
NCT07204080Tonix PharmaceuticalsTNX-1500

(TNX-1500) in Kidney Transplant Recipients

Start: Jul 2026Est. completion: Jun 2029
Phase 2Not Yet Recruiting
NCT02495077Allergy TherapeuticsInfliximab

Effects of Inhibiting Early Inflammation in Kidney Transplant Patients

Start: Nov 2015Est. completion: Jul 2021
Phase 2Completed
NCT06056102Allergy TherapeuticsCyclophosphamide

CAR-T Cell Therapy for Desensitization in Kidney Transplantation

Start: May 2024Est. completion: Dec 2042
Phase 1Recruiting
NCT07348874Heidelberg PharmaPredictive Accuracy of Machine Perfusion for Kidney Transplant Outcomes in Germany

Predictive Accuracy of Machine Perfusion for Kidney Transplant Outcomes in Germany

Start: Jan 2026Est. completion: Feb 2028300 patients
N/ANot Yet Recruiting
NCT07271433AbbottContinuous Glucose Monitoring for Post-kidney Transplantation in Pre-existing Type 2 Diabetes

Continuous Glucose Monitoring for Post-kidney Transplantation in Pre-existing Type 2 Diabetes

Start: Jan 2024Est. completion: Jan 202620 patients
N/ACompleted
NCT07392710AstraZenecaNova Max Pro StatSensor device

Clinical Evaluation of the Nova Max Pro StatSensor Device

Start: Feb 2023Est. completion: Dec 2024100 patients
N/ACompleted
NCT02377791AstellasSNP: CYP3A5 gene polymorphisms

Impact of CYP3A5 Gene Polymorphisms on Tacrolimus Concentrations and Outcomes in Thai Transplant Recipients

Start: Jul 2014Est. completion: Oct 2015170 patients
N/AUnknown
NCT01382355Providence TherapeuticsProspective Donor Specific Antibody (DSA) Monitoring Protocol

Prospective Donor Specific Antibody (DSA) Monitoring Protocol

Start: Aug 2011Est. completion: Aug 2012
N/AUnknown
NCT01126333PfizerLong-term Follow-up of Spare the Nephron (STN) Patients

Long-term Follow-up of Spare the Nephron (STN) Patients

Start: Jun 2010Est. completion: Jun 2015128 patients
N/ACompleted
NCT00281619RocheCellCept

PK-PD Study of Mycophenolic Acid (CellCept) in Pediatric Kidney Transplant Patients

Start: Jan 2006Est. completion: Feb 201029 patients
N/ACompleted

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Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

1 actively recruiting trials targeting 947 patients
13 companies competing in this space

Related Indications

Chronic Kidney Disease(86)Renal Impairment(67)End Stage Renal Disease(56)Kidney Transplantation(49)Renal Insufficiency(27)Chronic Kidney Diseases(25)Diabetic Nephropathies(18)Kidney Diseases(17)Kidney Transplant Rejection(16)Acute Kidney Injury(16)