Recurrent Diffuse Large B-Cell Lymphoma

Oncology
6
Pipeline Programs
6
Companies
5
Clinical Trials
2 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
4
1
1
0
0
0
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Small Molecule
267%
Monoclonal Antibody
133%
+ 3 programs with unclassified modality

Competitive Landscape

6 companies ranked by most advanced pipeline stage

Regeneron
RegeneronTARRYTOWN, NY
1 program
1
OdronextamabPhase 2Monoclonal Antibody1 trial
Active Trials
NCT06784726Recruiting27Est. Apr 2033
AbbVie
AbbVieNORTH CHICAGO, IL
1 program
1
Biospecimen CollectionPhase 1/21 trial
Active Trials
NCT06536049Recruiting38Est. Dec 2028
ADC Therapeutics
ADC TherapeuticsNJ - New Providence
1 program
1
Autologous Hematopoietic Stem Cell TransplantationPhase 11 trial
Active Trials
NCT05228249WithdrawnEst. Oct 2027
Nektar Therapeutics
Nektar TherapeuticsSAN FRANCISCO, CA
1 program
1
CyclophosphamidePhase 11 trial
Active Trials
NCT05359211Active Not RecruitingEst. Sep 2026
Secura Bio
Secura BioNV - Las Vegas
1 program
1
DuvelisibPhase 1Small Molecule
Novartis
NovartisBASEL, Switzerland
1 program
1
DuvelisibPhase 1Small Molecule1 trial
Active Trials
NCT04890236Completed4Est. Sep 2024

Trial Timeline

Clinical trial activity over time

2022
2023
2024
2025
2026
2027
2028
2029
2030
2031
RegeneronOdronextamab
AbbVieBiospecimen Collection
ADC TherapeuticsAutologous Hematopoietic Stem Cell Transplantation
Nektar TherapeuticsCyclophosphamide
NovartisDuvelisib

Clinical Trials (5)

Total enrollment: 69 patients across 5 trials

Odronextamab for Relapsed and Refractory Large B-cell Lymphomas Before CAR-T

Start: Sep 2025Est. completion: Apr 203327 patients
Phase 2Recruiting
NCT06536049AbbVieBiospecimen Collection

Epcoritamab Plus Ibrutinib for the Treatment of Relapsed or Refractory Aggressive B-Cell Non-Hodgkin Lymphoma

Start: Apr 2025Est. completion: Dec 202838 patients
Phase 1/2Recruiting
NCT05228249ADC TherapeuticsAutologous Hematopoietic Stem Cell Transplantation

Loncastuximab Tesirine in Combination With Chemotherapy Prior to Stem Cell Transplant for the Treatment of Recurrent or Refractory Diffuse Large B-Cell Lymphoma

Start: Apr 2023Est. completion: Oct 2027
Phase 1Withdrawn

NKTR-255 in Combination With CAR-T Cell Therapy for the Treatment of Relapsed or Refractory Large B-cell Lymphoma

Start: Dec 2022Est. completion: Sep 2026
Phase 1Active Not Recruiting

Duvelisib Exposure to Enhance Immune Profiles of T Cells in Patients With Recurrent or Refractory Diffuse Large B-Cell Lymphoma, DEEP T CELLS Study

Start: Jan 2022Est. completion: Sep 20244 patients
Phase 1Completed

Related Jobs in Oncology

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

2 actively recruiting trials targeting 69 patients
6 companies competing in this space