Recurrent Diffuse Large B-Cell Lymphoma
Oncology
6
Pipeline Programs
6
Companies
5
Clinical Trials
2 recruiting
0
Approved Products
Pipeline by Development Stage
Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
4
1
1
0
0
0
Early DiscoveryClinical DevelopmentMarket
Drug Modality Breakdown
Small Molecule
267%
Monoclonal Antibody
133%
+ 3 programs with unclassified modality
Competitive Landscape
6 companies ranked by most advanced pipeline stage
ADC TherapeuticsNJ - New Providence
1 program1
Autologous Hematopoietic Stem Cell TransplantationPhase 11 trial
Active Trials
Trial Timeline
Clinical trial activity over time
2022
2023
2024
2025
2026
2027
2028
2029
2030
2031
RegeneronOdronextamab
AbbVieBiospecimen Collection
ADC TherapeuticsAutologous Hematopoietic Stem Cell Transplantation
Nektar TherapeuticsCyclophosphamide
NovartisDuvelisib
Clinical Trials (5)
Total enrollment: 69 patients across 5 trials
Odronextamab for Relapsed and Refractory Large B-cell Lymphomas Before CAR-T
Start: Sep 2025Est. completion: Apr 203327 patients
Phase 2Recruiting
Epcoritamab Plus Ibrutinib for the Treatment of Relapsed or Refractory Aggressive B-Cell Non-Hodgkin Lymphoma
Start: Apr 2025Est. completion: Dec 202838 patients
Phase 1/2Recruiting
Loncastuximab Tesirine in Combination With Chemotherapy Prior to Stem Cell Transplant for the Treatment of Recurrent or Refractory Diffuse Large B-Cell Lymphoma
Start: Apr 2023Est. completion: Oct 2027
Phase 1Withdrawn
NKTR-255 in Combination With CAR-T Cell Therapy for the Treatment of Relapsed or Refractory Large B-cell Lymphoma
Start: Dec 2022Est. completion: Sep 2026
Phase 1Active Not Recruiting
Duvelisib Exposure to Enhance Immune Profiles of T Cells in Patients With Recurrent or Refractory Diffuse Large B-Cell Lymphoma, DEEP T CELLS Study
Start: Jan 2022Est. completion: Sep 20244 patients
Phase 1Completed
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Phase Legend
Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available
Key Insights
2 actively recruiting trials targeting 69 patients
6 companies competing in this space