ELIQUIS
PeakNDAORALTABLET, FOR SUSPENSIONPriority Review
Approved
Dec 2012
Lifecycle
Peak
Competitive Pressure
0/100
Clinical Trials
10
Data completeness
7/8 — Comprehensive
Priority Review
ELIQUIS by Bristol Myers Squibb is fxa. Approved for deep vein thrombosis (dvt), which may lead to pulmonary embolism (pe), knee replacement surgery and 7 more indications. First approved in 2012.
Drug data last refreshed 13h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
ELIQUIS (apixaban) is an oral Factor Xa inhibitor approved in 2012 for prevention and treatment of venous thromboembolism, stroke/systemic embolism in atrial fibrillation, and post-surgical thromboprophylaxis. It works by inhibiting both free and clot-bound Factor Xa, reducing thrombin generation and thrombus development without requiring antithrombin III. The drug is a small-molecule direct oral anticoagulant (DOAC) that does not directly affect platelet aggregation.
$18.3BPart D
Peak4.9 years to LOEPeak commercial lifecycle with $18.3B in annual Part D spending indicates a mature, high-capacity franchise supporting large branded teams across commercial, medical affairs, and patient services.
Mechanism of Action
FXa. It does not require antithrombin III for antithrombotic activity. Apixaban inhibits free and clot-bound FXa, and prothrombinase activity. Apixaban has no direct effect on platelet aggregation, but indirectly inhibits platelet aggregation induced by thrombin. By inhibiting FXa, apixaban…
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.