Primary Membranous Nephropathy
Nephrology
6
Pipeline Programs
5
Companies
4
Clinical Trials
3 recruiting
1
Approved Products
Pipeline by Development Stage
Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
1
3
1
1
Early DiscoveryClinical DevelopmentMarket
Drug Modality Breakdown
Small Molecule
150%
Monoclonal Antibody
150%
+ 3 programs with unclassified modality
On Market (1)
Approved therapies currently available
Competitive Landscape
5 companies ranked by most advanced pipeline stage
Trial Timeline
Clinical trial activity over time
2023
2024
2025
2026
2027
2028
2029
BiogenFelzartamab
Zai LabPovetacicept
BeOne MedicinesZanubrutinib
Climb Biobudoprutug
Clinical Trials (4)
Total enrollment: 534 patients across 4 trials
A Study to Learn More About the Effects and Safety of Felzartamab Infusions in Adults With Primary Membranous Nephropathy (PMN)
Start: May 2025Est. completion: Mar 2029180 patients
Phase 3Recruiting
A Study to Evaluate Efficacy, Safety, and Tolerability of Povetacicept in Participants With Primary Membranous Nephropathy (pMN)
Start: Sep 2025Est. completion: Dec 2028176 patients
Phase 2/3Recruiting
A Study to Examine the Efficacy and Safety of Zanubrutinib Given to Adults With Primary Membranous Nephropathy
Start: Apr 2023Est. completion: Oct 2027178 patients
Phase 2/3Active Not Recruiting
A Phase 2 Study of Budoprutug in Subjects With Primary Membranous Nephropathy
Start: Aug 2025Est. completion: Oct 2027
Phase 2Recruiting
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Phase Legend
Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available
Key Insights
1 late-stage (Phase 3) programs — potential near-term approvals
3 actively recruiting trials targeting 534 patients
5 companies competing in this space