Non-Small-Cell Lung Carcinoma NSCLC

Oncology
1
Pipeline Programs
1
Companies
13
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
1
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

1 companies ranked by most advanced pipeline stage

AstraZeneca
AstraZenecaCAMBRIDGE, United Kingdom
1 program
1
MEDI4736Phase 35 trials
Active Trials
NCT02558894Completed65Est. Jun 2017
NCT02527434Completed64Est. Mar 2023
NCT02588131Unknown40Est. Mar 2018
+2 more trials

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
AstraZenecaMEDI4736
AstraZenecaMEDI4736
AstraZenecaMEDI4736
AstraZenecaMEDI4736
AstraZenecaMEDI4736
AstraZenecaMEDI4736
AstraZenecaMEDI4736
AstraZenecaMEDI4736
AstraZenecaMEDI4736
AstraZenecaMEDI4736
AstraZenecaMEDI4736
AstraZenecaMEDI4736
AstraZenecaMEDI4736

Clinical Trials (13)

Total enrollment: 3,834 patients across 13 trials

Study of MEDI4736 Monotherapy and in Combination With Tremelimumab Versus Standard of Care Therapy in Patients With Head and Neck Cancer

Start: Sep 2015Est. completion: Nov 2020736 patients
Phase 3Completed

Phase III Open Label First Line Therapy Study of MEDI 4736 (Durvalumab) With or Without Tremelimumab Versus SOC in Non Small-Cell Lung Cancer (NSCLC)

Start: Jul 2015Est. completion: Dec 20261,118 patients
Phase 3Active Not Recruiting

Study of AZD9291 Plus MEDI4736 Versus AZD9291 Monotherapy in NSCLC After Previous EGFR TKI Therapy in T790M Mutation Positive Tumours

Start: Jul 2015Est. completion: Jun 202329 patients
Phase 3Completed

A Global Study to Assess the Effects of MEDI4736 Following Concurrent Chemoradiation in Patients With Stage III Unresectable Non-Small Cell Lung Cancer

Start: May 2014Est. completion: Aug 2023713 patients
Phase 3Completed

Phase II Study of MEDI4736 Monotherapy or in Combinations With Tremelimumab in Metastatic Pancreatic Ductal Carcinoma

Start: Nov 2015Est. completion: Jun 201765 patients
Phase 2Completed

Study of Tremelimumab in Patients With Advanced Solid Tumors

Start: Nov 2015Est. completion: Mar 202364 patients
Phase 2Completed

A Study of Tremelimumab Combined With the Anti-PD-L1 MEDI4736 Antibody in Malignant Mesothelioma (NIBIT-MESO-1)

Start: Oct 2015Est. completion: Mar 201840 patients
Phase 2Unknown

Phase II Study of MEDI4736, Tremelimumab, and MEDI4736 in Combination w/ Tremelimumab Squamous Cell Carcinoma of the Head and Neck

Start: Apr 2015Est. completion: Jul 2020267 patients
Phase 2Completed

Evaluate the Efficacy of MEDI4736 in Immunological Subsets of Advanced Colorectal Cancer

Start: Dec 2014Est. completion: Jun 202016 patients
Phase 2Completed

Phase II Study of MEDI4736 Monotherapy in Treatment of Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck

Start: Oct 2014Est. completion: Jul 2020112 patients
Phase 2Completed

Study to Assess MEDI4736 With Either AZD9150 or AZD5069 in Advanced Solid Tumors & Relapsed Metastatic Squamous Cell Carcinoma of Head & Neck

Start: Aug 2015Est. completion: Oct 2025340 patients
Phase 1/2Completed

Ph1 to Assess Safety, Tolerability of Tremelimumab/ Tremelimumab+MEDI4736 in Japanese Solid Malignancies/ Mesothelioma

Start: May 2014Est. completion: Jan 201765 patients
Phase 1Completed

A Phase I, Open-Label, Multicentre Study to Evaluate the Safety, Tolerability and Pharmacokinetics of MEDI4736 in Patients With Advanced Solid Tumours

Start: Sep 2013Est. completion: Nov 2020269 patients
Phase 1Completed

Related Jobs in Oncology

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

1 late-stage (Phase 3) programs — potential near-term approvals
1 companies competing in this space