Neoplasm Metastasis

Oncology
10
Pipeline Programs
8
Companies
9
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
7
0
3
0
0
0
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Small Molecule
150%
Monoclonal Antibody
150%
+ 9 programs with unclassified modality

Competitive Landscape

8 companies ranked by most advanced pipeline stage

Boehringer Ingelheim
Boehringer IngelheimINGELHEIM, Germany
2 programs
1
1
EzabenlimabPhase 2Monoclonal Antibody1 trial
zongertinibPhase 1Small Molecule1 trial
Active Trials
NCT04886804Active Not Recruiting608Est. Aug 2028
NCT03697304Completed211Est. Dec 2024
Genentech
GenentechCA - Oceanside
1 program
1
DocetaxelPhase 2
Pfizer
PfizerNEW YORK, NY
1 program
1
Tanezumab 10 mg IVPhase 21 trial
Active Trials
NCT00545129Completed59Est. Feb 2012
AstraZeneca
AstraZenecaCAMBRIDGE, United Kingdom
3 programs
3
AZD2281Phase 11 trial
AZD2281Phase 11 trial
DS-8201aPhase 1
Active Trials
NCT00633269Completed6Est. Oct 2008
NCT00710268Completed18Est. Nov 2009
GC Biopharma
GC BiopharmaKorea - Yongin
1 program
1
GC1118Phase 11 trial
Active Trials
NCT02352571UnknownEst. Jun 2017
Eli Lilly and Company
Eli Lilly and CompanyINDIANAPOLIS, IN
1 program
1
LY2940680Phase 11 trial
Active Trials
NCT01919398Completed19Est. Jun 2017
Novartis
NovartisBASEL, Switzerland
1 program
1
Paclitaxel plus PTK787Phase 11 trial
Active Trials
NCT00731861Completed28Est. Aug 2010
Alliance Pharmaceuticals
1 program
Intensity Modulated RadiotherapyN/A1 trial
Active Trials
NCT02753790Completed29Est. Apr 2022

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
Boehringer IngelheimEzabenlimab
PfizerTanezumab 10 mg IV
Boehringer Ingelheimzongertinib
GC BiopharmaGC1118
Eli Lilly and CompanyLY2940680
AstraZenecaAZD2281
AstraZenecaAZD2281
NovartisPaclitaxel plus PTK787
Alliance PharmaceuticalsIntensity Modulated Radiotherapy

Clinical Trials (9)

Total enrollment: 978 patients across 9 trials

NCT03697304Boehringer IngelheimEzabenlimab

Platform Trial Evaluating Safety and Efficacy of Ezabenlimab Anti- PD-1 Based Combination Therapies in PD-(L)1 naïve and PD- (L)1 Pretreated Patient Populations With Advanced/Metastatic Solid Tumours

Start: Mar 2019Est. completion: Dec 2024211 patients
Phase 2Completed
NCT00545129PfizerTanezumab 10 mg IV

A Study Of Tanezumab as Add-On Therapy to Opioid Medication In Patients With Pain Due To Cancer That Has Spread To Bone

Start: Apr 2009Est. completion: Feb 201259 patients
Phase 2Completed
NCT04886804Boehringer Ingelheimzongertinib

Beamion LUNG-1: A Study to Test Different Doses of Zongertinib in People With Different Types of Advanced Cancer (Solid Tumours With Changes in the HER2 Gene)

Start: Jul 2021Est. completion: Aug 2028608 patients
Phase 1Active Not Recruiting
NCT02352571GC BiopharmaGC1118

Safety Study of GC1118 (Recombinant Human Anti-EGFR Antibody) in Patients With Advanced Solid Cancer

Start: Jan 2015Est. completion: Jun 2017
Phase 1Unknown
NCT01919398Eli Lilly and CompanyLY2940680

A Study of LY2940680 in Japanese Participants With Advanced Cancers

Start: Aug 2013Est. completion: Jun 201719 patients
Phase 1Completed
NCT00710268AstraZenecaAZD2281

Study to Assess Safety & Tolerability of AZD2281 in Combination With Bevacizumab in Patients With Advanced Solid Tumours

Start: Jun 2008Est. completion: Nov 200918 patients
Phase 1Completed
NCT00633269AstraZenecaAZD2281

Study Assessing Metabolism, Excretion and Pharmacokinetics of a Poly (ADP-Ribose) Polymerase (PARP) Inhibitor in Patients With Solid Metastatic Tumours

Start: Apr 2008Est. completion: Oct 20086 patients
Phase 1Completed
NCT00731861NovartisPaclitaxel plus PTK787

Phase I, Pharmacokinetic, Pharmacodynamic Trial of PTK787 and Paclitaxel in Combination for Advanced Solid Tumors

Start: May 2005Est. completion: Aug 201028 patients
Phase 1Completed
NCT02753790Alliance PharmaceuticalsIntensity Modulated Radiotherapy

Whole Brain Radiation Using IMRT for Patients With Brain Metastases

Start: Mar 2016Est. completion: Apr 202229 patients
N/ACompleted

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Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

8 companies competing in this space

Related Indications

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