Myelogenous Leukemia, Acute

Oncology
4
Pipeline Programs
3
Companies
5
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
3
0
1
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

3 companies ranked by most advanced pipeline stage

Race Oncology
Race OncologyAustralia - Sydney
1 program
1
BisantrenePhase 21 trial
Active Trials
NCT04989335UnknownEst. Dec 2025
Roche
RocheSTAVANGER NORWAY, Norway
2 programs
2
RO5045377Phase 11 trial
RO5429083Phase 12 trials
Active Trials
NCT01635296Completed43Est. Oct 2013
NCT01641250Completed44Est. Feb 2015
NCT01358903Completed65Est. Mar 2014
M&
Merck & Co.RAHWAY, NJ
1 program
1
MK-8776Phase 11 trial
Active Trials
NCT00907517Terminated24Est. Jun 2011

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Race OncologyBisantrene
RocheRO5429083
RocheRO5045377
RocheRO5429083
Merck & Co.MK-8776

Clinical Trials (5)

Total enrollment: 176 patients across 5 trials

NCT04989335Race OncologyBisantrene

Bisantrene Combination for Resistant AML

Start: Aug 2021Est. completion: Dec 2025
Phase 2Unknown
NCT01641250RocheRO5429083

A Study of RO5429083 Alone or in Combination With Cytarabine in Patients With Acute Myelogenous Leukemia

Start: Aug 2012Est. completion: Feb 201544 patients
Phase 1Completed
NCT01635296RocheRO5045377

A Study of RO5045337 in Combination With Cytarabine in Patients With Acute Myelogenous Leukemia

Start: Jul 2012Est. completion: Oct 201343 patients
Phase 1Completed
NCT01358903RocheRO5429083

A Study of RO5429083 in Patients With Metastatic and/or Locally Advanced, CD44-Expressing, Malignant Solid Tumors

Start: Jun 2011Est. completion: Mar 201465 patients
Phase 1Completed
NCT00907517Merck & Co.MK-8776

Study of SCH 900776 (MK-8776) With and Without Cytarabine in Participants With Acute Leukemias (P05247)

Start: Jul 2009Est. completion: Jun 201124 patients
Phase 1Terminated

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Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

3 companies competing in this space

Related Indications

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