XPOVIO

Peak

selinexor

NDAORALTABLETPriority Review
Approved
Jul 2019
Lifecycle
Peak
Competitive Pressure
0/100
Clinical Trials
20

Mechanism of Action

Nuclear Export Inhibitors

Pharmacologic Class:

Nuclear Export Inhibitor

Clinical Trials (5)

NCT07479979Phase 1/2Not Yet Recruiting

Study of Selinexor With Carfilzomib, Isatuximab and Dexamethasone for Patients With Relapsed and/or Refractory Multiple Myeloma

Started Jul 2026
62 enrolled
Relapse Multiple MyelomaRefractory Multiple Myeloma
NCT07447817Phase 2Not Yet Recruiting

Selinexor and Pacritinib in JAK Inhibitor-naïve MF Patients With Cytopenias

Started May 2026
26 enrolled
MyelofibrosisPost-polycythemia Vera MyelofibrosisPost-essential Thrombocythemia Myelofibrosis
NCT07200102Phase 1Not Yet Recruiting

Selinexor Maintenance Post CAR-T Cell Therapy for Multiple Myeloma

Started Mar 2026
20 enrolled
Multiple Myeloma
NCT07138209Phase 3Recruiting

A Study Comparing QLS32015 Monotherapy Versus Pomalidomide, Dexamethasone (Pd) or Selinexor, Dexamethasone (Sd) in Participants With Relapsed or Refractory Multiple Myeloma

Started Nov 2025
228 enrolled
Relapsed or Refractory Multiple Myeloma
NCT05980806Phase 2Recruiting

A Study of Selinexor Monotherapy in Subjects With JAK Inhibitor-naïve Myelofibrosis and Moderate Thrombocytopenia

Started Apr 2024
58 enrolled
MyelofibrosisModerate ThrombocytopeniaMild Thrombocytopenia

Loss of Exclusivity

LOE Date
Aug 14, 2035
114 months away
Patent Expiry
Aug 14, 2035
Exclusivity Expiry
Dec 18, 2027

Patent Records (5)

Patent #ExpiryTypeUse Code
9714226
Jul 26, 2032
SubstanceProduct
10544108
Jul 26, 2032
U-2584
11034660
Jul 26, 2032
U-3018
11787771
Jul 26, 2032
U-3018
12291508
Jul 26, 2032
U-3018