Metastatic Solid Tumor

Oncology
7
Pipeline Programs
8
Companies
8
Clinical Trials
1 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
3
2
2
0
0
0
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

ADC
2100%
+ 7 programs with unclassified modality

Competitive Landscape

8 companies ranked by most advanced pipeline stage

GS
Gilead SciencesFOSTER CITY, CA
2 programs
2
Sacituzumab Govitecan-hziyPhase 2ADC1 trial
Sacituzumab Govitecan-hziyPhase 2ADC
Active Trials
NCT03964727Active Not Recruiting223Est. Dec 2026
Immunophotonics
ImmunophotonicsMO - St. Louis
1 program
1
1.0% IP-001 for InjectionPhase 1/21 trial
Active Trials
NCT05688280Active Not RecruitingEst. Feb 2025
H
HutchmedChina - Hong Kong
1 program
1
Surufatinib and Tislelizumab _ Part 1Phase 1/21 trial
Active Trials
NCT04579757Terminated87Est. Aug 2024
Coherus Oncology
Coherus OncologyCA - Redwood City
1 program
1
CHS-114Phase 11 trial
Active Trials
NCT06657144Recruiting154Est. May 2027
ImmunityBio
ImmunityBioSAN DIEGO, CA
1 program
1
M-CENK, Suspension for Infusion, CryopreservedPhase 11 trial
Active Trials
NCT04898543Active Not Recruiting50Est. May 2026
Pliant Therapeutics
Pliant TherapeuticsCA - South SF
1 program
1
PLN-101095Phase 11 trial
Active Trials
NCT06270706Unknown77Est. Dec 2025
Bristol Myers Squibb
1 program
Recommendation for treatment with immunotherapyN/A1 trial
Active Trials
NCT04447651Active Not Recruiting6Est. Aug 2026
Amgen
AmgenTHOUSAND OAKS, CA
1 program
nonmyeloablative stem cell transplantN/A1 trial
Active Trials
NCT00997529Completed14Est. Jun 2010

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
Gilead SciencesSacituzumab Govitecan-hziy
Immunophotonics1.0% IP-001 for Injection
HutchmedSurufatinib and Tislelizumab _ Part 1
Coherus OncologyCHS-114
Pliant TherapeuticsPLN-101095
ImmunityBioM-CENK, Suspension for Infusion, Cryopreserved
Bristol Myers SquibbRecommendation for treatment with immunotherapy
Amgennonmyeloablative stem cell transplant

Clinical Trials (8)

Total enrollment: 611 patients across 8 trials

NCT03964727Gilead SciencesSacituzumab Govitecan-hziy

Study of Sacituzumab Govitecan in Participants With Metastatic Solid Tumors

Start: Oct 2019Est. completion: Dec 2026223 patients
Phase 2Active Not Recruiting
NCT05688280Immunophotonics1.0% IP-001 for Injection

Intratumoral Injection of IP-001 Following Thermal Ablation in Patients With CRC, NSCLC, and STS

Start: Nov 2022Est. completion: Feb 2025
Phase 1/2Active Not Recruiting
NCT04579757HutchmedSurufatinib and Tislelizumab _ Part 1

Surufatinib in Combination With Tislelizumab in Subjects With Advanced Solid Tumors

Start: Mar 2021Est. completion: Aug 202487 patients
Phase 1/2Terminated
NCT06657144Coherus OncologyCHS-114

A Study of CHS-114 in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors

Start: Apr 2025Est. completion: May 2027154 patients
Phase 1Recruiting
NCT06270706Pliant TherapeuticsPLN-101095

A Phase 1 Study of PLN-101095 in Adults With Advanced or Metastatic Solid Tumors

Start: Aug 2023Est. completion: Dec 202577 patients
Phase 1Unknown
NCT04898543ImmunityBioM-CENK, Suspension for Infusion, Cryopreserved

QUILT-3.076: Study of Autologous M-CENK in Subjects With Locally Advanced or Metastatic Solid Tumors

Start: Jun 2021Est. completion: May 202650 patients
Phase 1Active Not Recruiting
NCT04447651Bristol Myers SquibbRecommendation for treatment with immunotherapy

Patient Response to Immunotherapy Using Spliceosome Mutational Markers (PRISMM)

Start: Sep 2020Est. completion: Aug 20266 patients
N/AActive Not Recruiting
NCT00997529Amgennonmyeloablative stem cell transplant

Mini Allo Stem Cell Transplantation for the Treatment of Solid Tumors

Start: Nov 2000Est. completion: Jun 201014 patients
N/ACompleted

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Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

1 actively recruiting trials targeting 611 patients
8 companies competing in this space

Related Indications

Breast Cancer(530)Non-small Cell Lung Cancer(373)Prostate Cancer(371)Multiple Myeloma(244)Advanced Solid Tumors(221)Acute Myeloid Leukemia(204)Cancer(187)Neoplasms(173)Colorectal Cancer(166)Advanced Solid Tumor(165)