Marginal Zone Lymphoma
Oncology
6
Pipeline Programs
5
Companies
4
Clinical Trials
1 recruiting
0
Approved Products
Pipeline by Development Stage
Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
5
0
1
0
Early DiscoveryClinical DevelopmentMarket
Drug Modality Breakdown
Small Molecule
267%
Monoclonal Antibody
133%
+ 3 programs with unclassified modality
Competitive Landscape
5 companies ranked by most advanced pipeline stage
CelltrionKorea - Incheon
2 programs2
CopanlisibPhase 2Small Molecule
RituximabPhase 2Monoclonal Antibody
ADC TherapeuticsNJ - New Providence
1 program1
Loncastuximab tesirine 150 µg/KgPhase 21 trial
Active Trials
Trial Timeline
Clinical trial activity over time
2021
2022
2023
2024
2025
2026
2027
2028
2029
PentixaPharm[68Ga]Ga-PentixaFor
ADC TherapeuticsLoncastuximab tesirine 150 µg/Kg
HutchmedHMPL-689
TG TherapeuticsUmbralisib
Clinical Trials (4)
Total enrollment: 199 patients across 4 trials
[68Ga]Ga-PentixaFor-PET Imaging for Staging of Marginal Zone Lymphoma
Start: May 2024Est. completion: Jul 2025
Phase 3Terminated
Open-label of Loncastuximab Tesirine (ADCT-402) in Relapsed/Refractory Marginal Zone Lymphoma
Start: Jun 2022Est. completion: Jun 2029
Phase 2Recruiting
Clinical Study of HMPL-689 for Relapsed/Refractory Marginal Zone Lymphoma and Follicular Lymphoma
Start: Apr 2021Est. completion: Feb 2024178 patients
Phase 2Completed
Study to Assess the Efficacy and Safety of Umbralisib in Participants With Non-Follicular Indolent Non-Hodgkin's Lymphoma
Start: Nov 2017Est. completion: Feb 202221 patients
Phase 2Completed
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Phase Legend
Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available
Key Insights
1 late-stage (Phase 3) programs — potential near-term approvals
1 actively recruiting trials targeting 199 patients
5 companies competing in this space