BRUKINSA

LaunchSM

zanubrutinib

NDAORALCAPSULE
Approved
Jun 2025
Lifecycle
Launch
Competitive Pressure
0/100
Clinical Trials
20

Mechanism of Action

Bruton's Tyrosine Kinase Inhibitors

Pharmacologic Class:

Kinase Inhibitor

Clinical Trials (5)

NCT07341191Phase 2Not Yet Recruiting

Sonrotoclax Plus Zanubrutinib in Patients With Relapsed/Refractory Mantle Cell Lymphoma Planned for Standard of Care CAR-T Cell Therapy

Started Mar 2026
NCT06859008Phase 1Recruiting

Zanubrutinib in Combination With Sonrotoclax for the Treatment of Underrepresented Ethnic and Racial Minorities With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma

Started Feb 2026
NCT07277231Phase 3Recruiting

A Study to Investigate Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Acalabrutinib in Adults With Previously Untreated Chronic Lymphocytic Leukemia

Started Jan 2026
500 enrolled
Chronic Lymphocytic Leukemia
NCT07321652Phase 3Not Yet Recruiting

Testing the Addition of Anti-Cancer Drug Sonrotoclax, to the Standard Treatment Zanubrutinib, for Previously Untreated CLL/SLL

Started Jan 2026
466 enrolled
Chronic Lymphocytic LeukemiaSmall Lymphocytic Leukemia
NCT07169331Phase 4Recruiting

A Study to Evaluate the Efficacy and Safety of Zanubrutinib in Chinese Adults With Treatment-Naive Waldenström Macroglobulinemia

Started Oct 2025

Loss of Exclusivity

LOE Date
Jan 19, 2043
205 months away
Patent Expiry
Jan 19, 2043
Exclusivity Expiry
Mar 7, 2031

Patent Records (5)

Patent #ExpiryTypeUse Code
10570139
Apr 22, 2034
U-2145
11142528
Apr 22, 2034
Product
U-2145
9447106
Apr 22, 2034
SubstanceProduct
U-3860
11970500
Aug 15, 2037
U-2145
11591340
Aug 15, 2037
U-3729