Leukemia, Lymphocytic, Chronic

Oncology
4
Pipeline Programs
4
Companies
4
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
1
3
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

4 companies ranked by most advanced pipeline stage

E
EisaiChina - Liaoning
1 program
1
ONTAKPhase 21 trial
Active Trials
NCT00055146Completed41Est. May 2006
Sanofi
SanofiPARIS, France
1 program
1
alvocidibPhase 21 trial
Active Trials
NCT00464633Completed165Est. Dec 2011
BioCryst Pharmaceuticals
1 program
1
forodesine hydrochloridePhase 21 trial
Active Trials
NCT00289549Completed8Est. Jan 2009
Pfizer
PfizerNEW YORK, NY
1 program
1
SGN-40Phase 1/21 trial
Active Trials
NCT00283101Completed12Est. Oct 2006

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Sanofialvocidib
BioCryst Pharmaceuticalsforodesine hydrochloride
EisaiONTAK
PfizerSGN-40

Clinical Trials (4)

Total enrollment: 226 patients across 4 trials

NCT00464633Sanofialvocidib

Alvocidib in Patients With Previously Treated Chronic Lymphocytic Leukemia or Prolymphocytic Leukemia Arising From Chronic Lymphocytic Leukemia (CLL)

Start: Mar 2007Est. completion: Dec 2011165 patients
Phase 2Completed
NCT00289549BioCryst Pharmaceuticalsforodesine hydrochloride

Study of Forodesine Hydrochloride in Patients With Advanced, Fludarabine-refractory Chronic Lymphocytic Leukemia (CLL)

Start: Jun 2005Est. completion: Jan 20098 patients
Phase 2Completed
NCT00055146EisaiONTAK

Study of ONTAK in Patients With B-Cell Chronic Lymphocytic Leukemia (CLL)

Start: Mar 2003Est. completion: May 200641 patients
Phase 2Completed
NCT00283101PfizerSGN-40

A Safety Study in Patients With Chronic Lymphocytic Leukemia

Start: Jul 2005Est. completion: Oct 200612 patients
Phase 1/2Completed

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Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

4 companies competing in this space

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