Ischemic Heart Failure

Cardiovascular
3
Pipeline Programs
4
Companies
4
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
0
1
0
1
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

4 companies ranked by most advanced pipeline stage

Rhythm Pharmaceuticals
1 program
1
Coronary artery bypass graftingPhase 31 trial
Active Trials
NCT00846001CompletedEst. Sep 2010
Sanofi
SanofiPARIS, France
1 program
1
Cellular TherapyPhase 21 trial
Active Trials
NCT00102128TerminatedEst. Apr 2007
HELP Therapeutics
HELP TherapeuticsChina - Nanjing
1 program
1
HumanPhase 11 trial
Active Trials
NCT05566600UnknownEst. Jul 2025
Zoll
ZollCA - San Jose
1 program
LifeVestN/A1 trial
Active Trials
NCT02700880CompletedEst. Feb 2019

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Rhythm PharmaceuticalsCoronary artery bypass grafting
SanofiCellular Therapy
HELP TherapeuticsHuman
ZollLifeVest

Clinical Trials (4)

NCT00846001Rhythm PharmaceuticalsCoronary artery bypass grafting

Resynchronization Surgery Combined Unified Efficacy

Start: Sep 2007Est. completion: Sep 2010
Phase 3Completed
NCT00102128SanofiCellular Therapy

Study to Examine the Safety and Effectiveness of Implanted Skeletal Muscle Cells (Cells Removed From the Thigh Muscle) Into Scarred Areas of Heart Muscle After Heart Attack.

Start: Nov 2002Est. completion: Apr 2007
Phase 2Terminated
NCT05566600HELP TherapeuticsHuman

Allogeneic iPSC-derived Cardiomyocyte Therapy in Patients With Worsening Ischemic Heart Failure

Start: Oct 2022Est. completion: Jul 2025
Phase 1Unknown
NCT02700880ZollLifeVest

LifeVest Wearable Cardioverter Defibrillator WEARIT-III Registry

Start: Jun 2014Est. completion: Feb 2019
N/ACompleted

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Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

1 late-stage (Phase 3) programs — potential near-term approvals
4 companies competing in this space

Related Indications

Heart Failure(334)Hypertension(333)Coronary Artery Disease(295)Atrial Fibrillation(288)Pulmonary Arterial Hypertension(103)Acute Coronary Syndrome(62)Pulmonary Hypertension(55)Essential Hypertension(32)Coronary Heart Disease(28)Aortic Valve Stenosis(27)